Originally Posted by henry5th - Total Flex Blog
Function:
This is a prohormone to the veterinary drug and black-market bodybuilding steroid trenbolone. Unlike previous ?tren? prohormones, this one actually converts in the body to trenbolone. Previous ?tren? PHs converted to the structurally similar ? but markedly weaker ? steroid dienolone.
Structure:
This prohormone has the same three conjugated double bonds as trenbolone, and differs from it only in that this hormone has a 17-ketone, where trenbolone has a 17b-hydroxy function. In the body this ketone will be readily hydrolysed by 17b-hydroxysteroid dehydrogenase type 5 (17b-HSD5) into the active form, trenbolone.
Effects:
Conversion to trenbolone should mean that effects should be very similar to the injectable form ? with the exception of the famed ?tren cough?. Whatever the explanation for ?tren cough? (and many have been suggested), since it?s a reaction to the sudden parenteral introduction of some compound directly into the body, it?s highly unlikely that any orally administered compound will have the same effect.
Trenbolone is one of the strongest injectable steroids on the market, so effects experienced from Trenabol can be expected to be largely the same ? strength and size increases, accelerated fat loss, and enhanced vascularity.
Side Effects:
Blood pressure is likely to be dose-dependently elevated to a significant degree, cholesterol levels and liver function markers are likely to be adversely affected, though to what extent remains to be seen. Commonly reported trenbolone sides include night-sweats, mood swings, androgenic hair loss and/or growth, temporarily increased or reduced libido, as well as the suppression of endogenous testosterone production, and it would be sensible to assume that these may also result from use of Trenabol.
Detection Limits:
An anti-doping study from 1996 found that orally administered trenbolone was detectable by mass spectrometry for two to four days after a single administration, unlike injectable trenbolone, which is detectable for much longer. [10] The detection of trenbolone after administration of Trenabol is likely to follow similar lines, though detection methods may have improved since then. Athletes subjected to doping tests should of course avoid this and all other prohibited performance-enhancing products altogether.
References:
[1] Steroids 74 (2009) 172?197
[2] Acta Endocrinologica, Vol 110, 1 Suppla, S129-S130
[3] J Steroid Biochem 1979;13:45?59.
[4] Toxicol Sci. 2002;70:202?211.
[5] Xenobiotica. 1981 Jul;11(7):489-500.
[6] Biol. Mass Spectrom. 20 (1991) 459?466.
[7] Recent advances in doping analysis (2). (1995) 269-274.
[8] Anal Chim Acta. 2009 Apr 1;637(1-2):92-100.
[9] PHF Forum ? 17b-methoxy-trienosterone
[10] Recent advances in doping analysis (3). (1996) 83-94.