For compounds that does not aromatize like epi, why some people use an AI for PCT?
Isn't useless when there's no estrogen when you come off cycle?
Enlighten me!
Isn't useless when there's no estrogen when you come off cycle?
Enlighten me!
there is no guarantee there will be no estrogenIf there's no estrogen coming off cycle, how would the AI control the estrogen?
correct me guys.
if theres no estrogen when you come off, chances are there no test either.
As the test comes back, aromatizing occurs and you are left with above normal estrogen levels floating around while you reach normal levels. Using an AI/SERM blocks receptors and kills the enzyme.
From Understanding Post Cycle T Recovery
by William Llewellyn
The Role of Anti-estrogens
It is important to understand that anti-estrogens alone do not do much to restore endogenous testosterone release after a cycle. Normally they only foster LH by blocking the negative feedback of estrogens, and we now see that LH rebounds quickly without help anyway. Plus, post cycle there is not an elevated level of estrogen for anti-estrogens to block, as testosterone (now suppressed) is a major substrate used for the synthesis of estrogens in men. Serum estrogen levels will actually be lower here as a result, not higher. Any estrogen rebound that occurs post-cycle likewise happens concurrently with a rebound in testosterone levels, not prior to it (note there is an imbalance in the ratio post cycle, but this is another topic altogether). We are seeing no mechanism in which anti-estrogenic drugs can really help here. We can see why this fact would not be difficult to overlook, however. The medical literature is filled with references showing anti-estrogenic drugs like Clomid and Nolvadex to increase LH and testosterone levels, and in normal situations these drugs do indeed increase endogenous androgen production by blocking the negative feedback of estrogens. Combine this with the fact that just as many studies can be found to show that steroid use lowers LH levels when suppressing testosterone, and we can see how easy it would be to jump to the conclusion that post-cycle we need to focus on restoring LH. We would miss the true problem of testicular desensitization unless we were really looking into the actual recovery rates of the hormones involved. When we do, we immediately see little value in using anti-estrogenic drugs.
Great stuff.From Understanding Post Cycle T Recovery
by William Llewellyn
The Role of Anti-estrogens
It is important to understand that anti-estrogens alone do not do much to restore endogenous testosterone release after a cycle. Normally they only foster LH by blocking the negative feedback of estrogens, and we now see that LH rebounds quickly without help anyway. Plus, post cycle there is not an elevated level of estrogen for anti-estrogens to block, as testosterone (now suppressed) is a major substrate used for the synthesis of estrogens in men. Serum estrogen levels will actually be lower here as a result, not higher. Any estrogen rebound that occurs post-cycle likewise happens concurrently with a rebound in testosterone levels, not prior to it (note there is an imbalance in the ratio post cycle, but this is another topic altogether). We are seeing no mechanism in which anti-estrogenic drugs can really help here. We can see why this fact would not be difficult to overlook, however. The medical literature is filled with references showing anti-estrogenic drugs like Clomid and Nolvadex to increase LH and testosterone levels, and in normal situations these drugs do indeed increase endogenous androgen production by blocking the negative feedback of estrogens. Combine this with the fact that just as many studies can be found to show that steroid use lowers LH levels when suppressing testosterone, and we can see how easy it would be to jump to the conclusion that post-cycle we need to focus on restoring LH. We would miss the true problem of testicular desensitization unless we were really looking into the actual recovery rates of the hormones involved. When we do, we immediately see little value in using anti-estrogenic drugs.
That's not how it works. It is an anabolic oral steroid which also happens to block aromatase. It's main effects are through it's anabolic actions. It will surpress your natural test. In the beginning of a cycle it may give you a boost though which is why many people report an initial boost in libido.So if it works by decreasing estrogen thereby creating an anabolic state (greater ratio between e and test -test being produced naturally by the body)i am not clear either why pct is required. Theres no pct for 6-oxo . nolvedex xt so its not clear to me either why pct is necessary