METFORMIN AND ITS BENEFITS FOR GHRP THERAPY
- 09-05-2010, 01:44 PM
METFORMIN AND ITS BENEFITS FOR GHRP THERAPY
I FOUND SOME METFORMIN AND WAS WONDERING THE BEST WAY(TIMES,DOSAGES,EFFECTIVENES S)TO USE..IF IM RIGHT I BELIEVE IT IS ORAL INSULIN.I AM PLANNING ON RUNNING A GHRP/CJC-1295 CYCLE SOON AND WOULD LIKE SOME ADVICE ON THE BEST WAY TO UTILIZE THIS DRUG WITH MY UPCOMING GHRP CYCLE.
- 09-05-2010, 05:08 PM
You found some Metformin?
Sorry bro, you are mistaken, Metformin is not oral insulin. It is a drug that improves insulin sensitivity and slows down hepatic glucose release.
- 09-05-2010, 06:00 PM
09-05-2010, 06:20 PM
It is quite inexpensive. Regardless, not really convinced of its benefits for non-diabetics.
09-05-2010, 11:19 PM
09-07-2010, 09:59 AM
Metformin has its uses for non diabetics. Its not something you're going to "feel." Metformin is a glucose disposal agent. It takes stress off of the pancreas by decreasing the neccessary amount of insulin to lower blood sugar. It decreases glucose output by the liver, and blunts the spike in insulin from carbohydrate intake. It is used for the same purpose in non diabetics as diabetics. Lower blood glucose without the spike in insulin.
09-07-2010, 03:54 PM
09-07-2010, 04:03 PM
Are you claming that Anabolic pump, p-slin, recompadrol, glycobol, etc,etc. are all non beneficial in non-diabetics?
This really isn't even debatable; Metformin HCL is a clinically proven and FDA approved effective GDA... how many of the popular GDAs on the market today can make that kind of claim?
09-07-2010, 06:16 PM
A uniform reduction in insulin sensitivity in non-diabetic individuals is not a benefit because, if say, 100g of carbs are ingested, then 100g will still be taken up by the same cells. If you are not exceeding the capacity of your insulin function then there is no advantage to increasing your sensitivity to 'supraphysiological levels' because baseline blood glucose levels are non-zero.
Like all medications, Metformin also has its downsides. Even though most descriptions say there is little risk of hypoglycemia, IMO this is relative to taking too much insulin or 'stronger' oral treatments. I was on Metformin for about 2 years and I found that it could lower my blood glucose to about 20% below baseline with low-moderate activity. This is enough to up-regulate catabolism.
In short, I don't think there are enough pros for non-diabetics.
09-07-2010, 06:21 PM
09-07-2010, 06:42 PM
09-07-2010, 06:50 PM
Haha, gotta love language. I have no extracted publications from the annals of applied science to support these claims, but I can feel it, and its obvious to me that the proven benefits and method of action seen in diabetics can easily be carried over.
09-07-2010, 06:54 PM
09-07-2010, 07:17 PM
You are right though that the medical community does use the term pre-diabetic to specify those at early stage.
09-08-2010, 10:50 AM
My only point is... is metformin a useful tool for:
1. A diabetic - YES
2. A bodybuilder - YES
3. Average non diabetic person - NO
We are speaking about athletes and bodybuilders in this forum, not your average everyday person. So in short, yes to a bodybuilder metformin and other GDAs do prove useful for specific situational use. This doesn't mean that it's alright or good to use all the time indiscriminately.
09-08-2010, 11:26 AM
09-08-2010, 11:34 AM
09-08-2010, 08:15 PM
All in all, its not oral insulin.
09-08-2010, 08:18 PM
09-08-2010, 09:21 PM
09-09-2010, 03:10 PM
09-10-2010, 08:13 AM
i was told its hard on your kidneys, by a guy who is waiting for a kidney transplant.
09-13-2010, 11:48 AM
Metformin is beneficial to non-diabetics, and you don't have to be a BB either. As said already, it improves BG, Reduces the amount of insulin needed, and eases production of liver glucose. Metformin can be used as an adjunct to a fat loss protocol, and many papers have been written proving this benefit. Metformin is also a CR mimetic, in that it shares many of the health and longevity benefits enjoyed by Caloric Restriction.
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