If you don't know how "prone" you are to gyno it's a good idea to run it. The trick is to find out what dose is right for you. Unless you're getting constant blood work to keep track of your levels, the only way to figure out what the correct dose is is by "feeling" it out. If you start to notice side effects that are indicative of low estrogen (sore joints, low libido, etc), you'd want to nudge the dose down, and vice-versa. A lot of people fear that they will "limit" their gains but as long as you're not driving your estrogen too low any reduction in "positive" gains wouldn't be a concern in my opinion. Aside from preventing gyno, there are other benefits to controlling estrogen such as reducing bloat and the amount of fat gained on-cycle.
Also, as a note, my opinion about low estrogen and limiting gains is based on what I've seen others report. Those who seem to control estrogen properly while on cycle make just as good gains as those running no estrogen control. Hypothetically, even if you do limit your "positive" gains, weigh that against gaining more fat while on-cycle. Finishing up a cycle with an additional 5+ pounds to cut doesn't sound too appealing to me. The way I look at it, more fat means more time that needs to be invested into cutting, time that could have been spent bulking. This is part of why I don't agree with the "who cares about gaining fat during a bulk?" mindset.