Can pro-steroids assist in wound healing or is it just anavar?
03-19-2009 01:54 AM
Can pro-steroids assist in wound healing or is it just anavar?
Pretty self explanatory title.
I just had surgury today to remove two benign cysts from unerneath the subcutaneous skin of my abdomen. The doctor said in two weeks I could go back to the gym and said that it would take a period of time before the skin surrounding where the cysts were, to tighten back up.
Before the surgury, I was already planning on doing a cycle anyway of:
Epistane - 30 mg a day
Furazadrol - 200 mg a day
11-oxo- 6 caps a day
My question is that I was already planning on using these for a little recomp before summer, but now I'm curious if the use of these anabolics (combined with the cortisol lowering properties of 11-oxo) will accelerate the healing process of my incisions and also with the skin tightening? I have read studies of anavar and even winstrol's effect on skin and wound healing but I didn't know if they just happened to be exceptions.
03-19-2009 09:07 AM
I thought steroids inhibited wound healing,.. I'm no expert though!
Think training's hard,. try losing!
03-19-2009 01:06 PM
Originally Posted by crader
The title is "The Anabolic Steroid, Oxandrolone, Reverses the Wound Healing Impairment in Corticosteroid-Dependent Burn and Wound Patients"
And I know that while cortisol at first has anti-inflammatory actions but later can actually IMPEDE wound healing, so I figured 11-oxo would greatly help in that regard.
But then again I am not sure, so that's why I am glad to get the opinions of the different experts on this forum.
03-20-2009 02:16 AM
03-20-2009 03:48 PM
03-20-2009 08:23 PM
All I know is that cortisol is a major anti-inflammatory, haven't heard of it stopping wounds from healing eventually though? But as far as I know, it is the bodies #1 anti-inflammatory, and to have that reduced would make healing take a lot longer.
03-25-2009 02:55 AM
There are studies that show it slows wound healing. You are right in the beginning it works as an anti-inflammatory, but afterwards high levels of cortisol damage the skin (thats why people with cushing's get stretch marks, it thins the skin).
Originally Posted by wild12
I am just not sure about epistane. Also Furazadrol is similar to winstrol because the steroid it derives from, Furazabol, is similar, but I'm not sure if it differs on the way Winstrol encourages collagen formation.
I could use the advice of someone who knows different roids and their nomenclatures inside and out.
03-25-2009 05:11 PM
to answer your question, maybe, I dont think anyone knows, but for anavar, it's a sure bet, if you have enough money.
03-25-2009 05:21 PM
have fun reading
NOTICE: This information is for entertainment purposes ONLY!
Full profiles on each individual steroid are here.
Pharmaceutical Name: Oxandrolone (OXA)
Chemical Structure: 5 alpha-androstan-2-oxa-17 alpha-methyl-17 beta-ol-3-one
Molecular Weight Of Base: 306.4442
Effective Dose: 20-40 mg/day for men, 10-15 mg/day for women
Average Street-Price: (edited out, but it's alot.) for 10 tabs
Available Doses: 0.5, 2, 2.5, 5mg, 10mg tabs
brands & Products:
Searle Anavar (o.c.) (US) 2.5 mg tabs
Anatrophill (o.c.) (FR) 2.5 mg tabs
Lipidex (Brazil) 2.5 mg tabs
Lonavar (o.c.) (Argentina) 2.5 mg tabs
Dainippon Lonavar (Japan) 2 mg tabs
Societta Prodotti Antibiotica Oxandrolone SPA (I) 2.5 mg tabs
Kowa Vasorome (Japan) 0.5 and 2 mg tabs
Ttokkyo Labs Oxandrolone 5 mg tabs
BioTechnology General (BTG) Oxandrin (US) 2.5 mg tabs
AAn intrinsically weak steroid with a high price-tag and low availability, oxandrolone owes its large popularity due to its safety. In sharp contrast to oxymetholone, oxandrolone is quite generally considered to be the safest of all steroids. Its effects are more than well-documented and have been for a few decades now. The medical community values oxandrolone as a safe alternative for more harmful steroids, which is why it is considered safe for use in children and even in patients suffering hepa-toxicity as the result of alternate steroid use1.
