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New Erase Pro

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    New Erase Pro


    The formula is now posted to the PES website, currently without any detail/explanation.
    The new ingredients are new to me, anyone have thoughts on this new formula? I'm anxious for the Cooper explanation to drop.

    http://pescience.com/erase-pro.html

    The new formula ingredients:

    Boerhaavia diffusa extract - A dual phase modulator


    Uncaria tomentosa extract - Engineered extract


    DHAA (Abieta-8,11,13-trien-18-oic acid) - High affinity AI and more...
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    I will get to it this weekend, gotta focus on school for a bit . But tell ya what...do some research on the compounds (obviously the latter two) and post it up here. Let's see how many pieces of the puzzle the forum can put together prior to the full research presentation
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    I will rep all relevant studies
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    So are you guys going to do to Cat's Claw what you did to AC?
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    It is compound 4 in this excerpt

    Planta Med., 2009 vol. 75(4) pp. 351-5 Isolation and biological activities of neomyrrhaol and other terpenes from the resin of Commiphora myrrha Su, SL; Duan, JA; Tang, YP; Zhang, X; Yu, L; Jiang, FR; Zhou, W; Luo, D; Ding, AW

    A new cycloartane-type triterpene named cycloartane-1alpha,2alpha,3beta,25-tetraol (neomyrrhaol) (1), along with four known terpenes, sandaracopimaric acid (2), abietic acid (3), 2-methoxy-5-acetoxyfruranogermacr-1(10)-en-6-one (4), and dehydroabietic acid (5) have been isolated from the resin of COMMIPHORA MYRRHA. Their structures were elucidated by means of 1D, 2 D NMR and HR-mass spectroscopy. Compounds 2-5 are known compounds but not previously isolated from the resin of C. MYRRHA. Compounds 4 and 5 exhibited significant aromatase inhibiting activity with IC50 values at 0.2 microM and 0.3 microM, respectively. As shown in the MTT assay, 2, 3, 4, and 5 had inhibitory effects on HUVEC growth with IC50 values of 0.122 microM (2), 0.125 microM (3), 0.069 microM (5). Compounds 1-5 did not inhibit contraction of the isolated uterine and did not protect HUVEC from damage induced by H2O2 at the tested concentration.

    Address: Jiangsu Key Laboratory for TCM Formulae Research, Nanjing University of Chinese Medicine, Nanjing, Personal Record China.
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    J. Nat. Prod., 2000 vol. 63(6) pp. 817-20
    Potential antitumor-promoting diterpenoids from the stem bark of Picea glehni

    Kinouchi, Y; Ohtsu, H; Tokuda, H; Nishino, H; Matsunaga, S; Tanaka, R
    A novel rearranged labdane-type diterpenoid, 19(4-->3)abeo-8alpha, 13(S)-epoxylabda-4(18),14-diene (1), and two new abietane-type diterpenoids, 19-nor-abieta-4(18),8,11,13-tetraen-7-one (2) and 12-hydroxydehydroabietic acid (3) were isolated from the stem bark of Picea glehni, together with seven known diterpenoids-13-epimanoyl oxide (4), dehydroabietic acid (5), (11E)-14, 15-bisnor-8alpha-hydroxy-11-labden-13-one (6), abieta-8,11, 13-trien-7-one (7), 9alpha,13alpha-epidioxyabiet-8(14)-en-18-oic acid (8), 9,10alpha-epoxy-9,10-seco-abieta-8,11,13-trien-18-oic acid (9), and methyl 15-hydroxy-7-oxo-dehydroabietate (10). Compounds 5-8 and 10 showed potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate.
    Address: Department of Medicinal Chemistry, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan.

    Planta Med., 1999 vol. 65(7) pp. 664-6
    Anti-tumor-promoting rearranged abietane diterpenes from the leaves of Larix kaempferi
    Ohtsu, H; Tanaka, R; Matsunaga, S; Tokuda, H; Nishino, H
    Two novel rearranged abietane-type diterpene acids, karamatsuic acid (1) and larikaempferic acid (2) were isolated as their corresponding methyl esters, 1a and 2a, from the leaves of Larix kaempferi (Lamb.) Carr. Their structures were established as 9,10 alpha-epoxy-9,10-seco-abieta-8,11,13-trien-18-oic acid and 9 alpha,13 alpha-epoxy-8-oxo-9(8-->7)abeo-7 beta H-abietan-18-oic acid, respectively, by spectral evidence. Compounds 1a, 2a and 12,15-dihydroxydehydroabietic acid (3) exhibited potent inhibitory effects against 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced Epstein-Barr virus early antigen (EBV-EA) activation in Raji cells.

    http://tapatalk.com/tapatalk_image.p...YWJ5Zy5qcGc%3D

    now pay me...stole the whole thing, similar to formestane maybe
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    I wonder how it converts in the body.
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    I shall also award rep points for relevant studies.

