Is there a good way to lower DHT?

[nycjimi]

I have low test but high DHT. Adding test skyrockets my DHT and hair loss and acne ensue.

So what to do?

[punxweb]

How are you taking your test? Transdermal or shot? For some, transdermals will increase DHT. For those that it happens to typically switch to shots.

[nycjimi]

Test injection. Twice a week. 25 mg per shot.

Serum test is 450 on a range of 305-800
Serum DHT is 105 on a range of 25- 75

[punxweb]

Thats a pretty low dose of test to see a large increase of DHT. I know some on this forum suggest having DHT slightly above the reference range. I do not know how far above though. I have heard that saw palmetto helps lower DHT but I have no experience with it. What was your DHT before starting HRT?

[nycjimi]

My pre HRT numbers were:
Test 290 350-800
DHT 70 35-75

[punxweb]

Could look into finasteride and dutasteride if the DHT gets out of hand. Wouldn't be my first choice. I am sure some others on here will pipe in soon. You were in the upper range when starting HRT and the small amount you did brought you out of range. Thats strange man. Hope others with more experince with this will chime in.

[Philec48]

Beware using those drugs! Want to shut down your libido? Permanently? It has happened to some men. Punxweb, glad it's not your first choice. Shouldn't even be 100th choice.

Listen, DHT of 105 in a range of 25-75 is not lethal. It should be NOTHING to worry about unless there are side effects.

If that side effect is difficulty peeing due to swelling of the prostate, then for crying out loud take nettle root and saw palmetto together. This is just as effective as dutasteride according to some studies, and without the effect of killing libido.

Let the doctors push these drugs, not us!

[corsaking]

get a psa check before embarking on anything

[punxweb]

Believe me phil, I was not saying these drugs were the best option. I was only stating that he had options.

[WORKOUT COACH]

I have low test but high DHT. Adding test skyrockets my DHT and hair loss and acne ensue.

So what to do?

Endocr Regul. 2010 Jan;44(1):3-8.

Changes of metabolic profile in men treated for androgenetic alopecia with 1 mg finasteride.
Duskova M, Hill M, Starka L.

Objective. Androgenetic alopecia is recognized as a risk factor for cardiovascular diseases, glucose metabolism disorders, and benign prostate hyperplasia and/or carcinoma. Finasteride, used for treatment of androgenetic alopecia at a dose of 1mg/day, is an effective inhibitor of type II 5alpha-reductase, the enzyme responsible for the reduction of testosterone to dihydrotestosterone. Recent studies reported that dihydrotestosterone, among other activities, might play some role in visceral fat metabolism. It thus seemed reasonable to examine whether finasteride treatment of androgenetic alopecia ameliorates some features of metabolic syndrome frequently seen associated with this condition. <br />Methods. We examined 12 men with premature balding (defined as frontoparietal and vertex hair loss before age 30 with alopecia defined as grade 3 vertex or more on the Norwood-modified Hamilton alopecia classification). Hormonal levels and metabolic parameters were determined and insulin tolerance tests performed for all individuals. Finasteride (1 mg/day) was administrated for 12 months. The hormonal profile and lipid spectrum were monitored after 4, 8 and 12 months of treatment and insulin tolerance tests were repeated after 12 months of the treatment. <br />Results. After treatment with finasteride the expected changes in the steroid spectrum were seen, namely a decrease in dihydrotestosterone and increase in testosterone, androstenedione and free testosterone index. We observed an initial increase in total cholesterol and HDL- and LDL-cholesterol, which stabilized with prolonged treatment. We founded a significant decrease in glycated hemoglobin HbA1c and insulin resistance measured using rate constant for plasma glucose disappearance (kITT) showed only a borderline decrease.<br />Conclusions. Finasteride is an efficient 5alpha-reductase inhibitor even at low doses of 1mg/day. In men treated with this dose for 12 months, we observed mild differences in metabolic profile with slight amelioration of glucose metabolism regulation. Keywords: Finasteride - Androgenetic alopecia - Androgens - Lipids - Insulin sensitivity - Metabolic disorders.

