I'm skeptical like many others are about the effectiveness of methyl 4-AD. I also don't see the point of using methyl 4-AD in a transdermal, when you could get near 100% bioavailability orally. At this point I haven't seen anyone report on it's effectiveness and anyone that has supposedly used it with success has not posted their results. IMO stick with a standard 4-AD transdermal like T-4. I would also use Nolva for post cycle. If you feel like experimenting than by all means give it a try.