Semax

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  1. Great info, any issues with the NA you know of?

  2. Semax


    Quote Originally Posted by sespress View Post
    Great info, any issues with the NA you know of?
    No, I will eventually try all 3 versions. It's that I already have the original and Na-Semax Amidate in the fridge. NA-Semax will be the one I try last. It's suppose to be the most stimulating version.
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  3. great input here bro

    thank you
    Vein Nutrition Rep InstaGram Smith_69_16
    https://www.veinnutrition.com/
    Use code Smith10 for 10% off your order

  4. Quote Originally Posted by smith_69 View Post
    great input here bro

    thank you
    completely agree with this!
    Shoot me a PM whenever you get a chance, would like to know where you are getting this from. Started to read through some reddit threads and a few other articles and seems like a very intresting noot to try out

  5. Quote Originally Posted by ELROCK View Post
    No, I will eventually try all 3 versions. It's that I already have the original and Na-Semax Amidate in the fridge. NA-Semax will be the one I try last. It's suppose to be the most stimulating version.
    That's great. Looking forward to the comparsion. Wanted to buy some but didn't know how to choose so I'll wait for your feedback.
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  6. The pre-made Semax nasal spray only lasted me 16 days which makes it really not cost effective for me. I started with two sprays then upped it to 4 sprays. I took a few days off and then started up the NASA. I will update my opinion on it in a few days with more regular use.

  7. Quote Originally Posted by ELROCK View Post
    Clear you box
    Can I get a PM?

    Quote Originally Posted by ELROCK View Post
    After using regular Semax for 9 days now I feel I can give my opinion on it.

    Many people report all day mood boost and compare it to a longer lasting post workout or post cardio endorphin glow from Semax. Many people report slight stimulation, productivity and focus. Many people report higher functioning tasks and learning becomes easier.

    Honestly, I was expecting more out of Semax since it is considered one of the best nootropics to date by many in the noot community. I don't get a change in mood nor do I get a noticeable increase in focus. What I notice is subtle stimulation and an improvement in productivity. The productivity is not really noticeable throughout the day, but when I look back on the day I seem to have accomplished more then I normally would have (subjectively). I have been impressed with my productivity level at the end of each day since starting Semax. I feel Semax stacks well with stims and many other noots. The issue I have with it is it is not strong enough on its own for me and so that makes it too costly to use. I am hoping the NA-Semax and/or the NA-Semax Amidate are decent improvements to the original Semax. I will post up my opinion on NA-Semax Amidate once I start that next month.

    Recap on my experience so far:

    Pros:
    -increased productivity
    -slight stimulation (subtle wakefulness "refreshed" feel)

    Cons:
    -no mood improvement
    -no noticeable increase in focus.
    -no verbal fluency noted.
    -costly
    -Needs/should be stacked IMO
    -not very stable peptide (must handle with care) which is a down side IMO (needs to be stored in the fridge.)
    -not orally viable (needs to be administered nasally or by injecting).
    Great review.

    Can I ask how ared you dosing the Semax and are you using the Semax Spray??

    Interested in how the NA-Semax Amidate treats you.

  8. So there might be a link between semax and cortisol based on its looking like a fragment of an adrenal agent. Not sure about that, I'm on a 7-keto product right now so it would cancel out but if be interested if weight gain occurs with habitual use.

  9. Quote Originally Posted by JohnP. View Post
    Can I get a PM?



    Great review.

    Can I ask how ared you dosing the Semax and are you using the Semax Spray??

    Interested in how the NA-Semax Amidate treats you.
    Using the nasal Semax spray I started with two sprays (one in each nostril) for the first 5 or 6 days. Then, moved up to 4 sprays (two in each nostril). I dose it in the morning.

  10. Quote Originally Posted by ELROCK View Post
    The pre-made Semax nasal spray only lasted me 16 days which makes it really not cost effective for me. I started with two sprays then upped it to 4 sprays. I took a few days off and then started up the NASA. I will update my opinion on it in a few days with more regular use.
    I ordered N-Acetyl Semax 98.73% spray in the 30mg size. That will give me 100 300mcg sprays. It's pretty awesome they ship in cold pack and separate too. I paid $62 dollars with 10% code which is not to bad. I will be posting my thoughts on it in this thread.

  11. Quote Originally Posted by JohnP. View Post
    I ordered N-Acetyl Semax 98.73% spray in the 30mg size. That will give me 100 300mcg sprays. It's pretty awesome they ship in cold pack and separate too. I paid $62 dollars with 10% code which is not to bad. I will be posting my thoughts on it in this thread.
    What's the 10% code?

  12. Quote Originally Posted by Hyperfluxe View Post
    What's the 10% code?
    check pm

  13. Quote Originally Posted by JohnP. View Post
    I ordered N-Acetyl Semax 98.73% spray in the 30mg size. That will give me 100 300mcg sprays. It's pretty awesome they ship in cold pack and separate too. I paid $62 dollars with 10% code which is not to bad. I will be posting my thoughts on it in this thread.
    Can I get the code too? Hope it still works.
  14. Semax


    Quote Originally Posted by ELROCK View Post
    After using regular Semax for 9 days now I feel I can give my opinion on it.

