greenside
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I discovered this board about a month ago and it is great. This is my first post and I wanted to say hello. That being said, 2 questions:
1) I have seen alot of people using tamoxifen for pct. I was told in a pharmacology class that tamoxifen does not cross the blood brain barrier (BBB) and thus only blocks estrogen action peripherally. If this is the case then it would not reach the pituitary, would not block estrogen there, and would therefore have no effect on LH levels. Does tamoxifen indeed cross the BBB or am I missing something?
2) Assuming tamoxifen does cross the BBB and block estrogen receptors in the pituitary, what about adding some 4ad. I saw someone post they had seen 200% increase in test levels with tamoxifen only. If this is the case why not add low dose 4-ad and elevate your test levels while at the same time blocking it in the pituitary. This would give you normal test levels until your testes responded to the LH and got working again. Am I crazy?
1) I have seen alot of people using tamoxifen for pct. I was told in a pharmacology class that tamoxifen does not cross the blood brain barrier (BBB) and thus only blocks estrogen action peripherally. If this is the case then it would not reach the pituitary, would not block estrogen there, and would therefore have no effect on LH levels. Does tamoxifen indeed cross the BBB or am I missing something?
2) Assuming tamoxifen does cross the BBB and block estrogen receptors in the pituitary, what about adding some 4ad. I saw someone post they had seen 200% increase in test levels with tamoxifen only. If this is the case why not add low dose 4-ad and elevate your test levels while at the same time blocking it in the pituitary. This would give you normal test levels until your testes responded to the LH and got working again. Am I crazy?