    Mine go a little further.
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    Also if interested I will rep every person who negs bdcc
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    Quote Originally Posted by FL3X MAGNUM View Post
    Also if interested I will rep every person who negs bdcc
    You are picking the wrong battle, my friend.

    I have the largest e-penis in all of Anabolic Minds land outside of Admin.

    His is huge.
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    Quote Originally Posted by bdcc View Post

    You are picking the wrong battle, my friend.

    I have the largest e-penis in all of Anabolic Minds land outside of Admin.

    His is huge.
    We are many
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    Will it be easier on the joints?
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    Quote Originally Posted by T-Bone View Post
    Will it be easier on the joints?
    Unlikely, the whole idea is estrogen control which is the cause of drying out. Unless PES worked a lot of magic
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    Definitely excited to get my hands on this new formula! Looking forward to the full write up coop.
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    Quote Originally Posted by Driven2lift View Post
    Unlikely, the whole idea is estrogen control which is the cause of drying out. Unless PES worked a lot of magic
    It will be significantly lighter on the joints. That was the primary complaint in v1, so we worked some "magic."

    Start here: http://www.ncbi.nlm.nih.gov/pubmed/18267111

    This is the same MOA used by zingerone (found in Epharm Joint force -> http://www.ncbi.nlm.nih.gov/pubmed/19459736)
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    Quote Originally Posted by mr.cooper69 View Post

    It will be significantly lighter on the joints. That was the primary complaint in v1, so we worked some "magic."

    Start here: http://www.ncbi.nlm.nih.gov/pubmed/18267111

    This is the same MOA used by zingerone (found in Epharm Joint force -> http://www.ncbi.nlm.nih.gov/pubmed/19459736)
    Only Cooper can make me excited to be wrong.
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    Sounds like I need to try it then.
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    Quote Originally Posted by T-Bone View Post
    Sounds like I need to try it then.
    I would love to hear your response to it. I do remember your feedback on erase pro about joint issues. Sounds like this was formulated perfectly for you!
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    Quote Originally Posted by LiveToLift View Post
    I would love to hear your response to it. I do remember your feedback on erase pro about joint issues. Sounds like this was formulated perfectly for you!
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    Quote Originally Posted by mr.cooper69 View Post

    It will be significantly lighter on the joints. That was the primary complaint in v1, so we worked some "magic."

