SERM`s

  1. SERM`s


    Hello

    The Serms works on Receptors?
    i`m little confused about that (more estrogen= need more receptors to attach to)..


    thanks
    SNS Online Representative
    Maxximal @ seriousnutritionsolutions.com

    Got Glycophase ...?




  2. im a little confused on your question

    ERa and ERb are 2 receptor types, ERa in the breast, and some other tissues, ERb in the bones.

    it Antagonizes ERa (blocking binding of estrogen to the ER)
    Agonizes ERb (causing more favorable lipids, and bone density)

    help a little?

  3. Quote Originally Posted by crazyfool405 View Post
    im a little confused on your question

    ERa and ERb are 2 receptor types, ERa in the breast, and some other tissues, ERb in the bones.

    it Antagonizes ERa (blocking binding of estrogen to the ER)
    Agonizes ERb (causing more favorable lipids, and bone density)

    help a little?
    cool man!

    and some serms cause estrogen rebound or not?
    SNS Online Representative
    Maxximal @ seriousnutritionsolutions.com

    Got Glycophase ...?


    •   
       


  4. Quote Originally Posted by MAxximal View Post
    cool man!

    and some serms cause estrogen rebound or not?
    no is excessive estrogen post cycle that causes that IMO. SERMs dont help with the Circulating estrogen, so if its high when on them, itll be high when off them, so a low dose Steroidal AI week 2-4 (aromasin 10mg) and then continuing the serm to week 5 should cause no rebound. Actually the only thing that helped keep my gyno away.

  5. Quote Originally Posted by crazyfool405 View Post
    no is excessive estrogen post cycle that causes that IMO. SERMs dont help with the Circulating estrogen, so if its high when on them, itll be high when off them, so a low dose Steroidal AI week 2-4 (aromasin 10mg) and then continuing the serm to week 5 should cause no rebound. Actually the only thing that helped keep my gyno away.
    I got a bottle of transdermal 6-oxo maybe not works?
    SNS Online Representative
    Maxximal @ seriousnutritionsolutions.com

    Got Glycophase ...?



  6. Quote Originally Posted by MAxximal View Post
    I got a bottle of transdermal 6-oxo maybe not works?
    Nah only bc it DOES NOT lower E2.. it you wanna go from ADEX to 6oxo then ok

  7. i found this:

    Non steroidal AI's can cause rebound and poss suppression. If you choose an AI go for a steroidal like ATD or 6-OXO.
    SNS Online Representative
    Maxximal @ seriousnutritionsolutions.com

    Got Glycophase ...?



  8. Quote Originally Posted by MAxximal View Post
    i found this:

    Non steroidal AI's can cause rebound and poss suppression. If you choose an AI go for a steroidal like ATD or 6-OXO.
    doesnt matter in your case bc you are going to a steroidal after the non steroidal.
  

  
 

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