Driven by the intent of finding out why I have low T level symptoms although my free testosterone is top range and all my bloods are perfect, I found this article to be a very interesting lead:
Androgen Receptor Sensitivity: All Men Are Not Created Equal | Muscular Development
One's androgen receptor sensitivity seems to be defined by genetics, and more specifically by CAG repeating length.
It has been found that the shorter the CAG (black people) the more masculine and virilizing was the activity of T in contact with the receptors. Asians have long CAG repeating, which explains why they usually have more feminine traits although T levels are similar to the rest of the world.
I'm planning to do a sequencing of my genome to found out my CAG's length, and hopefully explain my symptoms.
1) Does anyone know of any treatment to modulate this length and thus increase androgen receptor sensitivity to T?
2) Does it mean that someone with two times less androgen receptor sensitivity could inject twice as much T and feel the same effects as if he weren't lacking receptor sensitivity?
Androgen Receptor Sensitivity: All Men Are Not Created Equal | Muscular Development
One's androgen receptor sensitivity seems to be defined by genetics, and more specifically by CAG repeating length.
It has been found that the shorter the CAG (black people) the more masculine and virilizing was the activity of T in contact with the receptors. Asians have long CAG repeating, which explains why they usually have more feminine traits although T levels are similar to the rest of the world.
I'm planning to do a sequencing of my genome to found out my CAG's length, and hopefully explain my symptoms.
1) Does anyone know of any treatment to modulate this length and thus increase androgen receptor sensitivity to T?
2) Does it mean that someone with two times less androgen receptor sensitivity could inject twice as much T and feel the same effects as if he weren't lacking receptor sensitivity?