New DAA Study

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    New DAA Study


    d-Aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo-pituitary-gonadal axis in resistance-trained men

    Odd given the study showing it did have an effect, and the plethora of people who have done bloodwork on themselves.

    But, I generally trust a study that come out of the Baylor HPL.
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    I disagree.
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    Interesting. Perhaps it is the age difference? The Topo et al study used men 27-37 while this when used men 18-23. It is possible that the T levels for the men in this study were already in the upper range so DAA didnt make as much of an impact as it did for the other study.
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    Quote Originally Posted by T-Bone View Post
    I disagree.
    What is it you disagree with? Please elaborate what exactly in this study it is that you have a problem with
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    Quote Originally Posted by JudoJosh View Post
    Interesting. Perhaps it is the age difference? The Topo et al study used men 27-37 while this when used men 18-23. It is possible that the T levels for the men in this study were already in the upper range so DAA didnt make as much of an impact as it did for the other study.

    That makes sense. DAA is pretty dramatic as far as results go when I take it. I turned 41 last month.
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    Quote Originally Posted by JudoJosh View Post
    What is it you disagree with? Please elaborate what exactly in this study it is that you have a problem with
    I disagree with what is printed in red in the first post.
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    Someone get me the full text please. It's plausible that the fact that DAA didn't even significantly increase plasma levels is indicative of the fact that bulk DAA has a very poor bioavailability (vs the sodium DAA in the 42% study). But idk if they used sodium DAA here...coop@pescience.com would like the FT though
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    Quote Originally Posted by mr.cooper69 View Post
    Someone get me the full text please. It's plausible that the fact that DAA didn't even significantly increase plasma levels is indicative of the fact that bulk DAA has a very poor bioavailability (vs the sodium DAA in the 42% study). But idk if they used sodium DAA here...coop@pescience.com would like the FT though
    I sent it mr.Statistics69
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    Got it, thanks. The study looks very well-conducted. One thing I will say is that the effect of DAA on LH, while not statistically significant, appears to be considerable, especially since GnRH decreased in both groups. So another theory for these results is that 1 month of supplementation allows adequate homeostatic compensation to occur in response to increased LH release by DAA. But again, just a theory
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    Quote Originally Posted by mr.cooper69 View Post
    bulk DAA has a very poor bioavailability (vs the sodium DAA in the 42% study). But idk if they used sodium DAA here...
    Considering that solubility of aminos is a function of pH, there really shouldn't be a difference in DAA vs sodium d-aspartate.

    I messaged you some additional thoughts on this
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    Quote Originally Posted by mr.cooper69 View Post
    Someone get me the full text please. It's plausible that the fact that DAA didn't even significantly increase plasma levels is indicative of the fact that bulk DAA has a very poor bioavailability (vs the sodium DAA in the 42% study). But idk if they used sodium DAA here...coop@pescience.com would like the FT though
    Guess that's why TCF 1 works so good huh? The delivery system
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    Quote Originally Posted by JudoJosh View Post
    Considering that solubility of aminos is a function of pH, there really shouldn't be a difference in DAA vs sodium d-aspartate.

    I messaged you some additional thoughts on this
    Except that ionic bonding to sodium or chelation with Mg/Ca results in a salt or chelate, not an amino acid
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    Quote Originally Posted by JD261985 View Post
    Guess that's why TCF 1 works so good huh? The delivery system
    More the form (sodium) than delivery, but yes, homogenization does help
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    Once DAA is dissolved in water the pH of minimum solubility is about pH 3.0 and once it enters the stomach it is neutralized to about a pH of 7-8 at which point DAA should become pretty damn soluble.

    Yes the sodium bonding changes the solubility but this is its solubility in water, not the gut. Once DAA enters the gut the lack of solubility in water at a neutral pH really becomes irrelevant when we are discussing bioavailability and absorption, does it not? I honestly dont see why this should matter
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    Interesting discussion! I'll tag along.
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    Quote Originally Posted by JudoJosh View Post
    Once DAA is dissolved in water the pH of minimum solubility is about pH 3.0 and once it enters the stomach it is neutralized to about a pH of 7-8 at which point DAA should become pretty damn soluble.

