Product request

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    Product request


    Could you guys make an estrogen blocker/metaboliser, specifically estradiol e2?

    There are some people out there on HRT/TRT who use arimidex, but also a lot of ppl who have high levels of this and are taking DIM, zinc, chrysin etc.. as a natural means to combat this.

    Perhaps you know some good compounds with your high availability technology which can combat this?

    I am thinking not stuff like ATD or other compounds which harm libido, lipids etc..

    Please come up with something, i believe there is a big market!

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    Have you tried Sustain Alpha? I have used it many times and it always worked like magic for my PCT protocols and raised my libido big time, not sure though for use while on HRT/TRT, I will look into it and get back to you.
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    Here is an article about resveratrol and libido, hope this helps.


    Resveratrol better than Viagra?
    Eric Potratz

    Resveratrol Better Than Viagra

    October 14th, 2009 Drugs like Viagra (Sildenafil citrate) and Cialis (Tadalafil) are used to treat erectile dysfunction (ED) by increasing blood flow to the erectile tissue in the penis known as the corpus cavernosum.

    These drugs increase blood flow to erectile tissue by inhibiting the phosphodiesterase enzymes (PDE5 & 6), which prolongs the action of cGMP in the smooth muscle tissue, increasing the dilation response from nitric oxide (NO) release. However, inhibition of the phosphodiesterase enzyme system has effects across the entire body and can lead to side-effects including headache, skin flushing, nasal congestion and muscle aches. (1) These are very unwelcome side-effects when trying to stimulate sexual arousal.

    New research suggests that resveratrol can also trigger erections by promoting blood flow to the erectile tissue in the penis. (2) This vasodilatory effect appears to occur within minutes of resveratrol exposure, suggesting that supplementation may provide a quick temporary boost in sexual performance. (3)

    Evidence suggests that resveratrol does not have the side-effects typically associated with popular ED drugs. Resveratrol improves vasodilation by multiple cellular mechanisms, and does not negatively inhibit the phosphodiesterase enzyme system, which can lead to unwanted side-effects. (3) Whether or not resveratrol is a worthy substitute to powerful prescription drugs such as Viagra and Cialis remains to be determined.


    -Eric Potratz
    Founder & President


    References

    1. [Sildenafil (Viagra) in erectile dysfunction. Effective treatment with noteworthy side effects]
    C Rolf and E Nieschlag
    Dtsch Med Wochenschr, Nov 1998; 123(45): 1356-61.

    2. trans-Resveratrol relaxes the corpus cavernosum ex vivo and enhances testosterone levels and sperm quality in vivo.
    Shin S, Jeon JH, Park D, Jang MJ, Choi JH, Choi BH, Joo SS, Nahm SS, Kim JC, Kim YB.
    Arch Pharm Res. 2008 Jan;31(1):83-7.

    2. Resveratrol, a component of red wine, elicits dilation of isolated porcine retinal arterioles: role of nitric oxide and potassium channels.
    Nagaoka T, Hein TW, Yoshida A, Kuo L.
    Invest Ophthalmol Vis Sci. 2007 Sep;48(9):4232-9.
    •   
       

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    Quote Originally Posted by HATEFULone View Post
    Have you tried Sustain Alpha? I have used it many times and it always worked like magic for my PCT protocols and raised my libido big time, not sure though for use while on HRT/TRT, I will look into it and get back to you.
    hey man thx for the reply

    i didn't try it, but i have such high e levels that some of the moderators in the past told me it wouldn't get it down

    48 on scale to 53 or something like that, now on TRT i am getting even higher

    i am getting arimidex next week from pharmacy so we'll see how that works, i had been on it in the past from ADC but it gave me bad reactions, i am now getting film coated tabs from my pharmacy so hopefully this will be the good stuff
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    If it is related to a medical issue, which in this case it sounds like it is, it is best to see a physician, an endocrinologist would be best. Before starting anything supplement wise I would get blood work and talk to your physician about all supplements you are and have taken, don't be afraid of bringing up any past AAS use, if you have used that is, most of them are cool about it. Hope this helps.
  

  
 

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