Chromosomal Damage Induced by AAS study article

[Nightwanderer]

http://www.aensi.org/aeb/2007/39-43.pdf

The number of abnormal cells with CAs was
insignificantly low at treatment doses of 1, 10, 20
mM, respectively, for both steroids being tested for
genotoxicity, in the presence as well as absence of
metabolic activation i.e. S9 mix (Tables 1 and 2). A
dramatic increase in genotoxic damage was noticed
when the dosage was increased to 40 and 60 mM. At
this dosage level, the abnormal cells more than
doubled, although the dose-dependent increase in
CAs was small from 40 to 60 mM.