just ordered ab0ottle.
Look up "serotonin" and "fibrosis" on pubmed. Scary info about heart and liver tisue containing HT (serotonin) receptors that seem to cause fibrosis and other problems with the heart and apparently liver too when serotonin activated those receptors.
This worries me some when considering my supplememntation with Tryptophan and has held me back from jumping to . Does anyone have clarifying info about this issue?
just ordered ab0ottle.
Again, not trying to be a ****, start a fight or piss you off, just giving a brief editorial of my opinions on the matter. has worked wonders for me and many many others, and in my research I never came across anything indicating fibrosis.
Tryptophan/5-HTP are not going to raise your seratonin levels to such extreme levels that seratonin-related illnesses are going to arise. If you are at normal serotonin levels, then either trypt or 5htp will then convert to melatonin.
[QUOTE=nevergoodenough;2073703]Not sure about your question, but I always find queries like this slightly humorous. Not meaning to be condesending at all, just pointing out my opinion. The majority of us on this board dump bottles and bottles of artificial chemicals and hormones, that we know nothing about, into our bodies (ie, prohormones, fat burners, etc. etc.) without a second thought. Not because we don't research, but because with 'proprietary blends" its hard to tell exactly what is in something. But when it comes to more naturally occuring products like 5-htp, or fenugreek, and even soy people tend to pour over the minutia and become very concerned with highly unlikely outcomes. I'm not saying don't do your due dilligence when it comes to research before trying products, but sifting through every obscure study may be a little overkill.
Yeah.. I agree.. 5-HTP is a naturally occurring amino acid. A LOT of herbs out there are not naturally occuring in our body and we take it anyway because of the claims and research. But even with the research science can't identify everything that is in it. You hear all the time how science discovered a "new" compound in a plant or herb. Those compounds aren't new.. they were already there. Amino acids are a pretty safe bet. They make up our DNA. You just have to use some precautions. You don't wanna take this along with anxiety/sleep/depression meds. Usually with amino acids we know more what they do then some herb blend.
I just ordered a bottle of primaforce 5-htp. Best quality for price I have found.
Lord, whom shall we go away to? You have sayings of everlasting life"- John 6:68
WHAT has science offered?
Not to guide people down another path, but if you tend to get symptom resolution from 5HTP, and your symptoms are mainly psychological (ie anxiety or depression or "cranky" or whatever), there might be a place for an SSRI or some other RX. Maybe ask your doc.
Then again, not everyone wants "depression" as a diagnosis on their permanent medical record.
I didn't look for "serotonin" and "fibrosis", but I'm assuming they are case studies from patients with carcinoid tumors? If so, these people have an intestinal tumor that produces MASSIVE amounts of serotonin, causing symptoms like flushing, wheezing, diarrhea and edema...and eventually, the acronym "TIPS" describes their "heart fibrosis"...Tricuspid Insufficiency and Pulmonary Stenosis (tricusp valve regurgitation and pulmonary valve stenosis, both right sided heart issues). It only effects the right side of the heart b/c serotonin is converted quickly in the lungs and does not usually reach the left side of the heart in enough of a concentration to cause damage.
8g of fish oil per day worked better than 5HTP at improving my mood