Looking for alt. solvents for oral solutions

[Crazy-Canuck]

I am looking for something a little more easier to take then the current trrend of Peg and 190 proof. I have been reading up on cough syrups to see what they use but I think that these are suspensions and not true solutions and they seem to use Glycerin the impure form of Glycerol. I am looking to make these and not buy them ready made from a source.

My research continues regardless. If anyone has any ideas or can point me in the right direction, I'd be grateful.

Thanks.

CC.

 

[CDB]

I am looking for something a little more easier to take then the current trrend of Peg and 190 proof. I have been reading up on cough syrups to see what they use but I think that these are suspensions and not true solutions and they seem to use Glycerin the impure form of Glycerol. I am looking to make these and not buy them ready made from a source.

My research continues regardless. If anyone has any ideas or can point me in the right direction, I'd be grateful.

Thanks.

CC.

I'm not honestly sure anything else will do for a solution of a methyl. Some are notoriously hard to dissolve into solution as it is. Look at MOHN, the concentration you could reliably get into a soluton was very, very low.

 

[kwyckemynd00]

Superdrol went into olive oil quite nicely at 10mg/mL.

Just heat,stir, and voila.

EDIT: BTW, I had it for like 3 months and it never came out of solution (until it was dropped and lost forever )

 

[Crazy-Canuck]

I'm not honestly sure anything else will do for a solution of a methyl. Some are notoriously hard to dissolve into solution as it is. Look at MOHN, the concentration you could reliably get into a soluton was very, very low.

Yeah, this is the prob I am having. I am looking for evidence of something else that may work. I may be out of luck. If I found anything out, I'll post it though. I may just end up trying a bunch of smaller then usual batches to see if I can get anything to work out. There has to be a way.

CC.

 

[Crazy-Canuck]

Superdrol went into olive oil quite nicely at 10mg/mL.

Just heat,stir, and voila.

EDIT: BTW, I had it for like 3 months and it never came out of solution (until it was dropped and lost forever )

You're supposed to wash your hands after doing that bro!



CC.

 

[bpmartyr]

I just use olive oil for everything. Give it a good shake each time before you draw and the active will suspend and give even dosing. It is cheap, I always have it in stock and it tastes fine.

I know this is not a solution (no pun intended) but it works just as well.

 

[Crazy-Canuck]

Hrm yeah.

Well I am intersted in making pure solutions. While I am sure you are right and I am sure it works fine and certainly easier. I am just trying to do this for myself, more then anything.

Givethe old brain something to do...

CC.

 

[charger]

so you guys using olive oil... your just dumping the powder into the oil. nothing else is used.. BB or BA?

 

[bpmartyr]

so you guys using olive oil... your just dumping the powder into the oil. nothing else is used.. BB or BA?

Dump it in, heat it & shake it.

 

[rhinochaser48]

Try PG.

Patrick Arnold posted something on avant awhile ago about PEG being a poor choice as a solvent. He prefers PG.

I've never tried it though.

 

[jonny21]

so you guys using olive oil... your just dumping the powder into the oil. nothing else is used.. BB or BA?

BA can be used as a preservative @ 2-5%.

 

[FlyByU]

Try PG.

Patrick Arnold posted something on avant awhile ago about PEG being a poor choice as a solvent. He prefers PG.

I've never tried it though.

What's PG?

 

[aspire210]

What's PG?

I think it's propylene glycerol.

 

[Tiftan090]

BA can be used as a preservative @ 2-5%.

BA tastes like crap and makes your tounge numb even at low concentrations, besides, oil keeps pretty well by itself.

 

[aspire210]

BA tastes like crap and makes your tounge numb even at low concentrations, besides, oil keeps pretty well by itself.

Dr. D once said ethyl at 5% was good to keep it sanitary. Doesn't taste near as bad.

