Transdermal vs Oral

[TacTownbeast]

Anyone know how to dose transdermal Stano/ Epiandrosterone? I stack 1200mgs on cycle of oral stano. What would be a good dose transdermally? I am planning on mixing my own, 4 grams in 30ml salvo for 133mg/ml, and running this for 8 weeks as a base for an oral like triumph, halo, or tr3n.

 

[sanmarino]

You should now, that the absorb rate of transdermal product is between 30-60%. Calculate with that, to evaluate a optimal dosage as a oral cycle.
Probably it would be better to invest the money into a very strong liver support as Damage Control than to mix own gel.

 

[RickyBlobby]

You should now, that the absorb rate of transdermal product is between 30-60%. Calculate with that, to evaluate a optimal dosage as a oral cycle.
Probably it would be better to invest the money into a very strong liver support as Damage Control than to mix own gel.

Is oral absorbtion rate considered 100%? With stomach acid and all? Curious....

 

[crgsander]

Is oral absorbtion rate considered 100%? With stomach acid and all? Curious....

No! Absorption rate is higher with trans-dermal.

 

[crgsander]

Anyone know how to dose transdermal Stano/ Epiandrosterone? I stack 1200mgs on cycle of oral stano. What would be a good dose transdermally? I am planning on mixing my own, 4 grams in 30ml salvo for 133mg/ml, and running this for 8 weeks as a base for an oral like triumph, halo, or tr3n.

I have not looked into these. Have you checked that particle size is small enough that the compounds can be used in trans-dermal?

 

[RickyBlobby]

No! Absorption rate is higher with trans-dermal.

I thought so but I read sanmarino's post as he believed oral was 100% and factor that in when using transdermal which is 30-60%

 

[vujade]

Anyone know how to dose transdermal Stano/ Epiandrosterone? I stack 1200mgs on cycle of oral stano. What would be a good dose transdermally? I am planning on mixing my own, 4 grams in 30ml salvo for 133mg/ml, and running this for 8 weeks as a base for an oral like triumph, halo, or tr3n.

how are you getting the fillers out of the Stano/Epiandro...? or were you able to find it in a pure uncut form..?

 

[sanmarino]

No no. You won't get 100% generally, just nearly to 100% (because of the hepatical first-pass-metabolism).
There was a writing paper about bioavaiability between orals, transdermal and inject versions. The transdermal products depends on the additives (like glycerole, benzyl alcohole and this whole stuff).

The result on the study was, that transdermals weren't that much effective (the aim of the study was to evaluate, if transdermals could be an ideal oppurtunity for men and women with a hormonereplacement (like Testogel)).
I have to search that paper...

My thoughts were to use the whole planned PH's as (inject or) oral version with a strong liver care.

 

[RickyBlobby]

No no. You won't get 100% generally, just nearly to 100% (because of the hepatical first-pass-metabolism).
There was a writing paper about bioavaiability between orals, transdermal and inject versions. The transdermal products depends on the additives (like glycerole, benzyl alcohole and this whole stuff).

The result on the study was, that transdermals weren't that much effective (the aim of the study was to evaluate, if transdermals could be an ideal oppurtunity for men and women with a hormonereplacement (like Testogel)).
I have to search that paper...

My thoughts were to use the whole planned PH's as (inject or) oral version with a strong liver care.

Do you still have access to that paper? It seems like the transdermal trest is hitting me harder than the oral, IMO.

 

[crgsander]

No no. You won't get 100% generally, just nearly to 100% (because of the hepatical first-pass-metabolism).
There was a writing paper about bioavaiability between orals, transdermal and inject versions. The transdermal products depends on the additives (like glycerole, benzyl alcohole and this whole stuff).

The result on the study was, that transdermals weren't that much effective (the aim of the study was to evaluate, if transdermals could be an ideal oppurtunity for men and women with a hormonereplacement (like Testogel)).
I have to search that paper...

My thoughts were to use the whole planned PH's as (inject or) oral version with a strong liver care.

Oral is no where even close to 100%! Oral is lower than transdermal!

 

[RickyBlobby]

 

[TacTownbeast]

Yes, the molecular weight is under 300

 

[TacTownbeast]

Stanodrol is not methylated, the reason for dosing so high, but also doesn't pass the liver. If I remember right oral bioavailability is like 5% or so, but also not liver toxic. Your paper seems to go against every thing I've ever seen on orals and topical.

 

[TacTownbeast]

I would be using the raw powder.