SERM`s

  1. Elite Member
    MAxximal's Avatar
    Stats
    5'11"  235 lbs.
    Join Date
    Jan 2009
    Age
    37
    Posts
    6,901
    Rep Power
    122082
    Level
    55
    Lv. Percent
    25.35%
    Achievements Activity ProPosting ProPosting Authority

    SERM`s


    Hello

    The Serms works on Receptors?
    i`m little confused about that (more estrogen= need more receptors to attach to)..


    thanks
    SNS Online Representative
    Maxximal @ seriousnutritionsolutions.com

    Got Glycophase ...?



  2. crazyfool405's Avatar
    Stats
    5'10"  198 lbs.
    Join Date
    May 2008
    Posts
    7,430
    Rep Power
    0
    Level
    55
    Lv. Percent
    20.55%
    Achievements Activity ProPosting ProPosting Authority

    im a little confused on your question

    ERa and ERb are 2 receptor types, ERa in the breast, and some other tissues, ERb in the bones.

    it Antagonizes ERa (blocking binding of estrogen to the ER)
    Agonizes ERb (causing more favorable lipids, and bone density)

    help a little?
  3. Elite Member
    MAxximal's Avatar
    Stats
    5'11"  235 lbs.
    Join Date
    Jan 2009
    Age
    37
    Posts
    6,901
    Rep Power
    122082
    Level
    55
    Lv. Percent
    25.35%
    Achievements Activity ProPosting ProPosting Authority

    Quote Originally Posted by crazyfool405 View Post
    im a little confused on your question

    ERa and ERb are 2 receptor types, ERa in the breast, and some other tissues, ERb in the bones.

    it Antagonizes ERa (blocking binding of estrogen to the ER)
    Agonizes ERb (causing more favorable lipids, and bone density)

    help a little?
    cool man!

    and some serms cause estrogen rebound or not?
    SNS Online Representative
    Maxximal @ seriousnutritionsolutions.com

    Got Glycophase ...?


    •   
       

  4. crazyfool405's Avatar
    Stats
    5'10"  198 lbs.
    Join Date
    May 2008
    Posts
    7,430
    Rep Power
    0
    Level
    55
    Lv. Percent
    20.55%
    Achievements Activity ProPosting ProPosting Authority

    Quote Originally Posted by MAxximal View Post
    cool man!

    and some serms cause estrogen rebound or not?
    no is excessive estrogen post cycle that causes that IMO. SERMs dont help with the Circulating estrogen, so if its high when on them, itll be high when off them, so a low dose Steroidal AI week 2-4 (aromasin 10mg) and then continuing the serm to week 5 should cause no rebound. Actually the only thing that helped keep my gyno away.
  5. Elite Member
    MAxximal's Avatar
    Stats
    5'11"  235 lbs.
    Join Date
    Jan 2009
    Age
    37
    Posts
    6,901
    Rep Power
    122082
    Level
    55
    Lv. Percent
    25.35%
    Achievements Activity ProPosting ProPosting Authority

    Quote Originally Posted by crazyfool405 View Post
    no is excessive estrogen post cycle that causes that IMO. SERMs dont help with the Circulating estrogen, so if its high when on them, itll be high when off them, so a low dose Steroidal AI week 2-4 (aromasin 10mg) and then continuing the serm to week 5 should cause no rebound. Actually the only thing that helped keep my gyno away.
    I got a bottle of transdermal 6-oxo maybe not works?
    SNS Online Representative
    Maxximal @ seriousnutritionsolutions.com

    Got Glycophase ...?


  6. crazyfool405's Avatar
    Stats
    5'10"  198 lbs.
    Join Date
    May 2008
    Posts
    7,430
    Rep Power
    0
    Level
    55
    Lv. Percent
    20.55%
    Achievements Activity ProPosting ProPosting Authority

    Quote Originally Posted by MAxximal View Post
    I got a bottle of transdermal 6-oxo maybe not works?
    Nah only bc it DOES NOT lower E2.. it you wanna go from ADEX to 6oxo then ok
  7. Elite Member
    MAxximal's Avatar
    Stats
    5'11"  235 lbs.
    Join Date
    Jan 2009
    Age
    37
    Posts
    6,901
    Rep Power
    122082
    Level
    55
    Lv. Percent
    25.35%
    Achievements Activity ProPosting ProPosting Authority

    i found this:

    Non steroidal AI's can cause rebound and poss suppression. If you choose an AI go for a steroidal like ATD or 6-OXO.
    SNS Online Representative
    Maxximal @ seriousnutritionsolutions.com

    Got Glycophase ...?


  8. crazyfool405's Avatar
    Stats
    5'10"  198 lbs.
    Join Date
    May 2008
    Posts
    7,430
    Rep Power
    0
    Level
    55
    Lv. Percent
    20.55%
    Achievements Activity ProPosting ProPosting Authority

    Quote Originally Posted by MAxximal View Post
    i found this:

    Non steroidal AI's can cause rebound and poss suppression. If you choose an AI go for a steroidal like ATD or 6-OXO.
    doesnt matter in your case bc you are going to a steroidal after the non steroidal.
  

  
 

Similar Forum Threads

  1. Havoc stack, to SERM or not to SERM.
    By ChaoticReign in forum Post Cycle Therapy
    Replies: 15
    Last Post: 08-07-2009, 04:31 AM
  2. just one week of SERM? short term serm
    By elabor in forum Post Cycle Therapy
    Replies: 5
    Last Post: 04-20-2009, 01:14 AM
  3. SERM or Non-SERM for Hdrol?
    By jnoodles in forum Post Cycle Therapy
    Replies: 13
    Last Post: 05-10-2008, 01:30 PM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Log in
Log in