    Start here: http://www.ncbi.nlm.nih.gov/pubmed/18267111

    This is the same MOA used by zingerone (found in Epharm Joint force -> http://www.ncbi.nlm.nih.gov/pubmed/19459736)
    Awesome Cy
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    J Ethnopharmacol. 2009 Nov 12;126(2):221-5. doi: 10.1016/j.jep.2009.08.041. Epub 2009 Aug 31.
    An in vitro study on antiproliferative and antiestrogenic effects of Boerhaavia diffusa L. extracts.
    Sreeja S, Sreeja S.
    Source
    Cancer Endocrinology, Integrated Cancer Research Programme, Rajiv Gandhi Centre for Biotechnology, Thycaud P.O., Thiruvananthapuram, Kerala 695014, India.
    Abstract
    ETHNOPHARMACOLOGICAL RELEVANCE:
    Boerhaavia diffusa L. (Nyctinaceae) is a plant of tropical region used in Indian traditional medicine for the treatment of human ailments including abdominal tumor, jaundice, dyspepsia, menstrual disorders, etc. This plant also has antilymphoproliferative, antimetastatic and immunomodulatory effects.
    AIM OF THE STUDY:
    This study aimed to assess the antiproliferative and antiestrogenic properties of methanol extract of Boerhaavia diffusa (BME) in MCF-7 breast cancer cell lines.
    MATERIALS AND METHODS:
    The effective concentration range of BME on cell viability was analyzed using MTT assay. Hydroxylapatite assay (HAP) was carried out to confirm the competitive binding of BME to the estrogen receptor (ER). The effect of BME on the expression of a selected estrogen responsive gene pS2 was analyzed by RT-PCR. The ability of BME to alter the cell cycle phases and distributions were studied using FACS analysis.
    RESULTS:
    Treatment with varying concentrations of BME (20-320 microg/mL) resulted in moderate to very strong growth inhibition in MCF-7 cell lines. BME competed with [(3)H]-estradiol for binding to ER with IC(50) value of 320 +/- 25 microg/mL. RT-PCR analysis revealed that BME reduced the mRNA expression of pS2 indicating the antiestrogenic action of BME. BME treatment for 48 h resulted in a remarkable increase in the number of MCF-7 cells in the G0-G1 fraction from 69.1% to 75.8%, with a reciprocal decrease of cells in all other phases indicating cell cycle arrest at G0-G1 phase.
    CONCLUSIONS:
    The results demonstrate that Boerhaavia diffusa possess antiproliferative and antiestrogenic properties and suggest that it may have therapeutic potential in estrogen dependent breast cancers.
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    Is the new AI still suicidal?
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    I never had joint issues running EP and 1 or 2 caps of Erase together. Guess I should consider myself very lucky. Still very intrigued by this new formula.
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    Quote Originally Posted by JM1437 View Post
    I never had joint issues running EP and 1 or 2 caps of Erase together. Guess I should consider myself very lucky. Still very intrigued by this new formula.
    I had very minor joint pain the first run with EPRO but it tapered and I hadn't had it since. Loved every minute of being on it. Very excited to try this new formula. Nothing better then the leaning and drying out I experience from the stuff.
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    Will there be an intro-sale?
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    Quote Originally Posted by The Engineer View Post
    Will there be an intro-sale?

    According to the red writing there will be.
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    Quote Originally Posted by JM1437 View Post
    I never had joint issues running EP and 1 or 2 caps of Erase together. Guess I should consider myself very lucky. Still very intrigued by this new formula.
    Same here although I've never stacked the two.
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    Quote Originally Posted by money0351 View Post
    Same here although I've never stacked the two.
    I'm pretty sure the reps would be obligated to say you probably should't run them together but if you are like me and don't get joint issues I'd highly recommend stacking EP with 1 or 2 caps of Erase.
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    Quote Originally Posted by JM1437 View Post
    I'm pretty sure the reps would be obligated to say you probably should't run them together but if you are like me and don't get joint issues I'd highly recommend stacking EP with 1 or 2 caps of Erase.

    So 100-125 mg of Androst-3,5-dien-7,17-dione?. I don't know about that, more isn't better....
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    Quote Originally Posted by T-Bone View Post
    So 100-125 mg of Androst-3,5-dien-7,17-dione?. I don't know about that, more isn't better....
    Oh I know I just experimented. Running 1 cap EP and 1 cap Erase daily is where I saw the best results.
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    The worst joint pain I ever suffered from Erase was some mild tendonitis in my wrist and elbow. It happened a couple of times and I have used many, many bottles.

    I too am one of the lucky ones.
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    Quote Originally Posted by bdcc View Post
    The worst joint pain I ever suffered from Erase was some mild tendonitis in my wrist and elbow. It happened a couple of times and I have used many, many bottles. I too am one of the lucky ones.
    Nothing a good joint support can't prevent I'm sure. It is very obvious you are a true erase addict!
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    I am one of the unlucky individuals who's physique benefits greatly from lowering estrogen but unfortunately I become more injury prone if I overdo it, this goes for anything "DRY." This new formula looks interesting hope this is a homerun for you guys.
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    Quote Originally Posted by Driven2lift View Post
    Is the new AI still suicidal?
    Bumping this
    "no failure is final, nor is any success"
    Follow my 2014 training and supps!
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    Quote Originally Posted by chedapalooza View Post

    Bumping this
    Calling mr cooper: is the new erase pro still a suicidal AI?
    "no failure is final, nor is any success"
    Follow my 2014 training and supps!
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    Great insider deal on erase pro. Check it out in the latest insider email!
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    I'll pass. Would've been better without the protein.
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    Quote Originally Posted by halfhuman View Post
    I'll pass. Would've been better without the protein.
    Considering the protein is practically free I think it's a win in any case.
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    Quote Originally Posted by LiveToLift View Post
    Considering the protein is practically free I think it's a win in any case.
    Yea and no. I rather pay around $30 for the erase insider deal without the protein. But not bad if someone wants the protein
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    The insider was a great deal! Imo better than the NP new years sale
    USPLABS4LIFE!!

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