Hydroxypropyl-Beta Cyclodextrin

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    badbart's Avatar
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    Hydroxypropyl-Beta Cyclodextrin


    Anyone have any experience with using Hydroxypropyl-Beta Cyclodextrin as a penetration enhancer. If taken sublingual absorption is said to be 95%. This would beat transdermal and oral and be almost as effective as injecting. It also looks like a person could mix any steroid or PH into the Hydroxypropyl-Beta Cyclodextrin. If Hydroxypropyl-Beta Cyclodextrin works as good in the real world as on paper I donít see why Hydroxypropyl-Beta Cyclodextrin would not be the ultimate steroid or PH delivery system.

    http://www.avantlabs.com/page.php?pageID=29&issueID=9

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    The problem with it is twofold...
    1. You can only absorb 25 mg of any substance through sublingual delivery at any one time. Not a high enough dose so you need to do it quite a few times a day(and the stuff tastes like ass)
    2. You cannot have eaten anything for the last hour or so before dosing or you lose a significant amount of delivery to saliva. This conflicts withour lifestyleof eating every two hours making it not useless but relatively limited as a delivery system.
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    Originally posted by maggmaster
    The problem with it is twofold...
    1. You can only absorb 25 mg of any substance through sublingual delivery at any one time. Not a high enough dose so you need to do it quite a few times a day(and the stuff tastes like ass)
    2. You cannot have eaten anything for the last hour or so before dosing or you lose a significant amount of delivery to saliva. This conflicts withour lifestyleof eating every two hours making it not useless but relatively limited as a delivery system.
    I did not know this.
    •   
       

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