[h=2]Potential Role of Branched Chain Amino Acid (BCAA) Catabolism in Regulating Fat Oxidation.[/h][h=3]Abstract[/h]Insulin resistant or obese individuals have increased serum BCAA levels. Recent findings relate increased BCAA catabolism to increased fatty acid oxidation and better metabolic health in physically active individuals. We hypothesize that via glyceroneogenesis, BCAA catabolism mediates increased constitutive use of fatty acids for β-oxidation in subjects with increased inherent or acquired aerobic capacity both during exercise and at rest.Summary for the table of contentsThis article presents the hypothesis that skeletal muscle BCAA catabolism mediates increased constitutive use of fatty acids for β-oxidation.
PMID: 23873132