"Stimulant Break" Necessary, Science or BroScience?

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  1. Quote Originally Posted by john A. View Post
    Adrenal Blowout is bs? Well, let me tell you that when the adrenal glands don't function properly it's called Addison disease. Thus, although your mates take stim for up to 3 months what they don't realize is the fact that if they continue is that it leads to high cortisol levels. I myself personally can't do the constant intake of caffeine & pre-workouts for that long of a time period as your mates have. I usually take a break from the stims. But, I as well use to take take pre-workouts 3-4 days at a time a week (range from 200mg-300mg). It had gotten to a point where the pwo wern't working for me at all & I would drink a high carb protein shake 45 min before taking my pre-workout just to give me that extra perk of energy in the gym. I've taken an assortment of various one's, also it depends on how much caffeine and other stims are contained in a pre-workout. For instance I once had a sample of Razor8 which contains 400mg of caffeine & it didn't do squat for me at all.
    ADDISONS DISEASE IS RARE. ARE YOU SERIOUS?! You just dont devlop addisons disease, it is a deficiency in your endocrine system where it can not produce hormones such as glucocorticodes. dude you need to read into things more before posting. addisons is VERY rare.


  2. Quote Originally Posted by EatMoar View Post
    ADDISONS DISEASE IS RARE. ARE YOU SERIOUS?! You just dont devlop addisons disease, it is a deficiency in your endocrine system where it can not produce hormones such as glucocorticodes. dude you need to read into things more before posting. addisons is VERY rare.
    Being ADHD I can confirm that you won't get Addison's from long term stim use... 2 years is my longest with out any break from methylphenidate...it still works but I do take breaks from it more often now...



    And before some says cool I can take stims for years based on my post the answer is no, you simply can't its not healthy...
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  3. Quote Originally Posted by harbonah View Post
    Being ADHD I can confirm that you won't get Addison's from long term stim use... 2 years is my longest with out any break from methylphenidate...it still works but I do take breaks from it more often now...



    And before some says cool I can take stims for years based on my post the answer is no, you simply can't its not healthy...
    Probably not healthy but my parents have drunken cups of coffee every single day for over 30 years with no adverse effects

  4. Quote Originally Posted by horizons View Post
    Probably not healthy but my parents have drunken cups of coffee every single day for over 30 years with no adverse effects
    There are many health benefits from coffee so I doubt they would have anything to worry about at all.

    Nice to see another Aussie on the boards.
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  5. Quote Originally Posted by john A. View Post
    Hello Horizons, The answer to your question is yes taking 1 week off a month from taking a break from stimulants. What happens is the body becomes so immune to the stimulants from caffeine or caffeine containing pre-workouts that they essentially stop working due to the adrenal glands working overtime & the fact it can damage your adrenal glands by literally blowing them out. Also, if you need a product to get your adrenal glands back to normal a must look into product from CTDLABS is Adrenal Reset this will help your adrenal glands back to normal as well as build your immune system, cheers
    Get out of here with your junk. Adrenal fatigue is not real.
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  6. Basically you misread what I wrote. What I stated was when the adrenal glands a.) shut down totally and b.) don't produce enough cortisol and/or aldosterone it can occur. Actually two forms of it, maybe I should've defined it a little better as adrenal insufficiency (fatigue). Anyway everyone's body reacts to certain stims different than others which merits the fact as I stated in my post that I personally do take breaks from stimulant pre-workouts etc. Pure plan and simple too much of anything will cause sometime to occur. Yet, stims basically fool the adrenal glands to put out more adrenaline which eventually for long-term usage can lead one to dependence, as the adrenals down-regulate and function poorly without the use of a stimulant.
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  7. Quote Originally Posted by john A. View Post
    Basically you misread what I wrote. What I stated was when the adrenal glands a.) shut down totally and b.) don't produce enough cortisol and/or aldosterone it can occur. Actually two forms of it, maybe I should've defined it a little better as adrenal insufficiency (fatigue). Anyway everyone's body reacts to certain stims different than others which merits the fact as I stated in my post that I personally do take breaks from stimulant pre-workouts etc. Pure plan and simple too much of anything will cause sometime to occur. Yet, stims basically fool the adrenal glands to put out more adrenaline which eventually for long-term usage can lead one to dependence, as the adrenals down-regulate and function poorly without the use of a stimulant.
    And you would be totally wrong. Addison's disease is not caused by the inability of the adrenal glands to function. It causes the inability of the adrenal glands to function.

