absorption rates

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    absorption rates


    Is there a difference in absorption rate between 100mg cypionate test in 2cc- 50mg/cc and 100mg cypionate test in 1cc- 100mg/cc and 100mg cypionate test in .5cc- 200mg/cc? All same esther but will they absorb at same rate since they have different amounts of carriers (oil)? Technically they should but there's probably some variation?

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    Maybe it sounds stupid. Just wondering if anyone has experienced a difference within the same esther but different potency.
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    Good question, I'm interested too. While I think there may be a slight difference in times because of the different amounts of carriers I don't think it'll be of significance given the onset time of the cyp
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    No it is the same times brother. The amount in the carrier doesn't matter. Once the oil is injected it creates a Depot (like a pocket) and your body attacks that pocket and starts absorbing it. Weather it's 1cc or 4cc your body will absorb it at the same rate. Now once it is broken down your body takes in those bound molecules. (Test bound to cyp ester) and cleaves off the ester making the test free to be absorbed. The rate at which your body frees the steroid from the ester is the same and is determined by your genetics.

    Hope that helps
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    Name:  nandromol.gif
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Size:  19.0 KBAccording to this study the amount of carrier affects the absorption rates. The total dose of each injection was 100mg of Nandrolone but the volume varied. The stronger concentration released from depot at higher amounts.
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    Quote Originally Posted by bad rad View Post
    <img src="http://anabolicminds.com/forum/attachment.php?attachmentid=10 3615"/>According to this study the amount of carrier affects the absorption rates. The total dose of each injection was 100mg of Nandrolone but the volume varied. The stronger concentration released from depot at higher amounts.
    Awesome. I have never seen that from my studies. I have read mixed things and me and DH had a lengthy discussion about our theory behind ester release and how it doesn't truly effect halflife as much as thought. Good **** bro thanks for sharing
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    Quote Originally Posted by DangerDave View Post

    Awesome. I have never seen that from my studies. I have read mixed things and me and DH had a lengthy discussion about our theory behind ester release and how it doesn't truly effect halflife as much as thought. Good **** bro thanks for sharing
    I'm looking at the decanoate Esther at 4ml and 1ml. The more potent formula seems to absorb better all around. More gets absorbed but same rates. The time is same. More potent stuff is maybe more bioavailable or something but the esther is the determining factor when it comes to rate. Good stuff
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    There has to be something to the injection volume affecting release rates also. Nebibo (test undecanoate) only has the 13 week active life when injected 4cc in a single site. There's a newer version running trials in the States that's 3cc total volume and the active life is coming in at 10 weeks. Both preparations are 250mg/mL.
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    Quote Originally Posted by bad rad View Post
    There has to be something to the injection volume affecting release rates also. Nebibo (test undecanoate) only has the 13 week active life when injected 4cc in a single site. There's a newer version running trials in the States that's 3cc total volume and the active life is coming in at 10 weeks. Both preparations are 250mg/mL.
    Well the graphic shows SOME differences so maybe by the end of it's life there's that much difference in active lifetime. Absorption seems about the same. The more potent stuff starts out absorbing more overall but appears to fall off while the less potent with more fluid lingers around longer... makes sense.
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    and all of this is totally insignificant with the dosing schedule we use injecting 2x/week as we would with cyp. Very quickly it all comes out in the wash and blood levels are essentially the same, but it is very interesting to discuss. It similar to the prop is stronger theory that is not true as fairly quickly long esters actually achieve slightly higher blood levels than short ones , albeit to a totally insignificant clinical level.
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    Exactly... I had seen that chart before along with some others. Your explanation was right on. You can play with scenarios like which is better, shooting 400cc in the delt or 200cc in each dealt? Or if you inject 1000cc will it have the same half life as a 100cc? (I'm using cc instead of mgs since we talking about the preservation of the depot and "time" release, regardless of the steroid molecule). The OP's examples are a bit confusing, but I think he's asking these type of questions. Otherwise if you inject 200mg/mL or 300mg/mL the release is identical, as you said. But I think we agree that half lives are really the point where the steroid has exhausted it's useful life.

    Quote Originally Posted by DangerDave View Post
    Awesome. I have never seen that from my studies. I have read mixed things and me and DH had a lengthy discussion about our theory behind ester release and how it doesn't truly effect halflife as much as thought. Good **** bro thanks for sharing
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    Are you saying that injecting 100mgs of suspension ED is essentially the same as injecting 500mgs of test c EW? Or 100mgs of prop is the same?

    Quote Originally Posted by StanleyG View Post
    and all of this is totally insignificant with the dosing schedule we use injecting 2x/week as we would with cyp. Very quickly it all comes out in the wash and blood levels are essentially the same, but it is very interesting to discuss. It similar to the prop is stronger theory that is not true as fairly quickly long esters actually achieve slightly higher blood levels than short ones , albeit to a totally insignificant clinical level.
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    Quote Originally Posted by DetroitHammer View Post
    Are you saying that injecting 100mgs of suspension ED is essentially the same as injecting 500mgs of test c EW? Or 100mgs of prop is the same?
    Suspension has no ester - completely different scenario. Im saying exactly what I said - nothing more.
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    Quote Originally Posted by StanleyG View Post
    Suspension has no ester - completely different scenario. Im saying exactly what I said - nothing more.
    I know suspension has no ester. I'm trying to figure out your theory. You may not want to say more, but without saying more you are totally wrong.
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    Quote Originally Posted by DetroitHammer View Post
    I know suspension has no ester. I'm trying to figure out your theory. You may not want to say more, but without saying more you are totally wrong.
    Its not my theory it is a fact. With the dosing schedules adapted (ie long esters 2x/week) you will achieve slightly higher blood levels with e or c over time than you will with prop. at the same weekly dosages and we are talking weeks not months. The difference is clinically insignificant but that is the fact of the matter.
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    Clinical studies are a lot of things, but "factual" they are not. Regardless, I think I understand what you are saying. I have to go to work now. This evening I'll address this in more detail. As long as we agree that 100mgs of prop does not yield the same amount of test that 100mgs of Cyp, then the rest is almost moot.

    Quote Originally Posted by StanleyG View Post
    Its not my theory it is a fact. With the dosing schedules adapted (ie long esters 2x/week) you will achieve slightly higher blood levels with e or c over time than you will with prop. at the same weekly dosages and we are talking weeks not months. The difference is clinically insignificant but that is the fact of the matter.
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    My question was about the volume of the depot effecting the absorption rate. Same esther. 200mg in 1cc or 200mg in 2cc.
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    Quote Originally Posted by bad rad View Post
    There has to be something to the injection volume affecting release rates also. Nebibo (test undecanoate) only has the 13 week active life when injected 4cc in a single site. There's a newer version running trials in the States that's 3cc total volume and the active life is coming in at 10 weeks. Both preparations are 250mg/mL.
    If both are 250mg/ml and one is 4ml and the other is 3ml then of course there's going to be a difference in active life cuz ones bigger than the other
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    Quote Originally Posted by Yolked View Post
    If both are 250mg/ml and one is 4ml and the other is 3ml then of course there's going to be a difference in active life cuz ones bigger than the other
    That's what I was alluding to. Those two preparations really long active lives only when injected in that volume. The clearance rate tends to hold steady with both but it's just shorter with the smaller injection.
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