[liquid]

Myodrol: New Test Booster From Axis

It is a new test booster made by Axis Labs.
I have read a study where it shows the ingredients increase test serum, and lowers dht.

[celc5]

Myodrol: New Test Booster From Axis

It is a new test booster made by Axis Labs.
I have read a study where it shows the ingredients increase test serum, and lowers dht.

Thanks for posting the link

I personally wouldn't expect any negative response to myodrol in this particular scenario. At the same time, we don't have any reports that say it will help yet either. Theoretically, good idea. More to come once it's in the hands of the people

Just another side note: OP, what is your response to formestane? It's absolutely proven to reduce DHT. I wish I had personal bloodwork to support my theory, but I suspect that it control DHT at low doses such as 20mg TD 2-3x/day. Just something to consider.

[Knowbull]

The sterides really are bad. A guy might want to consider an expensive regimen of; Resveratrol, RLA/RDHLA/Tocotrienol combination, L-Carnitine, Zinc and Beta-sitosterol. Ive never used Formestane, but reviews are good. JMO

[liquid]

Thanks for posting the link

I personally wouldn't expect any negative response to myodrol in this particular scenario. At the same time, we don't have any reports that say it will help yet either. Theoretically, good idea. More to come once it's in the hands of the people

Just another side note: OP, what is your response to formestane? It's absolutely proven to reduce DHT. I wish I had personal bloodwork to support my theory, but I suspect that it control DHT at low doses such as 20mg TD 2-3x/day. Just something to consider.

My mistake, I should mention that the study that was conduct was not Myodrol. But a different supplement but contains similar ingredients.

[spinn]

Did I misunderstand this policy Posting Referral and Source Information

[celc5]

My mistake, I should mention that the study that was conduct was not Myodrol. But a different supplement but contains similar ingredients.

You're post was appropriate in terms of DHT control and it was the same ingredients as far as I could tell

I was more referring to the HRT scenario. It's tough for me to suggest results when we really haven't had much feedback yet. If, in the near future, we end up with feedback from someone on HRT who reports decreased DHT-esque symptoms, THEN we'll be recommending it for this scenario.

Did I misunderstand this policy Posting Referral and Source Information

Spin,
as far as I can tell the study posted by Workout Coach was appropriate. So was the link posted by poison (it links back to another AM thread).

Unless you had a post deleted that I missed, I do think you're misunderstanding the policy

[WORKOUT COACH]

You're post was appropriate in terms of DHT control and it was the same ingredients as far as I could tell

I was more referring to the HRT scenario. It's tough for me to suggest results when we really haven't had much feedback yet. If, in the near future, we end up with feedback from someone on HRT who reports decreased DHT-esque symptoms, THEN we'll be recommending it for this scenario.



Spin,
as far as I can tell the study posted by Workout Coach was appropriate. So was the link posted by poison (it links back to another AM thread).

Unless you had a post deleted that I missed, I do think you're misunderstanding the policy

Did I do anything wrong? I only posted a study from medline that was relavent to the question. I apologize if I did.

[corsaking]

Myodrol: New Test Booster From Axis

It is a new test booster made by Axis Labs.
I have read a study where it shows the ingredients increase test serum, and lowers dht.

the main ingredient is SAW PALMETTO=save your money and buy from a health food shop at a lower price. it needs to be standardised and the ideal dosage is 320 mg per day -taken once or 2 x 160mg

[celc5]

the main ingredient is SAW PALMETTO=save your money and buy from a health food shop at a lower price. it needs to be standardised and the ideal dosage is 320 mg per day -taken once or 2 x 160mg

Well, let's not judge it till we try it. An argument could be made that our Hemodraulix product is 'JUST' a pump product. But once people try it, they usually drop the "just another pump product" stigma and buy another bottle.

Also, my impression is that the main ingredient does not appear to be saw palmetto. It looks to be the astaxanthin.

You are certainly entitled to your opinion. However, you've made your statements as if they are concrete facts.

[spinn]

the main ingredient is SAW PALMETTO=save your money and buy from a health food shop at a lower price. it needs to be standardised and the ideal dosage is 320 mg per day -taken once or 2 x 160mg

Are you sure it isnt SAW DUST?