- 11-26-2003, 12:36 PM
I don't know a whole lot about chemistry so this might be a stupid idea, but it sounds interesting to me. With all the methyl-ph's out now and new ones coming, how about methylating 6-oxo or formestane for a super anti-estrogen? Or maybe 7-keto or it's derivitives. Could create a super potent compound??? Does anybody know what these compounds would do or if they exist?
- 11-26-2003, 03:17 PM
- 11-26-2003, 03:33 PM
i dont think methyling a product would necessarily make them stronger....but more bioavilable for sure.
11-26-2003, 05:16 PM
yeah it's not gonna make them strong anti-es
it just makes them more bio-available so they wont' get broken down into being useless.
11-26-2003, 05:52 PM
11-27-2003, 12:55 AM
exactly. therefore its kinda pointless.. especially when things ilke nolva and such are so cheap..Originally posted by mass_builder
also more liver toxic
11-28-2003, 09:39 AM
Remember, these compounds have to fit inside a receptor and any substituent addition will affect its ability to bind.
As was posted above, with the availability of liquid research products there is no need for methylated 6-oxo.
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