[datBtrue]

Thread Index: [ POST #1 ]

Originally Posted by pumbertot

...
True I don't have much time to be bored with a 5 day old baby in the house!

Congratulations to you and your wife. That really is awesome news!

Wow time flies...I thought it was just yesterday that you said your wife was 3 weeks due but its been a whole month. Glad everything went well.

[wophood]

Hey Dat, I've been running ghrp+cjc at the same approximate dosage scheme as papa (was running Pum's rocket fuel for the first couple weeks but backed off of the ghrp a bit). I have incorporated igf into this post-op cocktail as well with a slightly irregular schedule. It's been exactly four weeks, at six I was going to post my results & exact protocol. Would you like me to post them here, or should I start a separate thread?

This is a shout out for Pumbertot. He has helped me a great deal... Didn't forget ya man! Congrats on the new member of your family, too!

[pumbertot]

Originally Posted by wophood

Hey Dat, I've been running ghrp+cjc at the same approximate dosage scheme as papa (was running Pum's rocket fuel for the first couple weeks but backed off of the ghrp a bit). I have incorporated igf into this post-op cocktail as well with a slightly irregular schedule. It's been exactly four weeks, at six I was going to post my results & exact protocol. Would you like me to post them here, or should I start a separate thread?

This is a shout out for Pumbertot. He has helped me a great deal... Didn't forget ya man! Congrats on the new member of your family, too!

Thanks bro. And thanks dat.

[datBtrue]

Originally Posted by wophood

Hey Dat, I've been running ghrp+cjc at the same approximate dosage scheme as papa (was running Pum's rocket fuel for the first couple weeks but backed off of the ghrp a bit). I have incorporated igf into this post-op cocktail as well with a slightly irregular schedule. It's been exactly four weeks, at six I was going to post my results & exact protocol. Would you like me to post them here, or should I start a separate thread?

This is a shout out for Pumbertot. He has helped me a great deal... Didn't forget ya man! Congrats on the new member of your family, too!

Yes please post up here. I have been interested in both doses higher than 2.1mgs/week (having now explored this and lower levels myself) and also how GH & IGF-1 behave together primarily since Bobaslaw referred me to the study: Physical and Functional Interaction of Growth Hormone and Insulin-Like Growth Factor-I Signaling Elements, YAO HUANG, Mol Endocrinol, June 2004, 18(6):1471–1485

I have noted studies like, Enhancement of the Anabolic Effects of Growth Hormone and Insulin-like Growth Factor I by Use of Both Agents Simultaneously, Stuart R. Kupfer, J. Clin. Invest. 1993. 91:391-396. with such conclusions as "combination of GH and IGFI treatment is substantially more anabolic than either IGF-I or GH alone." This conclusion is tempered by the fact that the study participants were calorically restricted and in a catabolic state and the effect that was measured was "nitrogen retention". So it probably has limited relevance to us because the participants were in hyperglycemic states to begin with and these hormones were used to prevent loss in such states.

Not withstanding these limitations I am very interested in your results. Thanks for making the offer. Much obliged.

[likkayouth]

After reading the following studies:

Acipimox, a nicotinic acid analog, stimulates grow...[J Pediatr Endocrinol Metab. 2000 Sep-Oct] - PubMed Result
Growth hormone, cortisol, and glucagon concentrati...[J Clin Endocrinol Metab. 1983] - PubMed Result
Growth hormone, glucagon, and insulin response to ...[J Clin Endocrinol Metab. 1977] - PubMed Result
Influence of ketone body infusion on plasma growth...[J Clin Endocrinol Metab. 1983] - PubMed Result

would you use niacin to enhance the effect of the peptides, and if you do, how would you go about it?

[datBtrue]

Originally Posted by likkayouth

After reading the following studies:
...
would you use niacin to enhance the effect of the peptides, and if you do, how would you go about it?

You tell me.

To what extent does acipimox differ from niacin? Is it okay for us to take a study using a niacin derivative and attribute those findings to niacin?

The first study tells us that Acipimox elicited an additive effect to GHRH and or GHRP-6.

The added effect was small (compared to GHRH+GHRP-6) but significant...say 7 mcg/l and illicited a GH peak occuring 180 minutes post administration.

So if you assume GHRH+GHRP-6 illicits a GH peak 30 minutes post injection then you would take the Acipimox 150 minutes prior to taking the GHRH/GHRP-6.

If you are using it as a standalone for example pre-bed take it an hour and a half before bed.

