Clen's anticatibolic abilities?

[pistonpump]

Do you guys believe that Clenbuterol can assist in preserving muscle? I have read that it helps with anti-catabolism but some people say otherwise. What are your opinions on its use in PCT to keep gains?

 

[jminis]

No I don't believe it does so in humans. Pigs maybe

 

[pistonpump]

No I don't believe it does so in humans. Pigs maybe

and this is your thoughts based on experience right? Do you think its a bad idea in Postcycle?

 

[blackheart]

There is good science behind the use of Albuterol in humans -- Placebo-controlled, double blind, crossover studies -- and (of course) plenty in lower animals, though IMO you shouldn't infer much from those. I would avoid Clen due to the heart health risks.

 

[jonny21]

No I don't believe it does so in humans. Pigs maybe

Horses actually. They use it to keep them toned.

 

[jminis]

lol sorry horses. Based on experience and knowing countless others who've used clen. If you want to take it for fatloss it will def help during PCT. If you main objective is anti catabolic don't waste your time.

 

[pistonpump]

lol sorry horses. Based on experience and knowing countless others who've used clen. If you want to take it for fatloss it will def help during PCT. If you main objective is anti catabolic don't waste your time.

i was hoping for both. i was going to use the injectable helio's....maybe ill start them 4th week in pct so that i dont shrink too much haha.

 

[MentalTwitch]

It is in mice/rats too. They have an enzyme we lack, so i was told previosuly. That is why it is not anticatabolic for us.

 

[blackheart]

*sigh*

What I said the first time -- Search yourself if you need more evidence, there's literally thousands of studies that support Albuterol IN HUMANS.

J Strength Cond Res. 2005 Feb;19(1):102-7.Links
Oral albuterol dosing during the latter stages of a resistance exercise program.
Caruso JF, Hamill JL, De Garmo N.
Healthcare Research Associates Inc., Orlando, Florida 32819, USA.

Aviat Space Environ Med. 2004 Jun;75(6):505-11.Links
Albuterol helps resistance exercise attenuate unloading-induced knee extensor losses.
Caruso JF, Hamill JL, Yamauchi M, Mercado DR, Cook TD, Keller CP, Montgomery AG, Elias J.
Exercise Physiology Laboratory, University of Nevada, Reno, NV, USA

Caruso J, Hamill J, Yamauchi M, Mercado D, Cook T, Higginson B, O'Meara S, Elias J, Siconolfi S.
Albuterol aids resistance exercise in reducing unloading-induced ankle extensor strength losses.
J Appl Physiol. 2005 May;98(5):1705-11. Epub 2005 Jan 7.
PMID: 15640389 [PubMed - indexed for MEDLINE]

Albuterol increases lean body mass in ambulatory boys with Duchenne or Becker muscular dystrophy.
Neurology. 2008 Jan 8;70(2):137-43. Epub 2007 Oct 17.
PMID: 17942817 [PubMed - indexed for MEDLINE]

Randomized, double-blind, placebo-controlled trial of albuterol in facioscapulohumeral dystrophy.
Neurology. 2001 Oct 23;57(8):1434-40.Click here to read Links
Kissel JT, McDermott MP, Mendell JR, King WM, Pandya S, Griggs RC, Tawil R; FSH-DY Group.
Department of Neurology, The Ohio State University, Columbus, 43210, USA.

Uc EY, Lambert CP, Harik SI, Rodnitzky RL, Evans WJ.
Abstract
Albuterol improves response to levodopa and increases skeletal muscle mass in patients with fluctuating Parkinson disease.
Clin Neuropharmacol. 2003 Jul-Aug;26(4):207-12.
PMID: 12897642 [PubMed - indexed for MEDLINE]

Neurology. 2002 Aug 27;59(4):609-10.
Pilot trial of albuterol in spinal muscular atrophy.
Kinali M, Mercuri E, Main M, De Biasia F, Karatza A, Higgins R, Banks LM, Manzur AY, Muntoni F.
Department of Paediatrics, Dubowitz Neuromuscular Centre, Imperial College School of Medicine, London, United Kingdom.

Caruso JF, Hamill JL, Yamauchi M, Cook TD, Mercado DR, Gibb G, Higginson BK, Elias J, Hernandez DA.
Abstract
Can albuterol help resistance exercise attenuate unloading-induced bone loss?
J Strength Cond Res. 2004 Nov;18(4):753-9.
PMID: 15574079 [PubMed - indexed for MEDLINE]

van Baak MA, Mayer LH, Kempinski RE, Hartgens F.
Abstract
Effect of salbutamol on muscle strength and endurance performance in nonasthmatic men.
Med Sci Sports Exerc. 2000 Jul;32(7):1300-6.
PMID: 10912897 [PubMed - indexed for MEDLINE]

OK, I'm bored now, but I'm sure you catch my drift now...

 

[crader]

I have always retained muscle while using clen.

 

[pistonpump]

thanks crader.

