GOOD GOD you taking all that carntine is driving your choline in the freaken toilet. you may not care now but 1 year from now when you have a imbalanced liver you will. Carnitine depletes choline which is major building block for cell membrances as well neurotransmitter acteyl choline (aids in relaxation, digestion, libido,appeite, memory). Choline increases carnitine levels in tissue.
Get tested and see if you actually need it. Spectra cell intra cellular testing will tell you what you need and is covered by blue cross blue shield. or put it this way yes it cost 300 bucks for the test, but figure you can be wasting 300 bucks in 2-3 months on things you do not really need. and how much it could actually save u in the long run.
Please give me your references about this as I have never heard this "carnitine depletes choline" info.
Effects of L: -Acetylcarnitine on Cirrhotic Patients with Hepatic Coma: Randomized Double-Blind, Placebo-Controlled Trial.Malaguarnera M, Pistone G, Astuto M, Vecchio I, Raffaele R, Lo Giudice E, Rampello L.
Dipartimento di Scienze della Senescenza, Urologiche e Neurologiche, Universita di Catania, Via Messina 829, 95128, Catania, Italia,
[email protected].
Multiple therapeutic modalities have been used to treat hepatic encephalopathy. L: -Acetylcarnitine (LAC) is a physiologically active substance that improves both the energetic and the neurotransmission profiles. LAC is able to cross the hematoencephalic barrier and reach the cerebral regions, where the acetylic group may be utilized. The aim of this work was to evaluate the efficacy of LAC in the treatment of hepatic coma in cirrhotic patients. Twenty-four suitably selected patients were enrolled in the study and, following randomization, received either LAC (n=13) or placebo (n=11). Statistically significant differences in neurological findings, as evaluated by the Glasgow Scale, as well as in ammonia serum levels and BUN were found following LAC treatment. In the placebo group we observed two cases of improved neurological findings as well as one case of improved EEG grading. In the other group we observed an improvement of neurological findings and of EEG grade in 10 and 8 subjects, respectively. Noteworthily, seven (54%) patients went from grade 4 down to grade 3, and one from grade 4 down to grade 1. The improvement in the neurological picture was evident at between 1 and 4 hr after the end of treatment, remaining until 24 hr after. No side effects were observed in our study series. Our study demonstrates that LAC administration improved neurological and biohumoral symptoms in selective cirrhotic patients with hepatic coma.
PMID: 17080254 [PubMed - as supplied by publisher]
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Dec 13 2006 10:56:50
"No side effects were observed in our study series" I hardly think they would be giving this to these patients if what you said was true.
If choline (being a methyl donor )was depleted I agree that would be bad for anyone.