 

[DR.D]

Use A relatively unsaturated oil (olive, almond, saff, etc.) with some ethanol. If 190pf is used in place of 200pf, a little PS80 (@~1-2.5%) is a good idea too, or even Lecithin. If a PEG base is used, a 50/50 PEG400/PG works well. I still use about 5% ethanol either way just to enhance solubility and act as a long term bacteriostatic. All of the hydroxylated hormones (diols and M4OHN) are exceptionally hard to solubilize, even with unsaturated oils. Pure Linoleic or Oleic acid works better in such cases, but is not suitable fot IM use (oral only).

 

[flyingjer]

Use A relatively unsaturated oil (olive, almond, saff, etc.) with some ethanol. If 190pf is used in place of 200pf, a little PS80 (@~1-2.5%) is a good idea too, or even Lecithin. If a PEG base is used, a 50/50 PEG400/PG works well. I still use about 5% ethanol either way just to enhance solubility and act as a long term bacteriostatic. All of the hydroxylated hormones (diols and M4OHN) are exceptionally hard to solubilize, even with unsaturated oils. Pure Linoleic or Oleic acid works better in such cases, but is not suitable fot IM use (oral only).

Dr.D so will these suggestions make oral solutions or just good suspensions

 

[DR.D]

Dr.D so will these suggestions make oral solutions or just good suspensions

Suspensions give more stable long term storage. As long as your powder says finely dispersed in the medium and will homogenize smoothly when shaken, why not suspend? Solutions are prettier, but for oral apps there is no real advantage usually, plus the active is often decomposed faster. Also important, suspension don't taste as bad!

 

[flyingjer]

not worried to much about long term storage, i would really just rather have solutions, do you have anyway to do solutions?

 

[DR.D]

not worried to much about long term storage, i would really just rather have solutions, do you have anyway to do solutions?

Yeah, I listed them in post #16.

absolute alcohol
alcohol/oil
alcohol/PG
plain oil
PEG/PG
PEG/H2O/PS80
Linoleic acid
etc...

You need to determine the solubility of the specific substance you want to dissolve, then decide which solvent system is needed and at what ratios. The choices and combos are endless.

 

[flyingjer]

how do i figure out what solvents are best, if you can help me out

i am trying to dissolve

nolva
clomid
t-bol
anavar
cialis
for solutions

 

[flyingjer]

thanks for your help Dr.D in advance i appreciate it, its just i have been working on these for a while and not much success

i was working with gum arabic for a while and you commented on that , but that kept falling out of solution, and when that came out of solution there was a white goo on the bottom of the jar, that would not be resuspended

 

[asap nutrition]

Where can you get PG at a reasonable price? any online sites you guys would suggest

 

[DR.D]

thanks for your help Dr.D in advance i appreciate it, its just i have been working on these for a while and not much success

i was working with gum arabic for a while and you commented on that , but that kept falling out of solution, and when that came out of solution there was a white goo on the bottom of the jar, that would not be resuspended

I'd just use ethanol for all of it. Or you could use a 75:20:5 PEG, EtOH (Everclear), Polysorbate 80 mix.

 

[DR.D]

Where can you get PG at a reasonable price? any online sites you guys would suggest

I'm pretty sure it's all over. I've seen board sponsors or links elsewhere from their sites with it.

 

[kwyckemynd00]

Lemelange.com, an ex sponsor here, has it, and cheap.

They got my package to me in 2-3 days after ordering...

 

[flyingjer]

okay, thought i could get polysorbate 80 at lemeleange, where can i get this?

 

[jonny21]

Run a google search. Look in vitamin shops.

 

[charger]

when mixing with oil-- I assume you can pack alot more mgs/ml. 200mgs/ml then you'd only need a few drops to get down to 5 or 10mgs dose.

Olive oil seams like a good choice since it has some good effects on cholestrol.

 

[Skye]

This is why I don't do this at all any more. its MUCH simpler to make this stuff into candy. I use 60% coco butter chips for anything that would break down fast and the white candy chips from hobby lobby for everthing else.

