The beautiful design of the human body:
"In human males, the urethra passes right through the prostate gland, a gland very prone to infection and subsequent enlargement. This blocks the urethra and is a very common medical problem in males. Putting a collapsible tube through an organ that is very likely to expand and block flow in this tube is not good design. Any moron with half a brain (or less) could design male "plumbing" better."
"Wisdom teeth. Our jaws are a bit small for these late-erupting teeth; some people have them, while others do not."
Why?
"Speaking of the human body, 70% of us suffer lower back pain, since our vertebrae are better designed to function as horizontal suspension bridges for our internal organs rather than as vertical supports for a bipedal mammal.
"Other marvels of human body design include flat feet, weak ankles and knees, varicose veins, heart failure, dangerously thin portions of the skull, teeth that are impacted (or crooked and badly crowded), hernias, hemorrhoids, allergic reactions, eye problems, appendicitis, gall bladder disease, prostate problems, "female problems," danger of choking (because our breathing passage, eating passage, and speech box are all right on top of each other), not to mention countless birth defects"
Regarding the appendix
"The human appendix is notorious for the life-threatening complications it can cause. Deadly infection of the appendix at a young age is common, and the lifetime risk of acute appendicitis is 7% (Addiss et al. 1990; Hardin 1999; Korner et al. 1997; Pieper and Kager 1982). The most common age for acute appendicitis is in prepubescent children, between 8 and 13 years of age. Before modern 20th-century surgical techniques were available, a case of acute appendicitis was usually fatal. Even today, appendicitis fatalities are significant (Blomqvist et al. 2001; Luckmann 1989).
The small entrance to this dead-end pocket makes the appendix difficult to clean out and prone to physical blockage, which ultimately is the cause of appendicitis (Liu and McFadden 1997). This peculiar structural layout is quite beneficial for a larger cellulose-fermenting caecum, but it is unclear why gut lymphoid tissue would need to be housed in a remote, dead-end tube with negligible surface area. In fact, 60% of appendicitis cases are due to lymphoid hyperplasia leading to occlusion of the interior of the appendix, indicating that the appendix is unusually prone to abnormal proliferation of its lymphoid tissue (Liu and McFadden 1997). Such an occurrence would be much less problematic if the interior of the appendix were not so small, confined, and inaccessible from the rest of the gut. In many other primates and mammals, the GALT lymphoid tissue appears to function without difficulty in a much more open, bulbous caecum with ample surface area.
Furthermore, there is mounting evidence that removing the appendix helps prevent ulcerative colitis, a nasty inflammatory disease of the colon (Andersson et al. 2001; Buergel et al. 2002; Judge and Lichtenstein 2001; Koutroubakis and Vlachonikolis 2000; Koutroubakis et al. 2002; Naganuma 2001; Rutgeerts 1994). This evidence suggests that the appendix is actually maladaptive, and that the lymphoid tissue contained in the appendix is prone to chronic pathological inflammatory states. If the appendix does have an important function that we have yet to find, it is a leading candidate for the worst designed organ in the human body. How nice if the appendix would just degenerate away after it is no longer needed, so it could never get infected and kill us needlessly. Any biological structure that supposedly ensures our livelihood by its functions, yet paradoxically and unnecessarily kills a large fraction of its bearers prematurely, is poorly designed indeed."