Effect of an Increase in Free Testosterone Brought About by Nettle Root or Activate

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  1. Did you guys ever see this:

    Gansser D, et al. Plant Constituents Interfering with Human Sex Hormone-binding Globulin. Evaluation of a Test Method and Its Application to Urtica dioica Root Extracts. Z Naturforsch.[C]. 1995;50(1-2):98-104.

    Author: Gansser D, Spiteller G
    Date: 1/1995
    Journal: Z Naturforsch

    A test system is described, which allows the search for compounds interfering with human sex hormone-binding globulin (SHBG) even in complex plant extracts. The method has been evaluated and applied to Urtica dioica root extracts. The lignan secoisolariciresinol (5) as well as a mixture of isomeric (11 E)-9,10,13-trihydroxy-11- octadecenoic and (10 E)-9,12,13-trihydroxy-10-octadecenoic acids (3 and 4, resp.) were demonstrated to reduce binding activity of human SHBG. Methylation of the mixture of 3 and 4 increased its activity about 10-fold.
    BV


  2. In laymans terms that would be methylation of the Nettle Root BV??
    My The 1 LOG: http://anabolicminds.com/forum/steroids/254164-my-one-log.html
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  3. Yeah, or at least methylation of some of the constituents in nettle root extract

  4. Quote Originally Posted by BigVrunga
    Yeah, or at least methylation of some of the constituents in nettle root extract
    Wouldn't you have to extract a pure sample or synthesize the active from scratch to methylate it like that? If it translated to real world results that'd be an interesting product to use in and of itself, but once you've got the methylation to deal with why not simply do an AAS cycle though, you know? Unless it was for some reason significantly easier on the liver than existing AAS I wouldn't see the point, at least for using it on cycle. For PCT again it'd be interesting but probably only good for transdermal and injectable cycles. The last thing I'd want to do after an oral cycle is take a methylated PCT supplement.

  5. Not at methylation correlates to toxicity of the liver.
    E-Pharm Rep... PM me with any questions or concerns
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  6. Quote Originally Posted by 3clipseGT
    Not at methylation correlates to toxicity of the liver.
    (at=all) and exactly. Take caffeine for example. Maybe one day, people will understand this.....

  7. good info here bros. thanks doc d for breaking out your knowledge.

  8. Wouldn't you have to extract a pure sample or synthesize the active from scratch to methylate it like that? If it translated to real world results that'd be an interesting product to use in and of itself, but once you've got the methylation to deal with why not simply do an AAS cycle though, you know? Unless it was for some reason significantly easier on the liver than existing AAS I wouldn't see the point, at least for using it on cycle. For PCT again it'd be interesting but probably only good for transdermal and injectable cycles. The last thing I'd want to do after an oral cycle is take a methylated PCT supplement.
    Yeah, you'd have to isolate those compounds via fractional distillation or something similar. Like mentioned above, not all methylated compounds mean undue liver stress. I just thought it was interesting - something like that could mean a serious boost in test levels when combined with an anti-e like ATD. Especially for an older athlete.

    BV

  9. Quote Originally Posted by Max32
    (at=all) and exactly. Take caffeine for example. Maybe one day, people will understand this.....

    Hahaha thanks bro for the spelling correction, got a little ahead of myself!

    Yea caffiene was what i was referring too as well.
    E-Pharm Rep... PM me with any questions or concerns

  10. On another note, Alris ATD is methylated as well, i havnt heard anything but im pretty sure that wouldnt cause liver toxicity either would it?

    I mean on the other hand RXT has been noted to negatively effect lipid profiles as well so whats up with alris methylated ATD?
    E-Pharm Rep... PM me with any questions or concerns
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