Dat's - Growth Hormone Releasing Hormone (GHRH) & Growth Hormone Secreatogues (GHS)

**DAdams91982** · 06-16-2008, 04:08 AM

Hey... I have access to a few full blown databases, and can pull most full texts. SO if you all need something, just let me know.

Then I can be your project afterwards.

Adams

TripDog · 06-16-2008, 04:19 AM

Wow, thats a crazy story man. I use a moderate dose of na-rala before my ghrp-6 shots to make sure blood sugar is low, but I never had anything like that happen.

datBtrue · 06-16-2008, 06:25 AM

datBtrue · 06-16-2008, 06:30 AM

papapumpsd · 06-16-2008, 08:53 AM

Quote:

Originally Posted by datBtrue

Thanks bro. I appreciate it. I have access to most databases and most full texts. I have about 250 studies/reviews on this topic on my computer at the moment categorized under various headings.

Every once in a while I'll come across a chemistry paper I'd like but don't have the access to so I may take you up on your offer now and and again.

Thanks again.

Ever consider zipping these studies up and putting them out on a torrent? I'd like to DL them!

Bobaslaw · 06-16-2008, 11:10 AM

Holy Googly Moogly Dat!

Please be careful bro! Thats one of those scarry slin experiences for sure. Good thing you do the right thing and carry glucose tabs on you at all times. You just never know...

EasyEJL · 06-16-2008, 12:55 PM

I need to read thru this thoroughly later, but i'm at work right now

datBtrue · 06-17-2008, 03:29 AM

datBtrue · 06-17-2008, 03:30 AM

datBtrue · 06-17-2008, 03:31 AM

datBtrue · 06-17-2008, 03:31 AM

Bobaslaw · 06-17-2008, 10:23 AM

Quote:

Originally Posted by datBtrue

I believe I found a study that allows us to understand what happened in my little experiment. Keep in mind that the presence of exogenically administered insulin has the effect of blocking the GH-Receptor (like the drug administered in the study below). I was in a non-fasted state with food in my stomach (same as the study)...exogenic insulin was present and then GHRP-6 was administered (in a dose identical to the study below). My blood sugar probably dropped rapidly because my own indigenous insulin production rapidly increased (as was the case in the study below).

This also explains why I felt my defined abdominal section was a bit washed out following two days of lipogenesis as described below.

By-the-way I repeated the insulin protocol minus the second dose of GHRP-6 tonight w/o incident.

Very Interesting Dat as I also looked for answers to this and did not come across this study.
However, I am not certain as of yet that this applies, due to some conclusions I have not seen support of...

I have not seen any info regarding insulin being a GHR antagonist which you use to compare to the GHS antagonist used to induce the effects in the study you posted.
Actually the studies I saw on GHRP-6 and Ghrelin showed that there were no changes in insulin with administration of GHRP-6 under normal circumstances (no GHR antagonist used).

Obviously GH does impact insulin resistance as this is a documented effect of GH. So the eventual hyperinsulinemic levels the body produces are countered by a rise in tissue resistance (downregulation of the IR?)to the high insulin levels which actually leads to a state of hyperglycemia (and diabetes) and not hypo. Not sure the short term conditions and symptoms before the long term conditions develop, however.

The only info on Insulin that i have found to date is that is actually upragulates the GHR.

http://cat.inist.fr/?aModele=afficheN&cpsidt=841406

I have not, however, eliminated the possibility that the GHR is upregulated by Insulin because it does in fact antagonise the receptor. Such pathways are shown with may antagonist/agonist effects on up and downregulation of respective receptor types.

I am very interested for any more info you may have on this, Dat.

Take Care.

datBtrue · 06-18-2008, 01:56 AM