Guess what happens to cut foreskins?

MarcusG

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Steroid Biochem. 1987 Jan;26(1):131-5.


The influence of 4-hydroxy-4-androstene-3,17-dione on androgen metabolism and action in cultured human foreskin fibroblasts.

Hsiang YH, Berkovitz GD, Brown TR, Migeon CJ, Brodie AM.

4-hydroxy-4-androstene-3,17-dione (4-OHA) has been shown to be a potent inhibitor of aromatase activity. It is effective in the control of estrogen-dependent processes in female subjects and may potentially be useful in the treatment of estrogen-dependent processes in men. Human foreskin fibroblasts grown in cell culture
 

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