Baclofen and loss penis sensitivity

  1. Baclofen and loss penis sensitivity


    Hello all

    I posted many months ago on another forum about this problem but i could not find solution for my problem.

    I hope this issue will be solved.

    Three years ago i took a pills of baclofen 2x 50mg only twice in one week as a result i lost my penis sensitivity.

    I readed many reasearch about baclofen and gaba-b which is stimulated. with this product.
    Many specialist said me that my sensitivity can be restored after weeks of withdrawl. Unfortunately still have this problem unresolved

    By this problem i can not keep erection Many peoples which used baclofen having sex normally.
    I tested two weeks ago my hormones. I readed about this on this forum.

    Testosterone: 687,99 ng/dl
    Estradiol: 44,79 pg/ml

    Maybe this is normal estradiol levels in my body. I do not any results before use baclofen. It's Possible that baclofen can raise Estradiol?

    Please help me

    i'm 28 years male


  2. You could try a GABA B antagonist. It does the oppose of baclofen and *may* help by upregulating the receptors baclofen downregulates. Fasoracetam and homotaurine are considered safe and sold as nootropics.
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  3. estradiol response depends on where SHBG is
    I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.

  4. Actually very good idea to try nootropics as first line

    Dr B

  5. In terms of penis sensitivity try L-Histidine.

    It works 100%

    I had major issues when I was younger, and couldn't release with a partner. I took 3-5g for a few days, and then 1-3g and it made a huge difference.

    There is a thread somewhere, but I can't remember where. It's cheap, and effective.
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  6. Quote Originally Posted by chemiuser View Post
    You could try a GABA B antagonist. It does the oppose of baclofen and *may* help by upregulating the receptors baclofen downregulates. Fasoracetam and homotaurine are considered safe and sold as nootropics.
    What benefits do these provide, safe?

  7. They upregulate GABA-B receptors when taken regularly. Think of it like an antidote to phenibut or baclofen. Both studied in humans and considered safe. If baclofen caused his problem by downregulating GABA B receptors the only true way to fix it is to treat the underlying cause by upregulating the receptors.

  8. Antagonist of GABA-b receptor. Very odd that chemise knew that lol that was a good call

    Nootropics could be classified as mood and mind enhancing drugs, like any drug you have to use it correct to be safe

    Dr B

  9. Thanks for replies Taurine seems to be agonist not antagonist it's True?
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