Basically the cause of acne is a defect or deficiency in a person's metabolism of lipids (fats) which occurs due to a lack of coenzyme-A in the body. Coenzyme-A is made of ATP (energy), cysteine, and pantothenic acid. Of these 3, pantothenic acid is the only one which is a vitamin and must be supplied through the diet. The other 2 are produced by the body. So if you supplement with pantothenic acid you create more Coenzyme-A in your body and your fats get metabolized. A lack of Coenzyme-A in the body means that fats don't get broken down. Instead, they get deposited in your sebaceous (oil) glands and get secreted as sebum (oil). Oil is a fat in liquid form. You get acne because the acne bacteria (Propionibacterium acne) in your pores feeds on this excess oil