I've been having some symptoms of high estrogen lately. I got my endocrinologist, who is treating me for a thyroid condition, to run an estradiol test. The result was 18 pg/ml (<56). He said I was fine and to stop worrying. I ignored him and took my results to a local family doctor that is obsessed with fitness (he is in better shape than me and thirty years older). I showed him my E2 test result, and he told me that the test was garbage since it wasn't a sensitive assay, and it listed reference values for both men and women (I guess implying not gender specific enough). He believes that my estrogen levels are high, and that a sensitive E2 test will prove it. He wants me to have another blood test on Monday using a sensitive assay.
I'm confused then. I thought the whole point of a sensitive assay was that it actually listed a given number instead of just saying "< some number". If that's the case, then my E2 test was fine. Do the sensitive tests actually give a more accurate representation of the E2 levels in men? Or is my doc just misinformed?
People on various forums have asked this question before, but it seems that a good answer is never given.