You're going to have to mega-dose it due to it's low bio-availability in the body.
prison pen pals??? i don't know what happened to pa...lol. but when he came out with 6oxo extreme it was the first time i had ever heard of resveratrol. google giant nutrition and look at recommended dosing for their bulk resveratrol-both ergopharm and giant nutrition are affiliated with patrick arnold.
Resveratrol was around here WAY before 6-OXO extreme. PA put in 6-OXO because of an obscure relation to a SERM, that is essentially ineffective as such.
aha-you are much better versed than i, but the release of 6oxo extreme was my first exposure to resveratrol. and pa played a big part in it's popularity, imo. btw-i thought pa was touting it's ability to increase test, wasn't it other companies who touted it's serm like qualities?
Yeah, that is where the Testosterone stimulation theories have come from is PA. Res has serm like properties, but IMHO are severely overblown. PA started it, and others cited him... so as the chain went on, it got blown up out of proportion.
right on, DA. as usual you are on it...i was very skeptical of 6oxo extreme and it's HIGH price tag, but i did break down and try it. got to admit the libido boost after a week was insane. but at 10 caps a day that shiit was too pricey.
I like 6-OXO myself... that is what gives me a nice boost all around... ATD is to harsh and compete for receptors. Just some strait 6-OXO (Generic) is always a nice little pick me up.
seriously, the extreme was a decent upgrade, imo. but the stuff was just too damn expensive. i bought some stoked and ran it with reg 6oxo, not bad but not as good as the extreme.
ahem, look again. a bottle=60 caps, dosing is 5 caps 2xday. that's 6 days worth. and believe it or not but the price has came down, i paid more than that for it,lol.:dunno:
hey man, take that crap over to the juvenile forum.
Yes it will, actually some people put it in vodka and take it sublingual.Will it dissolve in a medium like ethanol?
I'm not a chemist by any means so hopefully a veteran of the chemical world will have to chime in soon
Over at imminst the general idea seems to be sublingual is the easiest way to get decent plasma levels.
I'm taking 2 x 300mg orally (because it came out that way capped) but I make sure I get my copper in. I take it with shilajit (black indian) which supposedly can increase uptake. I do notice a little extra energy boost this way. The combination does increase stamina/endurance noticably.
good info, what other effects have you had besides the stamina/endurance-not that that isn't good enough. how long have you been taking?Yes it will, actually some people put it in vodka and take it sublingual.
Over at imminst the general idea seems to be sublingual is the easiest way to get decent plasma levels.
I'm taking 99% bulkpowder, capped it for convenience.
If taking orally for "life extension" 5 mg/kg bodyweight has been used in some studies with increased lifespan as result.
There seem to be issues with taking too high doses, achilles tendoitis, presumably because Resveratrol is a copper chelator, depletes copper from your body, and sore joints.
There are some studies on quercetin increasing resveratrol bioavailability by using up enzymes in some conversion process in the liver increasing plasma levels of resv and extending half life quite a bit, but there's also some controversial study on quercetin to block some of resveratrols effects (sirt1 activation), although in other studies quercetin activates sirt1 on its own. However from m&m feedback some people develop depressions on quercetin or lose libido.
IOW nobody knows exactly
These are the only effects I'm sure off, my skin does seem to look better and my eyes look brighter but I also got some sun recently so I simply cannot attest that to Resv.
link in pm.
There are numerous reports on this on the imminst forum. Maybe you should supplement with copper. But I dont know if that helps the issue, just speculating..
On a serious note, has anyone tried suppository delivery? I mean, it is a legitimate way to deliver meds into the system.
Yeah, good price too I think, if you take the recommended 5mg / kg bw, so 400-500mg a day, 100 grams will almost last a year. Comes out to maybe 10-12 GBP a month?Cheers mate, shame ethanol would taste like crap
There's a thought
That is a thought certainly. However would it be worth taking this as a 'staple' supplement or would a cyclic fashion be more beneficial?Yeah, good price too I think, if you take the recommended 5mg / kg bw, so 400-500mg a day, 100 grams will almost last a year. Comes out to maybe 10-12 GBP a month?
Ofcourse the bio-availability is still an issue nobody has a real good answer too. Some research needs te be done what happens to the metabolites of resv, some suggest they get converted back to resv in target tissues, which would mean that there is no bio-availability issue at all.. Other theories are the metabolites are actually active themselves. If you would be taking Resv purely for anti-tumor purposes and the metabolites are doing nothing you would need to take like 5 grams of bulkpwder a day.
There's a thought
What purpose are you taking it for?
I think it's worth it as a staple. You can buy it at decent prices in bulk. I would take it for the possible Sirt1 activation alone. Seems bioavailability is enhanced even more taking it dissolved in lecithin.Keeping oestrogen under control and all the associated benefits outlined in that excellent thread you posted a link to
Yeah, unless..
It's not that big as a sport performance enhancement product as of yet, although it does have a noticable impact on endurance for me, others have also reported on this. There are some products using it as a natural SERM also. Hard to say how effective it is at that. Lets say it did not come anywhere close for me combatting gynoish issues as some well known and tried SERMs.
Selective Estrogen Receptor Modulator, such as tamoxifen or clomiphene citrate. A substance that blocks the activity of estrogen in some bodily tissues by displacing it at the receptor. Very helpful if you don't want excess estrogen to affect things like breast tissue for example.
Instead of bulk resveratrol powder, you should try resveratrol melts. It's still buccal delivery resveratrol (like sublingual), but as oppposed to the sublingual resveratrol, it does not get lumped up and dissolves quickly with a pleasant feeling and great taste. ezmelts has the highest dosage buccal delivery resveratrol in the market at 150 mg per daily dose. That should provide the greater bioavailability you are looking for. I take them almost like candy, one 75mg resveratrol tablet after every meal / snack.
| Thread starter | Similar threads | Forum | Replies | Date |
|---|---|---|---|---|
| Diet for lean bulk | Nutrition / Health | 2 | ||
| hydration during the bulk | Nutrition / Health | 1 | ||
| Resveratrol on a bulk - any anecdotal reports? | Supplements | 6 | ||
|
Resveratrol bulk | Supplements | 1 | |
| Bulk Trans-resveratrol Dosing? | Supplements | 5 |