 

[MentalTwitch]

The thread is about Clen. So he wants to know about Clen. Clen is stronger yes and not for the weak, but worht it as i hear right now....

 

[russianstar]

actualy, clen is awsome at preserving muscle, just keep protein intake high, and remember its small anabolic ability diminishes after 3 weeks,but its fat burning ability works on me for about 4 and a half weeks in general, i cycle 4 on 2 off, works well for me, i start at 40 mcg and depending on how i feel increase slowly until 80 mcg ed,

Clenbuterol
Clenbuterol is a widely used bronchodilator in many parts of the world. It is most often prepared in 2Omcg tablets, but Clenbuterol is also available in syrup and injectable form. This drug belongs to a broad group of drugs knows as sympathomimetics. Clenbuterol affect that sympathetic nervous system in a wide number of ways, largely mediated by the distribution of adrenoceptors.

Use of Clenbuterol
The drug is specifically a selective beta-2 sympathomimetic, primarily affecting only one of the three subsets of beta-receptors. Of particular interest is the fact that Clenbuterol has little beta-i stimulating activity. Since beta-i receptors are closely tied to the cardiac effects of adrenoceptors, this allows to reduce reversible airway obstruction (and effect of beta-2 stimulation) with much less cardiovascular side effects compared to non-selective beta agonists. Clinical studies with Clenbuterol show it is extremely effective as a bronchodilator, with a low level of user complaints and high patient compliance Clenbuterol also exhibits an extremely long half-life in the body, which is measured to be approximately 34 hours long. This makes steady blood levels easy to achieve, requiring only a single or twice daily dosing schedule at most. This of course makes it much easier for the patient to use, and may tie into its high compliance rate. To spite that Clenbuterol is available in a wide number of other countries however; Clenbuterol has never been approved for use in the United States. The fact that there are a number of similar to Clenbuterol, effective asthma medications already available in this country may have something to do with this, as a prospective drug firm would likely not find it a profitable enough product to warrant undergoing the expense of the FDA approval process. Regardless, foreign Clenbuterol preparations are widely available on the U.S. black market.

How Clenbuterol Works
Clenbuterol is shown to stimulate fat cells to breakdown and form free fat acids, thus increasing your metabolism. It will also increase muscle strength, by allowing more oxygen to be used by cells that need it. Fat brake down process will keep your body temperature slightly over normal (half of a degree or so). These properties make Clenbuterol an excellent choice, if your goal is to reduce your overall body fat.

Debate over Clenbuterol
In animal studies Clenbuterol is shown to exhibit anabolic activity , obviously an attractive trait to the athlete. The drug is additionally a known thermogenic with beta-2 agonists shown to directly stimulate fat cells and accelerate the breakdown of triglycerides to form free fatty acids. Its efficacy in this area makes Clenbuterol a very attractive, and today almost mandatory, pre-contest drug. Those interested in Clenbuterol are most often hoping it will impart a little of both benefits, promoting the loss of body fat while imparting strength and muscle mass increases. But as was well pointed out by a review published in the August 1995 issue of Medicine and Science in Sports and Exercise, the possible anabolic activities in humans are very 9 and based only on animal data using much larger doses than would be required for bronchodilation. With such reports there has been a lot of debate concerning Clenbuterol lately as to whether or not Clenbuterol is really anabolic at all. Some seem to swear by the fact that Clenbuterol builds muscle regardless, firmly sticking by "den" as a great off-season or adjunct anabolic. To others such reports are confirmation that athletes have wasted valuable time and money on drugs that do not work as they are intended to by the user.

Clenbuterol and fat loss
When using Clenbuterol for fat loss , the primary effect of Clenbuterol, it seems to work well for approximately 4-6 weeks. During this period, users will want to constantly monitor their body temperature. We are assured Clenbuterol is working by the temperature elevation. Once the temperature drops back to normal, this drug is no longer exhibiting a thermogenic effect. At this point increasing the dosage would not be very effective, and a break for at least a few weeks should be taken before it is used again effectively. If one is looking for strength gains, it appears to be effective for a much shorter period of time, around 3-4 weeks. This may be due to an absence of real anabolic effect, with the strength gain seen with Clenbuterol possibly due only to the stimulant properties of the drug (similar to the strength boost seen by Ephedrine users). Again however, this is still debated.

Clenbuterol and Cytomel T3/T4
Many competitors also find the fat burning effect of Clenbuterol can be further enhanced by additional substances. When Clenbuterol combined with thyroid hormones, specifically the powerful Cytomel , the thermogenic effect of Clenbuterol can become extremely dramatic. This can be to a point that the athlete could shred exceptional amounts of extra fat during contest preparations, without a dramatic restriction in calories. A clenbuterol/thyroid mix is also common when using growth hormone, further enhancing the thermogenic and anabolic effect of this therapy.