The other 3 studies are 25+ years old and I think not directly on point.

But you have read all of these studies so please elaborate and give us your thoughts.

[likkayouth]

Originally Posted by datBtrue

But you have read all of these studies so please elaborate and give us your thoughts.

I really only have access to the abstracts, so I am drawing ideas/conclusions from them.
I was mainly worried by you saying that "Fatty acids inhibit GH release even more than carbs." and the fact that it's hard for me to control my fat intake where I'm at right now. From those studies I concluded that acipimox and niacin lower free fatty acids levels. I was thinking about taking about 500 mg of niacin with my last meal before bed, hoping it would reduce free fatty acids so they don't inhibit the effect of the pre-bed cjc-1295 shot.

I was also hoping some one would reply with "No, I wouldn't do that, because niacin has this and that negative effect, which would interfere with this and that".

[datBtrue]

Originally Posted by likkayouth

I really only have access to the abstracts, so I am drawing ideas/conclusions from them.
I was mainly worried by you saying that "Fatty acids inhibit GH release even more than carbs." and the fact that it's hard for me to control my fat intake where I'm at right now. From those studies I concluded that acipimox and niacin lower free fatty acids levels. I was thinking about taking about 500 mg of niacin with my last meal before bed, hoping it would reduce free fatty acids so they don't inhibit the effect of the pre-bed cjc-1295 shot.

I was also hoping some one would reply with "No, I wouldn't do that, because niacin has this and that negative effect, which would interfere with this and that".

I'm inclined to say it looks like it will be of extra benefit. Niacin is great...so unless someone else has something negative to say I'd say enjoy the flush.

By-the-way it is wise to try to control those fats pre-bed. I got deeper sleep from these peptides when I stopped my fats a few hours pre-bed.

[wophood]

Originally Posted by datBtrue

By-the-way it is wise to try to control those fats pre-bed. I got deeper sleep from these peptides when I stopped my fats a few hours pre-bed.

I agree 100%. I wait a minimum of three hours after consuming any sort of fatty substance before hitting the hay. Ever since I began my cycle with these particular peptides (ghrp+cjc), I've been going comatose at night & having some quite vivid dreams.

[datBtrue]

Originally Posted by wophood

I agree 100%. I wait a minimum of three hours after consuming any sort of fatty substance before hitting the hay. Ever since I began my cycle with these particular peptides (ghrp+cjc), I've been going comatose at night & having some quite vivid dreams.

You want to have even deeper sleep add some MT-II an hour before bed.

[MyRevolution]

I would assume that since niacin inhibits FFA release, which is part of the negative feedback loop, it (might) improve GH release. The question is whether you really want to inhibit FFA release...

[wophood]

Originally Posted by datBtrue

You want to have even deeper sleep add some MT-II an hour before bed.

Might look into it, sleeping never has been my forte. Lol, but of course the night I write a message saying that I've been sleeping well (last night), I couldn't breathe without waking myself up! Ugh, I should have knocked on wood...

[papapumpsd]

Originally Posted by wophood

Might look into it, sleeping never has been my forte. Lol, but of course the night I write a message saying that I've been sleeping well (last night), I couldn't breathe without waking myself up! Ugh, I should have knocked on wood...

I haven't been sleeping so well since CJC/GHRP. I wake up a lot...feel hot and dry. My girlfriend clings onto me like a lil monkey at night, so that def. doesn't help. I had the window open last night (usually do) and this F*CKING train kept blowing its horn for like 30 min. If I had a rifle I prob. would have used the damn thing.

I'm hoping I start sleeping better. I wake up exhausted and just zonked out. I wake up quickly though and usually don't have any issues throughout the day. I do drink coffee though.

[futurepilot]

Originally Posted by papapumpsd

I wake up quickly though and usually don't have any issues throughout the day.

I've noticed that i sleep alot less: quality has improved, but quantity has been reduced. Which is great for me being in school and everything.

[wophood]

Quick question, & I'm asking because this is pretty specific and hard to research so I figured someone here might have the jump on it. I recently got a gash, and didn't think it was a big deal. Long story short I wound up having to go to the doc's AGAIN, & now I have to be on two antibiotics cause it's infected. One is good ol' cephalexin, the other is smz/tmp?... the generic for bactrim.

Is there anything I should/need to know about these two antibiotics that could possibly inhibit the efficiency of my peptides? Neither has to be taken with food, so it won't change my diet in any way, meaning my injection schedule throughout the day can remain the way it is.