  8. Quote Originally Posted by john A. View Post
    Hello Horizons, The answer to your question is yes taking 1 week off a month from taking a break from stimulants. What happens is the body becomes so immune to the stimulants from caffeine or caffeine containing pre-workouts that they essentially stop working due to the adrenal glands working overtime & the fact it can damage your adrenal glands by literally blowing them out. Also, if you need a product to get your adrenal glands back to normal a must look into product from CTDLABS is Adrenal Reset this will help your adrenal glands back to normal as well as build your immune system, cheers
    ^this post just blew out my adrenal glands

  9. So the consensus seems to be that stimulants do not cause adrenal fatigue... But is adrenal fatigue an actual condition caused by other factors other than stimulant use?

  10. Quote Originally Posted by Synthesis View Post
    So the consensus seems to be that stimulants do not cause adrenal fatigue... But is adrenal fatigue an actual condition caused by other factors other than stimulant use?
    Correct, the main reason to cycle stimulants is to reduce tolerance.

  11. Quote Originally Posted by gmanall View Post
    Correct, the main reason to cycle stimulants is to reduce tolerance.
    So what are these factors? Would help bring some clarity to the discussion

  12. Quote Originally Posted by Synthesis View Post
    So what are these factors? Would help bring some clarity to the discussion
    To quote coop:If you don't feel stims, it is due to peripheral receptor downregulation.

    So it'd seem tolerance is not depleting your body of something, causing adrenal fatigue or anything of that nature. It's your body building a tolerance to something it's exposed to on a regular basis.

  13. Quote Originally Posted by Synthesis View Post
    So the consensus seems to be that stimulants do not cause adrenal fatigue... But is adrenal fatigue an actual condition caused by other factors other than stimulant use?
    Yea, the "other factor" has been mentioned about a hundred times in this thread.

  14. Quote Originally Posted by gmanall View Post
    To quote coop:If you don't feel stims, it is due to peripheral receptor downregulation.

    So it'd seem tolerance is not depleting your body of something, causing adrenal fatigue or anything of that nature. It's your body building a tolerance to something it's exposed to on a regular basis.
    I don't think I have articlulated my point clearly enough... So I'll try again

    Quote Originally Posted by mmats View Post
    Yea, the "other factor" has been mentioned about a hundred times in this thread.
    Addisons disease was mentioned in this thread as a vary rare autoimmune disease that causes the adrenal gland to not function properly... So addisons disease does not corelate with the multitude of claims of people who say they have experienced adrenal fatigue... what I'm trying to ascertain is are there any other factors that are responasable for the symptoms thst people have labeled as adrenal fatigue... because Addison's is defitnalty not adrenal fatigue... People have claimed to have recovered from adrenal fatigue swiftly through the use of adaptogens, licorce extract, adrenal bovine etc... None of that sh*t could help treat addisons... So what are the proponents of the adrenal fatigue diagnosis, actually diagnosing? What are people who claimed to have suffered from adrenal fatigue actually experiencing?


    From the mayo clinic site:

    Proponents of the adrenal fatigue diagnosis claim this is a mild form of adrenal insufficiency caused by chronic stress. The unproven theory behind adrenal fatigue is that your adrenal glands are unable to keep pace with the demands of perpetual fight-or-flight arousal. As a result, they can't produce quite enough of the hormones you need to feel good. Existing blood tests, according to this theory, aren't sensitive enough to detect such a small decline in adrenal function but your body is.

  15. Quote Originally Posted by Synthesis View Post
    I don't think I have articlulated my point clearly enough... So I'll try again



    Addisons disease was mentioned in this thread as a vary rare autoimmune disease that causes the adrenal gland to not function properly... So addisons disease does not corelate with the multitude of claims of people who say they have experienced adrenal fatigue... what I'm trying to ascertain is are there any other factors that are responasable for the symptoms thst people have labeled as adrenal fatigue... because Addison's is defitnalty not adrenal fatigue... People have claimed to have recovered from adrenal fatigue swiftly through the use of adaptogens, licorce extract, adrenal bovine etc... None of that sh*t could help treat addisons... So what are the proponents of the adrenal fatigue diagnosis, actually diagnosing? What are people who claimed to have suffered from adrenal fatigue actually experiencing?


    From the mayo clinic site:

    Proponents of the adrenal fatigue diagnosis claim this is a mild form of adrenal insufficiency caused by chronic stress. The unproven theory behind adrenal fatigue is that your adrenal glands are unable to keep pace with the demands of perpetual fight-or-flight arousal. As a result, they can't produce quite enough of the hormones you need to feel good. Existing blood tests, according to this theory, aren't sensitive enough to detect such a small decline in adrenal function but your body is.
    You believe people on the internet who self diagnose themselves with adrenal fatigue and then cure it with adaptogens. That is neat

  16. I see a ton of people on here and ask for medical advice instead of going to the doctor. What's even worse is people reply to them, telling them to self-medicate with supplements. I don't understand that. When I have a medical issue, the last place I want to ask questions is an internet message board.

