I’ve been peeling back some of the research on the IGF-I and cancer link and it seems that cancer tumors themselves may be expressing their own IGF-1 - thus driving overall IGF-I levels higher (not that high levels
caused the tumors)
While these articles are well above my level of bio chemistry knowledge
I often think of all of the professional bodybuilders taking massive amounts of pure growth hormone. I have not heard of any of them dying from cancer prematurely, and the GH doses they take are far more potent than what we get from an IGF-I secretagogue.
I have also seen at least four clinical trial studies about secretagogues, and new trials are pending, and no cancer reported anywhere.
My point is - I think the levels we are dealing with are not worth worrying about.