    Many people report all day mood boost and compare it to a longer lasting post workout or post cardio endorphin glow from Semax. Many people report slight stimulation, productivity and focus. Many people report higher functioning tasks and learning becomes easier.

    Honestly, I was expecting more out of Semax since it is considered one of the best nootropics to date by many in the noot community. I don't get a change in mood nor do I get a noticeable increase in focus. What I notice is subtle stimulation and an improvement in productivity. The productivity is not really noticeable throughout the day, but when I look back on the day I seem to have accomplished more then I normally would have (subjectively). I have been impressed with my productivity level at the end of each day since starting Semax. I feel Semax stacks well with stims and many other noots. The issue I have with it is it is not strong enough on its own for me and so that makes it too costly to use. I am hoping the NA-Semax and/or the NA-Semax Amidate are decent improvements to the original Semax. I will post up my opinion on NA-Semax Amidate once I start that next month.

    Recap on my experience so far:

    Pros:
    -increased productivity
    -slight stimulation (subtle wakefulness "refreshed" feel)

    Cons:
    -no mood improvement
    -no noticeable increase in focus.
    -no verbal fluency noted.
    -costly
    -Needs/should be stacked IMO
    -not very stable peptide (must handle with care) which is a down side IMO (needs to be stored in the fridge.)
    -not orally viable (needs to be administered nasally or by injecting).
    I wanted to update with my experience with the NASA version. Sorry, for the delay, but I literally just finished off the bottle. I took a little longer break between bottles and I had the holidays and a vacation mixed in there. This bottle was not used everyday like the regular Semax was used so that's definitely worth noting. I will say that this too was subtle, but effective. It works for keeping me productive throughout the day. Personally, I didn't notice any real difference in this version verse the original version. It mixed well with Modafinil for a long productive day. Modafinil makes me a bit edgy and impatient. Taking NASA with the Modafinil helps smooth it out. My favorite brain stack for very occasional use is NASA (3 sprays), Tianeptine sulphate (25-50 mg), Modafinil (100 mg) and a cup of coffee. It makes for a very productive and enjoyable day.

    Will I be repurchasing the NASA? I am still not sure. It is helpful, but it's subtle enough to have me think it's not somethings I need. I will try the last NA-Semax down the road so I can see which one I like best. If someone were to ask me which one I like better I would say buy whichever one is on sale and less expensive because they are still very similar IME. I also want to mention that supplements in general effect people differently and especially with noots because we all have different brain chemistry. This was simply just my experience that I wanted to share with the community.

  15. Hey! I enjoyed the NA version myself although I didn't have the regular before to compare it with. Anyways I ended up doing like almost the same thing (really crazy that) NA semax and floromodafanil (diff there) and coffee! Coffee makes both incredible, much better like adding some fuel injector cleaner into an old engine. Ran smooth the whole time. I am gonna reorder it but I'll be taking a break to. Mostly cash related, I just started a peptide run.

    Did you feel any downside to your stack? I had a few jitters at the begging but got used to it. I think maybe it burned a bit on the spray but not enough to deter me.

  16. Quote Originally Posted by sespress View Post
    Hey! I enjoyed the NA version myself although I didn't have the regular before to compare it with. Anyways I ended up doing like almost the same thing (really crazy that) NA semax and floromodafanil (diff there) and coffee! Coffee makes both incredible, much better like adding some fuel injector cleaner into an old engine. Ran smooth the whole time. I am gonna reorder it but I'll be taking a break to. Mostly cash related, I just started a peptide run.

    Did you feel any downside to your stack? I had a few jitters at the begging but got used to it. I think maybe it burned a bit on the spray but not enough to deter me.
    Nice! I didn't have any negative sides from it. The NA-Semax is suppose to be the most stimulating version.

  17. My NA Semax run was great. I did 600mcgs a day-2 sprays, 1 per nostril in the morning. The 1st 4 or 5 days I felt very slight jitters. I did stack both Phenylpiracetam or Armodafinil with it 1 time a week. I also drank coffee with my daily dose. NA Semax is most effective nootropic I have used by far. Everything I got from noopept but way more amplified. I'm noticing that HD vision with and a big increase in mental clarity. No negative sides for me.

    Next up for me is PRL 8 53
  18. Semax


    Quote Originally Posted by JohnP. View Post
    My NA Semax run was great. I did 600mcgs a day-2 sprays, 1 per nostril in the morning. The 1st 4 or 5 days I felt very slight jitters. I did stack both Phenylpiracetam or Armodafinil with it 1 time a week. I also drank coffee with my daily dose. NA Semax is most effective nootropic I have used by far. Everything I got from noopept but way more amplified. I'm noticing that HD vision with and a big increase in mental clarity. No negative sides for me.

