DHEA supplementing while on TRT
- 09-06-2011, 11:32 AM
DHEA supplementing while on TRT
I'd like to get some input from the anti aging gurus over here about how you all feel about the importance of using a DHEA product if you are on trt?
With the recent release of our RS transaderm, which is a topical DHEA solution and enjoying great success far, I have heard from more than a few guys who like to use a topical dhea as part of their trt to help hormonal balance.
It would seem to me to be a great idea and addition, especially if you are not running hcg.
ambulldog has been running it in his trt after switching from the dermacrine (transaderm is the same old dermacrine formula, with a hugely improved carrier and twice as many servings) and is going to be doing an unbiased comparison review of the two for us after a month of continuous use.
You can find that thread here:
my dermacrine vs transderm review is right around the corner
So any input from the anti aging crowd over here? Matrix, dragonrider, Easy...?
- 09-06-2011, 11:49 AM
I said screw transdermal and just inject it
Note: you will probably see a new trend in HRT coming into play as I have been using my body as a human lab rat for past few years before recommending it to the Dr's patients I consult with. I have been researching this for a few months and working with a compounding pharmacist on a injectable DHEA which I have been using for the past 3-4 weeks. Results will be posted in a few weeks once I clear issues with billing from the idiots from the labs. I just kocktail it in with testosterone 2 times a week no slapping cream on me 3 times a day. Its easy and has given me benefits orals have not with out the e2 kick up. This is what I was looking for to bring my levels up to 300-350 at my trough. I will also get DHEA 24 hour urine as well in the mid phase. I am curious as this may start a new trend in HRT since it is much more user friendly.
Benefits so far
1. No rise in e2
2. More vivid dreams
3. better resistance to stress
4. Better refractory time - can perform 2 -3 times a day vs once
5. World seems more bright and colorful
6. Morning wood like clock work
7. excessive erection during the day
8. Thinking about sex more often then usual. (dopagenic effect)
9. Waking up feeling more fresh in the morning - no more coffee needed.
09-06-2011, 01:34 PM
is it an esterified DHEA? and what sort of dosage?
I've thought about dhea, pregnenelone and direct DHT as additions to the injected testosterone of TRT.
09-06-2011, 08:19 PM
I am subbed for more discussion and input from everyone on their thoughts about this.
Recoverbro Elite"This is what we've been working on"
09-06-2011, 08:54 PM
09-06-2011, 09:14 PM
Here is a link for you guys to read:
It notes the importance of DHEA in general, explains how it works, and maybe about 2/3 of the way through the article there is a section on its important role in testosterone replacement therapy.
09-07-2011, 02:45 AM
09-07-2011, 07:05 AM
This sounds awesome (injectable esterified DHEA). Now all I need is a clinic to provide esterified DHT, mixed with my test, then I will be free of creams for good. If compounding pharmacies could offer tailored mixes like this for patients, that would be super amazing...
For now I've ordered more of PP's dermacrine.. was happy to see it come back
09-07-2011, 07:27 AM
09-07-2011, 07:35 AM
DHEA has a short half life and most circulates as the bio-active sulphate. One should not test DHEA levels, test DHEA-S. So your half life concern is not really an issue at all.
DHEA release is pulsatile. This makes lab results sort of useless. DHEA-S is the proxy.
Supplemental DHEA is most useful when DHEA level are decreasing with age, which starts in the early 30's. When DHEA is very low, DHEA-->T can be rate limited and supplemental DHEA can sometimes allow for improved testosterone levels. But high testosterone levels will never happen. There is some DHEA-->T in the adrenals that in not controlled by the HPTA feedback loop. That contribution is small in terms of male requirements, but for some female taking DHEA can significantly increase T levels, as female levels are so low compared to males.
Young men taking DHEA is stupid as they have very high natural DHEA levels. For younger males DHEA may have some negative effects, which can be permanent.
A few males in the TRT group report that DHEA drives up estrogen and can have some other negative effects, which might all be estrogen related. However, such problems seem to be quite rare.
found ^^^^ this on another forum i frequent
09-07-2011, 09:43 AM
dhea impact on e2 is driven by mode of delivery. Oral can increase e2 because of the first pass of the liver. Td application will.reduce it affect.of down stream metabolism. Injection is just a straight shot avoiding majority of impact on liver. Been feeling sexually like a teenager again better then being on t, hcg and ai.
09-07-2011, 10:29 AM
09-07-2011, 11:05 AM
It depends on what factors are involved with the elevation of e2.
Could moving from an oral to TD reduce e2? possible due to how it is metabolized by the body.
If the e2 is already elevated and no DHEA is taken then no it would not.
I work on reducing people's e2 by manipulating hormone and detoxification pathways to help manage the estrogen load in the body.
09-07-2011, 12:24 PM
09-07-2011, 01:04 PM
09-07-2011, 01:16 PM
09-07-2011, 01:39 PM
09-07-2011, 01:45 PM
09-07-2011, 09:45 PM
haha... thanks Matrix .... so far ... pretty good and stable. Will get bw done in about 1-2 weeks and then see what needs tweaking.
09-07-2011, 10:04 PM
I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
09-07-2011, 10:39 PM
I agree.... the things that I can control I will put utmost effort to doing things right .... as far as the rest... new territory for me ... and your not in Illinois
09-08-2011, 08:18 AM
09-08-2011, 11:38 AM
09-08-2011, 04:16 PM
DragonRider is a fictional character and does not promote the use of anabolic steroids without a doctor's prescription. The information I share is my opinion based upon my personal experiences only and should not be construed as medical advice.
09-08-2011, 05:45 PM
LG Sciences Board Rep
These statements have not been evaluated by the FDA, do not constitute medical advice, and are not official or authorized comments by LG Sciences, LLC.
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