I decided to do the private MD labs hormone panel as well as SHBG, and here is what I got:
What does the low FSH indicate?
LH 3.6 ( range 1.7-8.6 mIU/mL CB)
FSH 1.2 LOW (range 1.5-12.4 mIU/mL CB)
Sex Horm Binding Glob, Serum 43.4 (range 16.5-55.9 nmol/L CB)
Testosterone, Serum 620 ( range 348-1197 ng/dL CB)
Free T 14.2 pg/mL (range 9.3-26.5)
Estradiol 26.9 ( range 7.6-42.6 pg/mL CB)
I posted in another thread, but didn't really get a response. Please advise (symptoms include low libido/performance issues, anxiety, fatigue).
The urologist that I saw 2 weeks ago didn't even know what SHBG was and ordered "total estrogen" instead of E2, why is why I ordered the private md lab test. What should I tell an endo? I've seen 2 endos previously for my symptoms (low libido/performance issues, fatigue) and they dismissed it as "in my head" without even investigating. I'm definitely concerned about the LSH and high SHBG. The research I've been doing is indicating that it could be a potential issue with my pituitary? Although having low LSH without accompanying low LH seems to be rare. I'm 27, I workout 5 days a week and eat relatively healthy. Are there any other blood tests I should get?
My prolactin was measured in 2012: Value 5.8 (range 1.6-18.8 ng/mL)
Also my testosterone took a big dip in 2012:
2011 total T 978 (range 280-1000)
2012 total T 568 (range 280-1000_
2013 total T 620 (range 348-1197)
The private MD labs did include a CBC (this was taken 2 days ago):
CBC With Differential/Platelet
WBC 4.9 3.4-10.8 x10E3/uL CB
RBC 4.48 4.14-5.80 x10E6/uL CB
Hemoglobin 13.2 12.6-17.7 g/dL CB
Hematocrit 39.1 37.5-51.0 % CB
MCV 87 79-97 fL CB
MCH 29.5 26.6-33.0 pg CB
MCHC 33.8 31.5-35.7 g/dL CB
RDW 14.1 12.3-15.4 % CB
Platelets 241 155-379 x10E3/uL CB
Neutrophils 57 40-74 % CB
Lymphs 33 14-46 % CB
Monocytes 8 4-12 % CB
Eos 2 0-5 % CB
Basos 0 0-3 % CB
Neutrophils (Absolute) 2.8 1.4-7.0 x10E3/uL CB
Lymphs (Absolute) 1.6 0.7-3.1 x10E3/uL CB
Monocytes(Absolute) 0.4 0.1-0.9 x10E3/uL CB
Eos (Absolute) 0.1 0.0-0.4 x10E3/uL CB
Baso (Absolute) 0.0 0.0-0.2 x10E3/uL CB
Immature Granulocytes 0 0-2 % CB
Immature Grans (Abs) 0.0 0.0-0.1 x10E3/uL CB
Comp. Metabolic Panel (14)
Glucose, Serum 90 65-99 mg/dL CB
BUN 12 6-20 mg/dL CB
Creatinine, Serum 0.84 0.76-1.27 mg/dL CB
eGFR If NonAfricn Am 120 >59 mL/min/1.73 CB
eGFR If Africn Am 139 >59 mL/min/1.73 CB
BUN/Creatinine Ratio 14 8-19 CB
Sodium, Serum 141 134-144 mmol/L CB
Potassium, Serum 4.4 3.5-5.2 mmol/L CB
Chloride, Serum 102 97-108 mmol/L CB
Carbon Dioxide, Total 25 19-28 mmol/L CB
Calcium, Serum 9.5 8.7-10.2 mg/dL CB
Protein, Total, Serum 7.1 6.0-8.5 g/dL CB
Albumin, Serum 4.6 3.5-5.5 g/dL CB
Globulin, Total 2.5 1.5-4.5 g/dL CB
A/G Ratio 1.8 1.1-2.5 CB
Bilirubin, Total 0.5 0.0-1.2 mg/dL CB
Alkaline Phosphatase, S 60 39-117 IU/L CB
AST (SGOT) 18 0-40 IU/L CB
ALT (SGPT) 17 0-44 IU/L CB
Testosterone, Serum 620 348-1197 ng/dL CB
Luteinizing Hormone(LH), S
LH 3.6 1.7-8.6 mIU/mL CB
FSH 1.2 LOW 1.5-12.4 mIU/mL CB
Estradiol 26.9 7.6-42.6 pg/mL CB
Sex Horm Binding Glob, Serum
Sex Horm Binding Glob, Serum 43.4 16.5-55.9 nmol/L CB
I appreciate any help on this!
What would cause high SHBG? Also, has anyone used stinging nettle successfully?
BTW, for anyone looking to get their own labs, my experience with private MD labs was very good. It was pretty hassle-free and not that expensive. I'm planning to get more labs (progresterone, DHEA, cortisol, DHT, TSH, T3-T4) eventually.
Yes, I have used a rather strong stinging nettle extract, but I have not done before and after bloods.
BTW - you want stinging nettle root, not stinging nettle leaf. They are both good, but for different things. For SHBG - you want to use the root extract. For allergies - you would want to use the leaf.
Here is some additional information I "lifted" from a post in "All Things Male":
SHBG is made in the liver in response to levels of many hormones:
1. Increasing Testosterone reduces SHBG
2. Increasing DHT lowers SHBG
3. Increasing DHEA lowers SHBG
4. Increasing Growth Hormone lowers SHBG
5. Increasing Insulin lowers SHBG
6. Increasing Estrogen increases SHBG
7. Increasing Thyroid Hormone increases SHBG
The SHBG level is determine by the balance of the hormone levels.
Given one's assumed goals in TRT (high libido, good energy, etc.), it may be difficult to increase SHBG without causing problems since SHBG is determine by a balance of hormones.
For example, having high Testosterone and high DHEA is not a situation where SHBG is going to be high without corresponding problems with estrogen or thyroid.
If anything, SHBG should be most often viewed as an indicator of a problem that needs to be solved - rather than as a problem itself.
For example, SHBG is most commonly an indicator of high insulin levels - i.e. insulin resistance or diabetes. It would be then far more important to address insulin resistance or diabetes in treatment than to focus on SHBG.
If low thyroid is a factor in low SHBG, addressing hypothyroidism is far more important.
If low estradiol is a factor in low SHBG, addressing this is more important.
If the low SHBG itself is a problem because it causes large swings in hormone levels, then working around this by achieving more stable hormone levels is indicated.
Does anyone know what kind of doctor would actually be familiar with FSH and why it might be low?