 

[Rostam]

What about grape seed oil? Do you think it's a good choice? It's not really thick and doesn't taste bad. I used sesam oil in my last batch and the taste was crap.

 

[charger]

This is why I don't do this at all any more. its MUCH simpler to make this stuff into candy. I use 60% coco butter chips for anything that would break down fast and the white candy chips from hobby lobby for everthing else.

ohh please do tell more..

what powders "break down fast"?

what else is used?

 

[flyingjer]

by the way, lemelange got polysorbate 80 again

 

[flyingjer]

okay dr. D. i am going to be purchasing the solvents for my solutions, found the poly 80, one questio is can you use glycerin or PG instead of PEG, isn't glycerin's taste more barable than PEG

 

[DR.D]

okay dr. D. i am going to be purchasing the solvents for my solutions, found the poly 80, one questio is can you use glycerin or PG instead of PEG, isn't glycerin's taste more barable than PEG

Yeah, glycerin is great orally, just don't shoot high concentrations of it (too hygroscopic).

 

[flyingjer]

shoot as in consume? and what is hydroscopic?

 

[jonny21]

shoot as in consume? and what is hydroscopic?

It's hygroscopic: tendency to absorb/attract water.

Like sugar is in baking.

 

[DR.D]

shoot as in consume? and what is hydroscopic?

By 'shoot' I mean subdermal (like an injection). Orally, it tastes kinda sweet and ain't too bad.

 

[flyingjer]

does it cause you to retain water when ingesting it?

 

[DR.D]

does it cause you to retain water when ingesting it?

Yes. It's often used to keep muscles hydrated during DNP cycles.

 

[jarhead]

Would glycerin then be subbed for peg in the same amounts when used with ethyl alchohol recipes?

 

[CROWLER]

What about a prohormone/prosteroid powder you want to take orally. Could this be put into just plain oil and stored for a long time?


CROWLER

 

[DR.D]

Would glycerin then be subbed for peg in the same amounts when used with ethyl alchohol recipes?

It is usually a weaker solvent, just depends, but basically yes. As long as it's not too "wet", it usually works but may take a bit more than PEG. About the same as PG probably. Make sure it's fresh and keep the lid on it very tight. Same for all this stuff really (PEG and ethanol too).

 

[DR.D]

What about a prohormone/prosteroid powder you want to take orally. Could this be put into just plain oil and stored for a long time?


CROWLER

In a suspension you mean? Heck yeah. It lasts forever basically. Add about 1% vitamin E acetate or 0.5% ascorbyl palmitate or BHT and it won't go rancid in the fridge for 10 years probably. Solutions are less stable in oil (~5 years in my experience).

 

[flyingjer]

so what about a glycerin ethyl alcohol polysorbate 80 mix? would that make good solutions for the powders i stated above, in the proper mg/ml strengths that we prefer

 

[DR.D]

so what about a glycerin ethyl alcohol polysorbate 80 mix? would that make good solutions for the powders i stated above, in the proper mg/ml strengths that we prefer

Yeah, it's a good idea. The PS80 would help to make any water content a non-factor. It helps clear up cloudy solutions when too much water is present.

 

[thundergod]

Suspensions give more stable long term storage. As long as your powder says finely dispersed in the medium and will homogenize smoothly when shaken, why not suspend? Solutions are prettier, but for oral apps there is no real advantage usually, plus the active is often decomposed faster. Also important, suspension don't taste as bad!

DR.D--- I know this is an old thread, but I've been asking my question on numerous boards lately, with no clear responses. I have 80 grams of powdered testofen. I have 3 big bottles of extra virgin olive oil. I'm looking to make this more orally bio-available. A guy from primordial performance told me I need to dissolve the testofen first using maybe PGA and some glycerol. I've heard I can get the glycerol at rite-aid under skin protectants. How much PGA and glycerol should I dissolve the 80 grams of testofen into before I add it to the olive oil. And how much olive oil would you suggest putting all of this into? PLEASE HELP!!!