Skip mouthwash w/ nitrates..

  1. Advanced Member
    mcc23's Avatar
    Stats
    5'10"  175 lbs.
    Join Date
    May 2012
    Posts
    561
    Rep Power
    76425
    Level
    30
    Lv. Percent
    61.2%
    Achievements Activity Pro

    Skip mouthwash w/ nitrates..


    Interesting read claiming that mouthwash kills the salivary bacteria that converts nitrates to nitrites.

    w w w .ncbi.nlm.nih.gov/pubmed/18793740


    Recent studies surprisingly show that dietary inorganic nitrate, abundant in vegetables, can be metabolized in vivo to form nitrite and then bioactive nitric oxide. A reduction in blood pressure was recently noted in healthy volunteers after dietary supplementation with nitrate; an effect consistent with formation of vasodilatory nitric oxide. Oral bacteria have been suggested to play a role in bioactivation of nitrate by first reducing it to the more reactive anion nitrite. In a cross-over designed study in seven healthy volunteers we examined the effects of a commercially available chlorhexidine-containing antibacterial mouthwash on salivary and plasma levels of nitrite measured after an oral intake of sodium nitrate (10mg/kg dissolved in water). In the control situation the salivary and plasma levels of nitrate and nitrite increased greatly after the nitrate load. Rinsing the mouth with the antibacterial mouthwash prior to the nitrate load had no effect on nitrate accumulation in saliva or plasma but abolished its conversion to nitrite in saliva and markedly attenuated the rise in plasma nitrite. We conclude that the acute increase in plasma nitrite seen after a nitrate load is critically dependent on nitrate reduction in the oral cavity by commensal bacteria. The removal of these bacteria with an antibacterial mouthwash will very likely attenuate the NO-dependent biological effects of dietary nitrate.

  2. Senior Member
    cumminslifter's Avatar
    Stats
    6'1"  200 lbs.
    Join Date
    Feb 2013
    Age
    21
    Posts
    2,289
    Rep Power
    2227478
    Level
    61
    Lv. Percent
    49.23%
    Achievements Activity AuthorityActivity ProPosting Pro

    so Listerine before nitrates? lol
    1200 pound club
  3. Advanced Member
    mcc23's Avatar
    Stats
    5'10"  175 lbs.
    Join Date
    May 2012
    Posts
    561
    Rep Power
    76425
    Level
    30
    Lv. Percent
    61.2%
    Achievements Activity Pro

    no.. don't use mouthwash. the bacteria in the mouth are important for the conversion of nitrates to nitrites
    •   
       

  4. Senior Member
    cumminslifter's Avatar
    Stats
    6'1"  200 lbs.
    Join Date
    Feb 2013
    Age
    21
    Posts
    2,289
    Rep Power
    2227478
    Level
    61
    Lv. Percent
    49.23%
    Achievements Activity AuthorityActivity ProPosting Pro

    Quote Originally Posted by mcc23 View Post
    no.. don't use mouthwash. the bacteria in the mouth are important for the conversion of nitrates to nitrites
    ahh got ya
    1200 pound club
  5. Elite Member
    Jiigzz's Avatar
    Stats
    5'10"  205 lbs.
    Join Date
    Mar 2012
    Posts
    6,350
    Rep Power
    7699976
    Level
    94
    Lv. Percent
    25.61%
    Achievements Activity RoyaltyActivity AuthorityActivity ProActivity VeteranPosting Pro

    Quote Originally Posted by mcc23 View Post
    Interesting read claiming that mouthwash kills the salivary bacteria that converts nitrates to nitrites.

    w w w .ncbi.nlm.nih.gov/pubmed/18793740


    Recent studies surprisingly show that dietary inorganic nitrate, abundant in vegetables, can be metabolized in vivo to form nitrite and then bioactive nitric oxide. A reduction in blood pressure was recently noted in healthy volunteers after dietary supplementation with nitrate; an effect consistent with formation of vasodilatory nitric oxide. Oral bacteria have been suggested to play a role in bioactivation of nitrate by first reducing it to the more reactive anion nitrite. In a cross-over designed study in seven healthy volunteers we examined the effects of a commercially available chlorhexidine-containing antibacterial mouthwash on salivary and plasma levels of nitrite measured after an oral intake of sodium nitrate (10mg/kg dissolved in water). In the control situation the salivary and plasma levels of nitrate and nitrite increased greatly after the nitrate load. Rinsing the mouth with the antibacterial mouthwash prior to the nitrate load had no effect on nitrate accumulation in saliva or plasma but abolished its conversion to nitrite in saliva and markedly attenuated the rise in plasma nitrite. We conclude that the acute increase in plasma nitrite seen after a nitrate load is critically dependent on nitrate reduction in the oral cavity by commensal bacteria. The removal of these bacteria with an antibacterial mouthwash will very likely attenuate the NO-dependent biological effects of dietary nitrate.
    Yeah this. Bad oral hygiene can also blunt the effects of Nitrates.
  6. Senior Member
    PuZo's Avatar
    Stats
    6'2"  188 lbs.
    Join Date
    Apr 2010
    Posts
    1,438
    Rep Power
    412210
    Level
    37
    Lv. Percent
    46.57%
    Achievements Activity ProPosting Pro

    So this only applies for powdered products?
    iForce Nutrition Representative
    iTrain. iCompete. iDominate…iForce!
    www.iforcenutrition.com
  7. Elite Member
    Jiigzz's Avatar
    Stats
    5'10"  205 lbs.
    Join Date
    Mar 2012
    Posts
    6,350
    Rep Power
    7699976
    Level
    94
    Lv. Percent
    25.61%
    Achievements Activity RoyaltyActivity AuthorityActivity ProActivity VeteranPosting Pro

    Nitrates in general.
  

  
 

Similar Forum Threads

  1. Skipping a few days of injections on test E?
    By UberPooper1 in forum Anabolics
    Replies: 2
    Last Post: 10-21-2005, 10:18 PM
  2. I work in construction, can I skip cardio?
    By Doko in forum Exercise Science
    Replies: 3
    Last Post: 06-16-2005, 10:25 AM
  3. Can I skip rows?
    By Moyer in forum Exercise Science
    Replies: 17
    Last Post: 04-09-2005, 10:16 AM
  4. breakdown of andro nitrate fuel from twinlab?
    By xarmyguy26 in forum Anabolics
    Replies: 5
    Last Post: 11-28-2003, 12:07 PM
Log in
Log in