Need suggestions from members who have gotten off Klonopin

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  1. Getting off Klon is easy. I took it for years, 2mg/d.

    First of all, it has a long half-life. This makes it convenient but also undesirable for long-term use. Replacing it with a shorter acting benzo is something to consider, so you may wish to discuss that with your doc. A long half-life = greater enzymatic involvement, greater receptor up-regulation, etc.. which equates to faster tolerance and higher addiction potential. If you're just taking it for stress then something like lorazepam might work equally well for about the same dose and only 1/3 the duration of action. Diazepam has a nice short half-life too, but also a much higher dose requirement, making it a less efficient replacement option if the goal is to minimize.

    Second, situational use is something to think about. If you don't have a chronic medical condition (like seizure) then why are you using it chronically? If you'd like to still treat the stress with a benzo, but are also serious about limiting dependency, using on a situational basis only seems like an obvious strategy.

    Also, if you'd like to get off of RXs completely, there are many potential alternatives which are natural and can attenuating withdrawal while also providing decent GABAnergic activity.
    "...The sole test of the validity of any idea is experiment." - Feynman


  2. Just to clarify:

    Diazepam(Valium) has a MUCH longer half-life than Klonopin. Klonopin is mainly prescribed for anxiety due to is somewhat long half-life. Ones like Alprazolam(Xanax) Lorazepam(Ativan) are used to seizures and panic attacks due to their quick onset.

    But again, be careful getting off of benzos. Just like with alcohol, the withdrawals can kill you (DT's).
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  3. Quote Originally Posted by Brandinooooo View Post
    Just to clarify:

    Diazepam(Valium) has a MUCH longer half-life than Klonopin. Klonopin is mainly prescribed for anxiety due to is somewhat long half-life. Ones like Alprazolam(Xanax) Lorazepam(Ativan) are used to seizures and panic attacks due to their quick onset.

    But again, be careful getting off of benzos. Just like with alcohol, the withdrawals can kill you (DT's).
    Yes, thank you for correcting my generalization. Indeed, diazepam has some relatively long-lived actives. Though the long terminal values are generally misleading, as one could anticipated with a look at the comparatively short values of it's marketed metabolites. Things like temazepam, oxazepam, and even pro-metabolites like clorazepate (which demonstrates significantly longer duration when compared to diazepam, but you probably wouldn't guess it just looking at the numbers.)

    So yes, it would be more accurately stated from a 'clinical perspective', but I'd still classify the effective duration of diazepam below Klonipin and certainly below Xanax as well.

    And just to clarify further, clonazepam was originally marketed specifically for treatment of seizure. While it's off-label utility as an anxiolytic has become popular, and may account for the majority of it's prescriptions as you mentioned, situations like the OP now finds himself in are a obvious testimony to the perils of trading application efficiency for dosing convenience.
    "...The sole test of the validity of any idea is experiment." - Feynman
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