Adrenoceptor in Clenbuterol
There are actually nine different types of these receptors in the body, which are classified as either alpha or beta and further subcategorized by type number. Depending on the specific affinities of these agents for the various receptors, they can potentially be used in the treatment of conditions such as asthma, hypertension, cardiovascular shock, arrhythmias, migraine headaches and anaphylactic shock. The text Goodman and Gillman's The Pharmacological Basis of Therapeutics 9 Edition does a good job of describing the diverse nature in which these drugs affect the body:"Most of the actions of catecholamines and sympathomimetic agents can be classified into seven broad types: (1) peripheral excitatory action on certain types of smooth muscles such as those in blood vessels supplying the skin, kidney, and mucous membranes, and on the gland cells, such as those of the salivary and sweat glands; (2) a peripheral inhibitonj action on certain other types of smooth muscle, such as those in the wall of the gut, in the bronchial tree, and in blood vessels supplying skeletal muscle; (3) a cardiac excitatory action, responsible for in increase in heart rate and force of contraction; (4) metabolic actions, such as an increase in the rate of glycogenolysis in liver and muscle and liberation of free fatty acids from adipose tissue; (5) endocrine actions, such as modulation of the secretion of insulin, rennin, and pituitary hormones; (6) CNS actions, such as respiratory stimulation and, with some of the drugs, an increase in wakefulness and psychomotor activity and a reduction in appetite; and (7) presynaptic actions that result in either inhibition or facilitation of the release of the neurotransmitters such as such as norepinephrine and acetylcholine."

 

[pistonpump]

russianstar how does that relate to this post, no offense i apprieciate you droppin in but im asking about its anti catabolic properties.

 

[crader]

You dork! Thats what he gave you . Clen is best used for the anti catabolic properties for say 3 weeks. So if you want to add it in for post cycle. Run it for 3 weeks to help preserve muscle.

 

[MuscleBound1337]

I've always retained muscle using clen.. If anything I get a little stronger with it. Maybe i'll finish my bottle during pct when i'm done with my cycle.

 

[russianstar]

thanks crader, glad somone understood me, lol maybe its my russian accent?

 

[pistonpump]

lol. okay i read it good this time lol, sorry bud.

crader shutup! lol.

 

[russianstar]

good boy

 

[crader]

You know I never shut up! Its one of my better qualities

 

[SOLARUS]

No I don't believe it does so in humans. Pigs maybe

you are confused. clen is ANABOLIC is pigs, not just anti-catabolic. the anabolism is what cannot be assumed to be applicable to humans.

in my 4 or 5 clen cycles over the years, i always found that it allowed me to retain more muscle than i would have otherwise...i've tried using thyroid hormones w/o it, and it's pretty depressing.

albuterol is anabolic in humans, as shown by a clinical trial out there somewhere....but for me at least, it doesnt strip the fat off like clen does...nor does it make me want to kill myself, either

 

[Hank Vangut]

it seems a lot of old timers use clen in pct. they say it reduces cortisol, maintains strength, and helps maintain muscle mass during low hormone levels.

i found this post from a well known older bber on another board.

Yes. I usually use a moderate dose of clen during my PCT. Without going into a super long explanation, cortisone receptors are created in large numbers during a steroid cycle but cortisone itself is kept at bay by the steroids. So when you stop using the steroids then the cortisone goes nuts in your body, and that leads to a huge increase in cortisol. Cortisol is a stress hormone that can cause muscle breakdown and stop glycogen from being used by the muscle cells.

The point is this, clenbuterol blocks these abundant cortisone receptors and that leads to a lesser amount of cortisol in the body. You don't need to run a full on cycle of clen to get this benefit either. A moderate dose of 40-60mcg during pct can really help the body get back to normal without putting on extra fat or losing your newly gained muscle mass.

 

[pistonpump]

good info guys.

 

[TerribleTowel]

Interesting thread. I've wondered about this myself.

 

[MentalTwitch]

Bump casue i can and i got mine today!!! MAybe ill try it for 3 days before i open my other log.

Also, BUMP for good info. Thats 2 bumps in one post!!:cheers:

 

[HARDtotheCORE]

In my personal experience with clen, i've always noticed a very rapid, very distinct hardness and quality come to my muscles, and i get great pumps while on it. Whether or not this is due to it's anti-catabolic effects i'm not sure, but I was told by a Health care professional who is a very intelligent and very experienced bodybuilder/juicer that it has lots to do with the nutriet repartitioning effects of clenbuterol, not so much it's intrinsic anabolic/anti-catabolic effects.

My biggest complaint on clen was the weird chest pains and the inability to continue with some sets due to the weird feelings in my chest and how it effects breathing/heartrate. This past summer i took clen for a week or so, and hated to stop due to the sides, because i could already see a real difference. The stuff works, but your health and peace of mind is more important imho. - HTTC

 

[SOLARUS]

The stuff works, but your health and peace of mind is more important imho. - HTTC

2nd.

i love clen's effects, but i am immensely uncomfortable when taking it