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Trilostane

  1.  06-29-2007  02:08 PM
    Registered User Hyde12's Avatar
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    Trilostane


    Trilostane: A synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly inhibits 3 beta-hydroxysteroid dehydrogenase delta 5-4 isomerase in the adrenal cortex, resulting in the decreased synthesis of mineralocorticoids and glucocorticoids and the decreased conversion of pregnenolone to progesterone. (NCI04)

    Anyone ever try this? It is used to treat Cushing's syndrome



  2.  06-29-2007  05:12 PM
    Banned Travis's Avatar
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    As what just a cort blocker? Seems like there could be easier ways...

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  3.  06-29-2007  06:14 PM
    Registered User Hyde12's Avatar
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    Yeah, for cortisol.

  4.  06-29-2007  07:37 PM
    Banned Travis's Avatar
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    I read on another forum that your body will adapt to it after about 18 days on. The post was by a board mod and I have no idea about the credibility of the board but they mentioned it wasnt worth the sides.

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