Andromass a no-no with a statin?
- 04-08-2011, 08:12 PM
- 04-08-2011, 08:18 PM
04-08-2011, 09:19 PM
No you cannot take a statin with AM.
The Interaction Between Grapefruit and Statins
Grapefruit contains the compound bergamottin, which interacts with certain enzyme systems in the body, such as cytochrome P-450 and P-glycoprotein. These enzyme systems are responsible for breaking down statins, as well as other drugs, into more usable chemicals and transporting them in the body.
When grapefruit juice is consumed at or around the time you take your statin, the components in grapefruit prevent these enzyme systems from breaking down the drug, causing the drug to accumulate in high amounts in the body. This can be very dangerous and can cause a variety of health problems, such as liver damage or a rare condition called rhabdomyolysis (severe muscle and kidney damage).
Are All Statins Affected?
So far, the only statins significantly affected by this interaction are:
Other statins do not seem to demonstrate the same, profound effect with grapefruit as seen with the other statins. These would include:
pravastatin (Pravachol ®)
fluvastatin (Lescol ®)
pitavastatin (Livalo ®)
Some scientists think that this may be due to the fact that these statins are not broken down by the same enzymes.
04-08-2011, 09:27 PM
04-09-2011, 12:52 AM
04-09-2011, 04:51 PM
04-09-2011, 05:04 PM
04-09-2011, 05:18 PM
04-09-2011, 05:27 PM
i think my pharm notes states a 4x increase in risk for CAD with lipids over 250
anyways, doctor prescribed it for a certain reason. you should follow you doctors protocol
04-09-2011, 07:03 PM
04-09-2011, 07:54 PM
Source is my internal medicine class and my anesthesia professor who works cardiovascular compromised patients. I can't post notes due to copy right issues. Also covered in my pharmacology classes
If ur that interested I can pm u the books we use
04-09-2011, 08:03 PM
Statins canloer ldl by as much as 60% and r some of the most efficacious hypolipidemic agents available
04-10-2011, 10:22 AM
There's nothing I can say to sway you from thinking statins are a good idea or that total cholesterol is a valid predictor of future CV events. To me, it would be in his bets interest to fix his diet (high fat, high protein, low carb) than to spend his money on a drug that has not been shown to lower the rate of CVD. Like I said, though, there's not a lot of money to be made by either doctors or pharmaceutical companies if people were given good information regarding nutrition and exercise.
M.Ed. Ex Phys
04-10-2011, 11:42 AM
The Historic PES Legend
04-10-2011, 12:56 PM
your response is simple and complex at the same time. Yes lifestyle changes would be beneficial and may deter medications but compliance is the main issue. For instance, I just walked by the hospital 10 min ago, what did I see? A patient hooked up to a IV drip smoking a cig. I can guarantee you 100% that she was advised not to smoke. Did she listen, hell no. If you spend any amount of time in a clinic, you would understand this issue. We do advise lifestyle changes during appointment. A lot of times, patients can't afford treatment, so we offer what advice we can.
sometimes your daily activities make it complicated for you to make lifestyle changes. I go to school 8 hours a day, do lab work after, go to the library after, by the time I get home, it's about midnight or later. I know the importance of exercise and diet. Do I practice it, not really cause I'm so dam busy. My blood pressure is rising cause of stress. Non-drug therapy would be to eliminate stress. Can I eliminate it, hell no. I'm surrounded it.
Noncompliance is even riddled thru-out bodybuilding forums, even though forums consists of a skewed population. If this is a skewed population, how do you think the mean population will perform. And to take it even further, what about the people at the opposite end of the spectrum.
Not all doctors all are greedy pocket pinchers. You're not looking at the whole story.
One could probably think the same way about supplement companies. Why not just adjust diet and exercise to lose that extra 1-2% of body fat instead of using fat loss supplements. Why don't reps advise not to use their supps, instead focus more on tweaking diet and exercise and use that money towards buying a proper meal.
04-10-2011, 01:38 PM
I hate the "pill for every ill" position of the American medical community. Restore balance to the body and it will correct itself, but, as I said, that's not a very profitable endeavor. It really doesn't help that the diets advocated by doctors and the USDA are high carb, which often leads to insulin resistance and hyperlipidmeia.
M.Ed. Ex Phys
04-10-2011, 01:43 PM
Some people are just in love with western medicine and don't bother reading and researching and asking questions. Don't stress bro, just let him worry about his cholesterol and take drugs that will leave him worse off.
I used to get upset. But now I don't worry so much. You'll just die (not you Rodja) and I'm fine with that.
04-10-2011, 01:50 PM
But yet the lowering of cholesterol reduces the rate of CVD. If you just have nothing to back you up, say so, it is your opinion, otherwise don't start off as a jack ass when I ask you a question and provide a meta analysis to back up my position.Not to mention that there isn't strong evidence linking high cholesterol to CVD.
Then you say:
Which I posted the antithesis to. Yet get a smart ass remark instead of clarification.To me, it would be in his bets interest to fix his diet (high fat, high protein, low carb) than to spend his money on a drug that has not been shown to lower the rate of CVD.
The Historic PES Legend
04-10-2011, 02:04 PM
Funny you post that since there is not mention of any dietary interventions, which will not only be cheaper, but also is just as efficacious and has no side effects. Instead of attacking just the hypercholestemia, you can attack the other dangers such as Metabolic Syndrome. Again, quit being a shill of the drug companies and learn how to eat properly. you'll not only extend your life, but increase the quality of your life.
M.Ed. Ex Phys
04-10-2011, 02:05 PM
so where's your medical degree. if it was that simple, we wouldn't have multiple specialities.
ever heard of adjuncitve therapy.
body can't correct itself of every disease. your theory has limits.
i think you'll find it very difficult to get a patient with CHF to exercise. You could try, but he'll probably end of dying before you make any progress.
can't imagine advocating proper diet and exercise being profitable for supps companies either.
seems like the thread is turning for the worse. I didn't come to start a debate.
how bout we return to op's concerns.
04-10-2011, 03:43 PM
When you can provide something to back up your stance, you go ahead and come back. Funny I was actually just looking for incite, instead I get your attitude.
The Historic PES Legend
04-11-2011, 12:36 AM
04-11-2011, 03:29 PM
I eat well.....well enough to have abs and 9% body fat. Lift 5 days a week on a split routine and run or bike for many miles a week. Guess what......my LDL will not go below 130! It's easy to sit back and say diet and exercise can fix all our woes, but I am living proof that it cannot always fix cholesterol. I won't get into the argument of weather the cholesterol myth is real or not. My doc wants me on some type of med, so far I have resisted, but wont I feel the fool if I fall over with a heart attack!
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