It's most noted medical use has been in the expediting of wound healing2,3 often practically applied to the treatment of burns 4,5,6. But recently its gaining popularity again as a means of keeping weight on HIV-infected patients suffering from wasting due to the immuno-deficiency virus. It was also considered safe for use in prepubescent children with a growth delay7. No major harmful effects were noted from this particular therapy, eventhough one study8 reported that the use of oxandrolone did speed up the onset of puberty in these children. Furthermore oxandrolone has found frequent applications in the treatment of other wasting symptoms for hepatitis and cancer as well as the treatment of osteoporosis in both men and women of all ages.
Oxandrolone was introduced in the year 1964, when Searle came out with the original Anavar. It quickly became the popular drug in the sports crowd for people looking for a safer alternative to the major steroid at the time, Dianabol (methandrostenolone). It remained one of the best-sellers for well over 2 decades until it was indefinitely discontinued in the year 1989. Much to the regret of the recreational bodybuilding and powerlifting community. The prices have remained high for the little stock that remained available. The only brand readily found was oxandrolone SPA, manufactured in Milano, Italy. That is, until 1995 when its use in the treatment of the then vastly spreading immuno-deficiency disease AIDS9 sparked the interest of BTG, a US-based company who came out with Oxandrin. The first widely available oxandrolone product since Anavar production was stopped.
The main reasons for the wide-spread use of oxandrolone in sports is because it is very appealing to female athletes as well as male athletes. It causes little or no virilization properties, demonstrated by its medical uses to treat women. This is rather surprising since oxandrolone does not aromatize either. It's the only steroid that is both safe and convenient without producing excess estrogen. That makes it particularly useful when cutting up for a contest or preventing an increase in body-fat due to estrogenic effects. In fact the main use of oxandrolone to a bodybuilder is in the maintenance of lean mass while reducing body-fat. Oxandrolone itself may not actually reduce body-fat, but it too plays a key role in the process. Like most non-aromatizing compounds it has a repressing effect on the appetite making it easier for the user to control cravings and stay strict with his diet.
Oxandrolone also has little effect on the body's own natural hormone production. The negative feedback was found to be very minor, meaning that during short term use no suppression of Gonadotropin releasing hormone (GnRH, start of natural testosterone production) was noted. This meant that whatever gains made, as little as they may have been, were very easily maintained post-cycle. So there was also no use for products like Clomid or Nolvadex in conjunction with oxandrolone consumption. The easy to maintain low gains would indicate a low binding to the androgen receptor. While not extremely high, it should actually be noted that it does have quite decent binding to the androgen receptor. But the reason for its mild effects is quite likely the low dose used. Rarely if ever are doses higher than 20 mg used on a daily basis. Either because of convenience or due to the high price. But comparing that the doses of other steroids this is remarkably low. So its only logical the gains and side-effects aren't particularly notable.
Of course a bodybuilder has limited use for a compound that is both a weak androgen in the doses mostly used and doesn't aromatize since no mentionable effect on mass can be produced to satisfy the chemically enhanced athlete. Therefor it is best noted that oxandrolone is most popular with power- and weightlifters to enhance strength without increasing bodyweight. This is valued highly since strength athletes often compete in weight-classes. Oxandrolone does not increase strength through androgenic stimulation, at least not primarily. It stimulates the formation of phosphocreatine, a body compound that can replenish ATP (adenosine tri-phosphate) , the main energy currency of the living organism. This gives an incredible increase in short term anaerobic performance, the type needed for explosive action such as sprinting and lifting weight.
For bodybuilders the best results are seen when stacking oxandrolone with a highly androgenic compound. Either during a mass stack with aromatizable products to boost strength a little more, or in conjunction with a non-estrogenic compound. This is most beneficial since it can maintain lean mass, decrease appetite, improve sharpness of the muscle and keep strength levels up without giving increased androgenic risk (acne, prostate hypertrophy, hair loss) when stacked with pure androgens (stanozolol, drostanolone). For those looking for safe maintenance of muscle mass a stack of Anavar with Primobolan is not a bad investment (but a big investment). The common use of oxandrolone is estimated, at 0.125 mg per pound of bodyweight. For men it should be closer to 0.2 mg per pound, for women 0.08 mg per pound per day.