  17. Quote Originally Posted by Synthesis View Post



    Addisons disease was mentioned in this thread as a vary rare autoimmune disease that causes the adrenal gland to not function properly... So addisons disease does not corelate with the multitude of claims of people who say they have experienced adrenal fatigue... what I'm trying to ascertain is are there any other factors that are responasable for the symptoms thst people have labeled as adrenal fatigue... because Addison's is defitnalty not adrenal fatigue... People have claimed to have recovered from adrenal fatigue swiftly through the use of adaptogens, licorce extract, adrenal bovine etc... None of that sh*t could help treat addisons... So what are the proponents of the adrenal fatigue diagnosis, actually diagnosing? What are people who claimed to have suffered from adrenal fatigue actually experiencing?
    The only thing I can think of is the acute stress/increased anxiety stimulants can cause to those who are stim sensitive is what people refer to as "adrenal fatigue". Doing a full .2mg/kg dose of yohimbine will give a good amount of people high anxiety, this combined with ordinary daily stress will surely give them a feeling of lethargy and irritability, and over a week would cause a significant amount of stress. I assume the help from adaptogens comes from lowering the perceived amount of stress they feel (which is generally heightened by the stims) and also the physical response to stress. This leads to people feeling normal, energized, happy, etc...

  18. The .2mg/kg dose of yohimbine...Shouldn't that be spread out throughout the day instead of taken all at one time?.

  19. Quote Originally Posted by T-Bone View Post
    The .2mg/kg dose of yohimbine...Shouldn't that be spread out throughout the day instead of taken all at one time?.
    I've always used that as 1 dose. I'm about 100kg so I do 20mg along with 200mg of caffeine when I use it. I may do that 2-3 times a day if I know I'll be fasted, otherwise 1 morning dose.. Yohimbine loses its effect on me pretty fast, so I don't feel stimmed out after the first few days.

  20. Quote Originally Posted by mmats View Post
    You believe people on the internet who self diagnose themselves with adrenal fatigue and then cure it with adaptogens. That is neat
    On the contrary... I do not believe the adrenal fatigue diagnosis... I am just relaying other peoples thoughts and experiences in order to get a deeper understanding of this matter

    Quote Originally Posted by T-Bone View Post
    I see a ton of people on here and ask for medical advice instead of going to the doctor. What's even worse is people reply to them, telling them to self-medicate with supplement s. I don't understand that. When I have a medical issue, the last place I want to ask questions is an internet message board.
    Couldn't agree more... but technically adrenal fatigue is not recognised by the medial community so this issue does not present itself in this case

    Quote Originally Posted by BlackWinging View Post
    The only thing I can think of is the acute stress/increased anxiety stimulants can cause to those who are stim sensitive is what people refer to as "adrenal fatigue". Doing a full .2mg/kg dose of yohimbine will give a good amount of people high anxiety, this combined with ordinary daily stress will surely give them a feeling of lethargy and irritability, and over a week would cause a significant amount of stress. I assume the help from adaptogens comes from lowering the perceived amount of stress they feel (which is generally heightened by the stims) and also the physical response to stress. This leads to people feeling normal, energized, happy, etc...
    Thanks for your input... So again you would say it boils down to an issue of tolerance but in this case individuals who are sensitive to stims... who probably would be better off without them

  21. Quote Originally Posted by lronFist View Post
    ^this post just blew out my adrenal glands
    This is the real mechanism of adrenal fatigue. The adrenal glands get blown out of your body like an ejector seat.
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  22. Quote Originally Posted by bdcc View Post
    This is the real mechanism of adrenal fatigue. The adrenal glands get blown out of your body like an ejector seat.
    Nah, its caused by the extreme stress of cooking shellfish.



  23. Quote Originally Posted by mmats View Post
    Nah, its caused by the extreme stress of cooking shellfish.
    LOL

  24. If adrenal fatigue is as bad or as common as some people pan it out to be here on AM then I should be the poster boy for it ( for the record it's being blown totally out of proportion ) and with that being said there are way way more stressors in life than just putting stimulants in your body that can cause these so called symptoms of adrenal fatigue.

    T-bone nailed it with the first post.

  25. Quote Originally Posted by Synthesis View Post
    IExisting blood tests, according to this theory, aren't sensitive enough to detect such a small decline in adrenal function — but your body is.
    That is the dumbest thing I've ever heard.
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