SARMS and their future in HRT
- 11-15-2007, 03:43 PM
- 11-15-2007, 11:09 PM
- 11-15-2007, 11:50 PM
SARMs provide the opportunity to design molecules that can be delivered orally, but that selectively target the androgen receptors in different tissues differently. The goal of research in this area is to allow a customized response: tissues that are the target of the therapy will respond as they would to testosterone; other tisses where undesirable side effects are produced will not. For example, if the target is bone growth in elderly men with osteopenia or osteoporosis, but with no overt signs of hypogonadism, an SARM targeting bone and muscle tissue, but with lesser activity on the prostate or testes would be more desirable.
11-16-2007, 09:47 PM
What about some of the more subjective issues like feelings of well being?
Could a SARM be designed to target receptors in the brain?
11-17-2007, 12:51 PM
If sarms act like testosterone then why not just use testosterone.
1) Injected testosterone shrinks testis and reduces spermatigenesis. Not true with Sarms?
2) Injected testosterone stimulates the prostate and can cause cancer. Not true with Sarms?
3) Your natural testosterone is threatened when using trt but not sarms?
4) Women can use sarms; but shouldn't use testosterone?
Please let me know if I'm wrong on any (or all) of these.
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