The downsides to oxandrolone are minor. The worst problem by far is the poor availability and high price. But it has to be noted that, eventhough oxandrolone is nowhere near Halotestin or anadrol in hepa-toxicity, it too is a 17-alpha-alkylated substance that can cause liver damage if used for long periods on end. Other common side-effects include headaches, loss of libido, diarrhea and dizziness.
The conclusion to follow these paragraphs is of course that oxandrolone is understandably still a popular and very versatile steroid, much desired by both experienced athletes and novice users because of its many properties. While few will say this is the best or their favorite steroid, you won't find many that will have anything negative to say about it either.
Stacking and Use:
Because of its mild nature and the low doses generally used with oxandrolone there is very little use for secondary compounds like anti-aromatase drugs, estrogen receptor antagonists or blood pressure medication. That in itself may somewhat make up for the high cost and little gains made on it.
In stacks Anavar is sometimes used to increase strength or help maintain it during mass phases. Oxandrolone obviously has very little to add in terms of mass compared to the other substances used to obtain such goals. It fades in comparison to test, Deca, Anadrol, D-bol and such. Nonetheless it is added quite often, perhaps because people assume it will make the overall stack less hazardous, but that's a myth of course. Frankly I would imagine there are better and cheaper things to waste your money on if mass is what you seek.
On a cutting phase oxandrolone makes a good match for 120-140 mcg of clenbuterol daily stacked with something in the nature of Halotestin or Winstrol. The combination improves muscle hardness and striation as well as support mass and strength retention. Experienced users would preferably add testosterone propionate or Equipoise no doubt, rather than Halotestin or Winstrol due to less hazard to the liver associated with those two drugs, especially Halotestin.
Mostly it is used for decent strength gains without gaining too much weight, particularly suited for weight- and powerlifters and martial artists. In that aspect, and in my humble opinion, Winstrol would be a good choice for a stack. 50 mg of Winstrol every day to every other day stacked with 30-40 mg of oxandrolone daily would give a very good result in overall strength enhancement without adding a mentionable amount of weight to the frame.
1 Segal S, Cooper J, Bolognia J., Treatment of lipodermatosclerosis with oxandrolone in a patient with stanozolol-induced hepatotoxicity., J Am Acad Dermatol 2000 Sep;43(3):558-9
2 Demling RH., Oxandrolone, an anabolic steroid, enhances the healing of a cutaneous wound in the rat., Wound Repair Regen 2000 Mar-Apr;8(2):97-102
3 Demling RH, Orgill DP., The anticatabolic and wound healing effects of the testosterone analog oxandrolone after severe burn injury., J Crit Care 2000 Mar;15(1):12-7
4 Hart DW, Wolf SE, Ramzy PI, Chinkes DL, Beauford RB, Ferrando AA, Wolfe RR, Herndon DN., Anabolic effects of oxandrolone after severe burn., Ann Surg 2001 Apr;233(4):556-64
5 Demling RH, DeSanti L., The rate of restoration of body weight after burn injury, using the anabolic agent oxandrolone, is not age dependent., Burns 2001 Feb;27(1):46-51
6 Demling RH, DeSanti L., Oxandrolone, an anabolic steroid, significantly increases the rate of weight gain in the recovery phase after major burns., J Trauma 1997 Jul;43(1):47-51
7 Papadimitriou A, Preece MA, Rolland-Cachera MF, Stanhope R., The anabolic steroid oxandrolone increases muscle mass in prepubertal boys with constitutional delay of growth., J Pediatr Endocrinol Metab 2001 Jun;14(6):725-7
8 Doeker B, Muller-Michaels J, Andler W, Induction of early puberty in a boy after treatment with oxandrolone? Horm Res 1998;50(1):46-8
9 James JS., Wasting syndrome: oral oxandrolone re-released in U.S., AIDS Treat News 1995 Dec 22;(no 237):3-4
03-26-2009 04:22 PM
Thanks man! I guess I'll just give the cycle a run and see what happens.
Originally Posted by jbryand101b
03-26-2009 11:07 PM
I've never tried it, but topical insulin has been used to speed the healing process.
03-27-2009 04:52 PM
Wow that's an interesting read!
Originally Posted by dingling
03-30-2009 10:17 PM
Keep us updated on what you decide and how it works out.
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