    Yes the sodium bonding changes the solubility but this is its solubility in water, not the gut. Once DAA enters the gut the lack of solubility in water at a neutral pH really becomes irrelevant when we are discussing bioavailability and absorption, does it not? I honestly dont see why this should matter

    I don't follow this post. The pH of a DAA solution is neutralized in the stomach?
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    Quote Originally Posted by mr.cooper69 View Post

    More the form (sodium) than delivery, but yes, homogenization does help
    Is DAA magnesium chelate stronger than sodium DAA?
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    Quote Originally Posted by JD261985 View Post
    Is DAA magnesium chelate stronger than sodium DAA?
    I'm not sure. It has less DAA per gram, but I'd expect the total uptake to be a tad higher
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    Quote Originally Posted by T-Bone View Post
    I disagree with what is printed in red in the first post.
    That was just the title of the paper not my thoughts just to be certain
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    This is horribly written!

    "Because there are data supporting the role of D-ASP supplementation in increasing endogenous testosterone levels, this amino acid product may prove beneficial as a means in which to increase muscle performance associated with heavy resistance training. However, because there appears to be a paucity of human studies dealing with D-ASP supplementation, and apparently none when D-ASP is ingested in conjunction with resistance training, we hypothesized that D-ASP would not increase endogenous testosterone levels or improve muscular performance associated with resistance training."
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    Who wants to be a jolly good fellow and send me the FT as well please?
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    So have we arrived at a consensus about DAA then?
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    I'm kind of surprised at the little increase of hormones compared to the 42% study, but not surprised at all in the other results. I've enjoyed DAA outside of GI issues, but testing strength and muscle mass...I mean isn't that more of a exogenous hormone thing and not a natural test booster thing?

    I can only see the abstract so I can't see all the details.
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    I'd like to read the FT as well. Any body have a link to it the FT article?
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    Quote Originally Posted by T-Bone View Post
    That makes sense. DAA is pretty dramatic as far as results go when I take it. I turned 41 last month.
    I believe this is the main aspect. The lower you are the more affect it may have.
    I definitely notice when I am using DAA personally. I run on the lower end of normal in my levels, though I feel great and have no symptoms.
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    Quote Originally Posted by mcc23 View Post
    So have we arrived at a consensus about DAA then?
    A single study definitely doesn't make a consensus. It's an interesting study though.
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    On a similar note I know of a similar study going on right now that will be peer reviewed and published, hopefully by the end of the year......
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    Quote Originally Posted by Grambo View Post
    On a similar note I know of a similar study going on right now that will be peer reviewed and published, hopefully by the end of the year......
    On D-pol, no?
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    Quote Originally Posted by mr.cooper69 View Post
    On D-pol, no?
    Yep you got it. Should be pretty interesting.
    They were excited about it this weekend while I was helping out with the Dallas Europa.
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    Quote Originally Posted by Grambo View Post

    Yep you got it. Should be pretty interesting.
    They were excited about it this weekend while I was helping out with the Dallas Europa.
    Speaking of the Europa; did you save me a shirt like I asked?!?
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    Quote Originally Posted by jimbuick View Post
    Speaking of the Europa; did you save me a shirt like I asked?!?
    I didn't even get a shirt! They threw them all into the crowd/shirt cannon before I could get my hands on one

    I do have a bunch of extras of the new shirts. What size?
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    Quote Originally Posted by Grambo View Post

    I didn't even get a shirt! They threw them all into the crowd/shirt cannon before I could get my hands on one

    I do have a bunch of extras of the new shirts. What size?
    That's ridiculous.


    XL.
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    Ive been looking at those black EL/ST shirts for a while, and the new grey looks awesome.

    Hopefully, I can afford to get some soon to go with my red one.
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    Quote Originally Posted by jimbuick View Post
    Ive been looking at those black EL/ST shirts for a while, and the new grey looks awesome.

    Hopefully, I can afford to get some soon to go with my red one.
    I have an XL in each ill hook it up. PM me
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    Quote Originally Posted by Grambo View Post
    I believe this is the main aspect. The lower you are the more affect it may have.
    I definitely notice when I am using DAA personally. I run on the lower end of normal in my levels, though I feel great and have no symptoms.
    I won some DAA from Allmax the other day but after reading the study (and Coop's opinion regarding it) I think I won a tub of Placebo powder
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    Also interested in the FT. Anybody have additional details they can provide?

    Tx
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    Quote Originally Posted by MonteCedillo View Post
    I'd like to read the FT as well. Any body have a link to it the FT article?
    Quote Originally Posted by sdunlimited View Post
    Also interested in the FT. Anybody have additional details they can provide?

    Tx
    Josh sent it to me so I have it. Send me your email addresses.
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    Quote Originally Posted by bdcc View Post

    Josh sent it to me so I have it. Send me your email addresses.
    Thanks Ben!
  

  
 

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