    Next up for me is PRL 8 53
    You will have to let us know how the PRL 8-53 works for you. I looked into it, but haven't pulled the trigger on it yet.

  19. Quote Originally Posted by ELROCK View Post
    You will have to let us know how the PRL 8-53 works for you. I looked into it, but haven't pulled the trigger on it yet.
    I have used it for 3 days now.The hardest part is getting the powder out of the bottle to measure the 15mgs. I should have made a solution with it.

  20. Been using NASemaxA @600mcg for a week now. It is everything that I expect out of a nootropic, wow. I'm stacking it with P21 so there may be some crossover.

  21. Quote Originally Posted by Hyperfluxe View Post
    Been using NASemaxA @600mcg for a week now. It is everything that I expect out of a nootropic, wow. I'm stacking it with P21 so there may be some crossover.
    What are you noticing from P21? Is it a nasal spray?

  22. Whoa lots of p stuff tossed around here, these related or... What are they?

  23. Quote Originally Posted by sespress View Post
    Whoa lots of p stuff tossed around here, these related or... What are they?
    PRL 853 and P21 are both nootropics.

    PRL 853- is a nootropic research chemical derived from benzoic acid and phenylmethylamine (Benzylamine) that has been shown to act as a hypermnesic drug in humans; it was first synthesized by medical chemistry professor Nikolaus Hansl at Creighton University in the 1970s as part of his work on amino ethyl meta benzoic acid esters

    A single study in humans was reported in 1978. The double-blind trial of PRL-8-53 in 47 healthy volunteers measured its effects on a variety of cognitive measures. 5 mg of the drug was administered orally 2–2.5 hours before the study tasks.Overall improvements in recollection differed based on how many words were recalled under placebo, with the poor performers (six words or fewer) experiencing a 87.5-105% increase in recollection and the high performers (eight or more words) a 7.9-14% increase which failed to reach statistical significance; when controlling for subjects over the age of 30 only, a 108-152% increase was noted. No side effects were reported during the trial.

    P21 Google Neurotrophic peptides incorporating adamantane improve learning and memory, promote neurogenesis and synaptic plasticity in mice

    Abstract
    Development of neurotrophic peptidergic drugs that can mimic neurotrophins and promote neurogenesis and maturation of newborn cells into mature functional neurons represents an exciting therapeutic opportunity for treatment of Alzheimer disease and other learning and memory disorders as well as enhancing cognition of normal individuals. Here we report the design of a peptidergic compound, Ac-DGGLAG-NH2, called P21, when administered peripherally, enhanced learning as well as both short-term and spatial reference memories of normal adult C57Bl6 mice. P21 induced enhancement of neurogenesis and maturation of newly born neurons in the granular cell layer and subgranular zone of the dentate gyrus.

  24. Quote Originally Posted by JohnP. View Post
    PRL 853 and P21 are both nootropics.

    PRL 853- is a nootropic research chemical derived from benzoic acid and phenylmethylamine (Benzylamine) that has been shown to act as a hypermnesic drug in humans; it was first synthesized by medical chemistry professor Nikolaus Hansl at Creighton University in the 1970s as part of his work on amino ethyl meta benzoic acid esters

    A single study in humans was reported in 1978. The double-blind trial of PRL-8-53 in 47 healthy volunteers measured its effects on a variety of cognitive measures. 5 mg of the drug was administered orally 22.5 hours before the study tasks.Overall improvements in recollection differed based on how many words were recalled under placebo, with the poor performers (six words or fewer) experiencing a 87.5-105% increase in recollection and the high performers (eight or more words) a 7.9-14% increase which failed to reach statistical significance; when controlling for subjects over the age of 30 only, a 108-152% increase was noted. No side effects were reported during the trial.

    P21 Google Neurotrophic peptides incorporating adamantane improve learning and memory, promote neurogenesis and synaptic plasticity in mice

    Abstract
    Development of neurotrophic peptidergic drugs that can mimic neurotrophins and promote neurogenesis and maturation of newborn cells into mature functional neurons represents an exciting therapeutic opportunity for treatment of Alzheimer disease and other learning and memory disorders as well as enhancing cognition of normal individuals. Here we report the design of a peptidergic compound, Ac-DGGLAG-NH2, called P21, when administered peripherally, enhanced learning as well as both short-term and spatial reference memories of normal adult C57Bl6 mice. P21 induced enhancement of neurogenesis and maturation of newly born neurons in the granular cell layer and subgranular zone of the dentate gyrus.
    I have been keeping an eye on both of these. I would like to give both of them a run. It seems PRL gets a little better user feedback then the P21. The P21 since it is newer and had less overall feedback, but it seems to be hit or miss with people. Some say they don't notice anything from it while others claim to love it. Did the PRL bring on any anxiety issues with you?
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