Dr John, hMG in conjunction with hCG?

  1. Dr John, hMG in conjunction with hCG?


    Just curious. I didn't see any mention of hMG in your protocol sticky's. I am reading about some of the very cutting edge people running hMG in conjunction with hCG. Boosts FSH and makes the testes more sensitive to hCG.

    I was curious to know if hMG is part of your protocol, your opinion, and if it is something you are possibly looking into as part of your TRT management protocols.


  2. Quote Originally Posted by plymouth city View Post
    Just curious. I didn't see any mention of hMG in your protocol sticky's. I am reading about some of the very cutting edge people running hMG in conjunction with hCG. Boosts FSH and makes the testes more sensitive to hCG.

    I was curious to know if hMG is part of your protocol, your opinion, and if it is something you are possibly looking into as part of your TRT management protocols.
    I think it's used more for fertility when trying to concieve.. Haven't seen it used in other cases, although it could be.

  3. Quote Originally Posted by plymouth city View Post
    Just curious. I didn't see any mention of hMG in your protocol sticky's. I am reading about some of the very cutting edge people running hMG in conjunction with hCG. Boosts FSH and makes the testes more sensitive to hCG.

    I was curious to know if hMG is part of your protocol, your opinion, and if it is something you are possibly looking into as part of your TRT management protocols.

    It's pretty costly from what I've seen.
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  4. It is actually approved in other countries for hypogonadism.

  5. Quote Originally Posted by griffinannie View Post
    It is actually approved in other countries for hypogonadism.
    Forgetting the price.
    Assuming men who is not trying to conceive
    what are the additional benefits if he already uses HCG?

    Any research along this line would be helpfull.

  6. Quote Originally Posted by JanSz View Post
    Forgetting the price.
    Assuming men who is not trying to conceive
    what are the additional benefits if he already uses HCG?

    Any research along this line would be helpfull.
    It is basically a mix of LH, FSH, and hCG. It adds to sensitivity of testicals and increases T even more while making the testes more sensitive to hCG.

    http://www.fertility.com/internation...nadotropin.jsp

  7. Quote Originally Posted by plymouth city View Post
    It is basically a mix of LH, FSH, and hCG. It adds to sensitivity of testicals and increases T even more while making the testes more sensitive to hCG.

    http://www.fertility.com/internation...nadotropin.jsp
    It would help if there was some independent test,
    by someone who do not care about fertility but do care about quality of life.

    Does it make one feel better
    does the balls hang better
    better erection
    better orgasm
    shorter refraction time

    which one?

  8. And if anybody has any online sources that require no prescription for HMG, please PM me.

  9. Quote Originally Posted by JanSz View Post
    It would help if there was some independent test,
    by someone who do not care about fertility but do care about quality of life.

    Does it make one feel better
    does the balls hang better
    better erection
    better orgasm
    shorter refraction time

    which one?
    JansZ, from the stuff Ive read, all of the above except refraction time.

    Refraction time and Prolactin go hand in hand.
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  11. Quote Originally Posted by plymouth city View Post
    It is basically a mix of LH, FSH, and hCG.

    I wonder if the source doesn't describe hMG incorrectly.

    As I understood from other sources, hMG is an analog of FSH in much the same way that hCG is an an analog of LH.

  12. Dr. John, if it's not confidential, don't you have a couple of patients on it? How do they like it?

  13. Quote Originally Posted by Dr. John View Post
    I have had a couple of guys who demended to try it. Both reported great results with respect to testicular size.

    There are LH receptors all over the body, so supplementing TRT patients (induced secondary hypogonadism) with HCG makes sense. But I am not aware of FSH activivity beyond the Sertoli cells (sperm factories) of the testes.

    It's quite expensive.
    That is the issue. So it is probably a cost versus benefit issue as far as using it on patients. The costs may outweigh the bennie's.

    I am understanding your logic as well here Dr John. With LH receptors throughout the body, increasing LH to boost T makes sense. Increasing FSH does not, unless your a guy looking to concieve.

    I will try and dig up the info about hMG boosting hCG's effectiveness. Alot of stuff I read I tend to keep jumping around and around without saving pages - I do not have my own computer, so I have no way of saving info.

    Thanks for your expert medical opinions, as always

  14. Quote Originally Posted by plymouth city View Post
    That is the issue. So it is probably a cost versus benefit issue as far as using it on patients. The costs may outweigh the bennie's.

    I am understanding your logic as well here Dr John. With LH receptors throughout the body, increasing LH to boost T makes sense. Increasing FSH does not, unless your a guy looking to concieve.

    I will try and dig up the info about hMG boosting hCG's effectiveness. Alot of stuff I read I tend to keep jumping around and around without saving pages - I do not have my own computer, so I have no way of saving info.
    Thanks for your expert medical opinions, as always
    Yes, you do;
    Keep collecting the reference on Notepd, Excel or Word, on the end e-mail it to yourself.

  15. Quote Originally Posted by plymouth city View Post
    That is the issue. So it is probably a cost versus benefit issue as far as using it on patients. The costs may outweigh the bennie's.

    I am understanding your logic as well here Dr John. With LH receptors throughout the body, increasing LH to boost T makes sense. Increasing FSH does not, unless your a guy looking to concieve.

    I will try and dig up the info about hMG boosting hCG's effectiveness. Alot of stuff I read I tend to keep jumping around and around without saving pages - I do not have my own computer, so I have no way of saving info.

    Thanks for your expert medical opinions, as always

    If hMG is a mix of FSH and hCG, using it w/ hCG effectively results in a larger dose of hCG. More hCG=greater response.

  16. Quote Originally Posted by Dr. John View Post
    I have had a couple of guys who demended to try it. Both reported great results with respect to testicular size.

    There are LH receptors all over the body, so supplementing TRT patients (induced secondary hypogonadism) with HCG makes sense. But I am not aware of FSH activivity beyond the Sertoli cells (sperm factories) of the testes.

    It's quite expensive.
    Does this show that fsh stimulates leydig cells? If so wouldn't hmg compliment hcg? This seems to show that fsh affects more than just sperm production.

    http://ajpendo.physiology.org/cgi/co...act/248/2/E176

    http://www.andrologyjournal.org/cgi/...tract/10/5/359

    "Sertoli cells produced an increase in the steroidogenic response of Leydig cells to hCG. Pretreatment of the coculture with pFSH enhanced the steroidogenic capacity of Leydig cells and increased the number of hCG receptors."

  17. Quote Originally Posted by mckinnj View Post
    Does this show that fsh stimulates leydig cells? If so wouldn't hmg compliment hcg? This seems to show that fsh affects more than just sperm production.

    http://ajpendo.physiology.org/cgi/co...act/248/2/E176

    http://www.andrologyjournal.org/cgi/...tract/10/5/359

    "Sertoli cells produced an increase in the steroidogenic response of Leydig cells to hCG. Pretreatment of the coculture with pFSH enhanced the steroidogenic capacity of Leydig cells and increased the number of hCG receptors."
    THANK YOU! This study echos a very similar study(which was probably the same study on a diff web page) that I read a week ago

    "Pretreatment of the coculture with pFSH enhanced the steroidogenic capacity of Leydig cells and increased the number of hCG receptors" - Which equals a more increased hCG resonse.
  

  
 

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