Evolutionary Muse Presents: BMP

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  1. Evolutionary Muse Presents: BMP


    Presenting the second in line of the Muscle Building line: BMP: Body Modify - Phenotype. This has been a LONG process to perfect this, but we are ready to go.

    I'll edit this down the road, but for my customers that want to get a jump on it, go ahead and start reading up on Bone Morphogenetic Proteins 2 and 7, and the downstream complex of SMAD 1/5/8 and the master switches involved with the Transforming Growth Factor-beta superfamily, with emphasis on bone morphogenesis, protein synthesis (especially with muscle) and overall phenotype expression.

    These are master switches we are manipulating, in order to trigger favorable expression of lean, muscular phenotype with a HIGHLY strengthened skeletal support system, increase in brown/beige adipose, and suppression of osteoclastogenesis/bone resorption.

    Full writeup will be done in 3-4 week (this is HIGHLY complex) and full product is due in September. This is unlike anything seen by the supplement world before. You will, ideally, stack this wil MyoSynergy and something like X-factor.
    Evolutionary Muse - Inspire to Evolve
    Flawless Skin Couture - We give you the tools to make you Flawless


  2. Is this like a new LeptiGen?
    M.Ed. Ex Phys

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  3. Quote Originally Posted by Rodja View Post
    Is this like a new LeptiGen?
    This goes way beyond the Leptin pathways.
    Evolutionary Muse - Inspire to Evolve
    Flawless Skin Couture - We give you the tools to make you Flawless

  4. Sounds very interesting, I am going to have to do my research. Where do you get these concepts, as in manipulating genes or protein factors to create a higher likelihood of an expressed phenotype?

  5. Read Read Read.

    I spend a minimum of 4 hours a day just reading, and following unfamiliar pathways backwards to see what they control. In the end you wind up with a viable hypothesis of some master control pathways that influence everything downstream.
    Evolutionary Muse - Inspire to Evolve
    Flawless Skin Couture - We give you the tools to make you Flawless
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  6. BMP7 is promising in the obesity area as it increases the production of brown fat cells. What category of product will this be in as it sounded like this will be a lean muscle builder? Or is this a category that is being created much like epi.

  7. Subbed, cause all of your stuff looks so damn good.

  8. Quote Originally Posted by Jackedjack View Post
    BMP7 is promising in the obesity area as it increases the production of brown fat cells. What category of product will this be in as it sounded like this will be a lean muscle builder? Or is this a category that is being created much like epi.
    While the BMP's influence the TGF-b superfamily, it's much different than a simple Myostatin influencer.

    I came up with a hypothesis after a TON of reading about 3 years ago that Bone was the ultimate endocrine "organ", influencing phenotype expression. After a whole lot of research, it appears to be panning out. A balance between osteoblast/osteoclast activity influences overall body type expression indicating anabolic/catabolic states, and it absolutely is open to manipulation.

    You will see much more research in this area popping up, and luckily some of the BMP subtypes are easily manipulated, which means we can tailor the effects we want without undesirable effects.


    *I said influences, when BMP is actually part of the TGF-b superfamily
    Evolutionary Muse - Inspire to Evolve
    Flawless Skin Couture - We give you the tools to make you Flawless

  9. Quote Originally Posted by dsade View Post
    While the BMP's influence the TGF-b superfamily, it's much different than a simple Myostatin influencer. I came up with a hypothesis after a TON of reading about 3 years ago that Bone was the ultimate endocrine "organ", influencing phenotype expression. After a whole lot of research, it appears to be panning out. A balance between osteoblast/osteoclast activity influences overall body type expression indicating anabolic/catabolic states, and it absolutely is open to manipulation. You will see much more research in this area popping up, and luckily some of the BMP subtypes are easily manipulated, which means we can tailor the effects we want without undesirable effects.
    http://www.ncbi.nlm.nih.gov/m/pubmed...777711/related
    It seems that the manipulation of these BMP's will open many different areas in the medical area. This article shows the increases bone fusion rates when BMP 2 is manipulated. Very interesting area of research you are building.

  10. I'm not going to lie...there have been so many days I've wound up with migraines trying to grasp the complete effects of the different BMPs. BMP4 is too complex to target, good or bad, and the others are just way to risky.

    Downstream, if you want to research, look at the SMAD 1/5/8 complex...this really is a master control of both bone anabolism and muscle differentuation/muscle mass.

    We now have several equipotent pathways to manupulate - Myostatin, Androgenic amplification, and now BMP 2 and 7. The end result is going to be a far leaner phenotype with increased muscle mass and performance.

    We are entering a new realm here.
    Evolutionary Muse - Inspire to Evolve
    Flawless Skin Couture - We give you the tools to make you Flawless

  11. Quote Originally Posted by dsade View Post
    I'm not going to lie...there have been so many days I've wound up with migraines trying to grasp the complete effects of the different BMPs. BMP4 is too complex to target, good or bad, and the others are just way to risky. Downstream, if you want to research, look at the SMAD 1/5/8 complex...this really is a master control of both bone anabolism and muscle differentuation/muscle mass. We now have several equipotent pathways to manupulate - Myostatin, Androgenic amplification, and now BMP 2 and 7. The end result is going to be a far leaner phenotype with increased muscle mass and performance. We are entering a new realm here.
    I can't wait to enter this realm, this must have required countless hours of intense research. Good for you, as you will define what innovation truly is.

  12. Quote Originally Posted by Jackedjack View Post
    I can't wait to enter this realm, this must have required countless hours of intense research. Good for you, as you will define what innovation truly is.
    I'm not going to lie...I love it!

    If you think about it, it makes total sense. The skeletal system is the framework of the entire body. If the system starts to malfunction (bone resorption, demineralization, etc) it's a signal to the rest of the body that a severe environmental catastrophe is taking place. Without that strong skeletal anchor, overstrong muscles can tear the body to pieces - so the tie-in just makes so much sense.

    A strong, and strengthening, skeletal system allows for an ever increasing musclular system - working together to forge an ever increasing badass organism.

    BMP - Badass Mother Phucker.
    Evolutionary Muse - Inspire to Evolve
    Flawless Skin Couture - We give you the tools to make you Flawless
  13. AnabolicMinds Site Rep
    Driven2lift's Avatar

    In for the updates & discussion on this, looks like another promising product Dsade
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  14. In for the updates
    SNS REP
    Hit me up with any questions any time.

  15. I don't see this helping my fatter and weaker goals.
    EvoMuse Products Rep

    PM me with any questions!

  16. Hell yes!

  17. Phvcking stoked for this!
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  18. Quote Originally Posted by SwolenONE View Post
    Phvcking stoked for this!
    Hey hey hey...this is a family oriented company
    Evolutionary Muse - Inspire to Evolve
    Flawless Skin Couture - We give you the tools to make you Flawless

  19. By the way, this will also be an excellent stacker with X-factor.
    Evolutionary Muse - Inspire to Evolve
    Flawless Skin Couture - We give you the tools to make you Flawless

  20. Quote Originally Posted by dsade View Post
    By the way, this will also be an excellent stacker with X-factor.
    Reason?

  21. Quote Originally Posted by Jackedjack View Post
    Reason?
    When you hit multiple pathways to increase Muscle Protein Synthesis that do not overlap, and do not work against each other, the effects are additive. X-factor increases MPS through a non-competitive, non-overlapping pathway, which means you will attain fast results.
    Evolutionary Muse - Inspire to Evolve
    Flawless Skin Couture - We give you the tools to make you Flawless

  22. Quote Originally Posted by dsade View Post
    When you hit multiple pathways to increase Muscle Protein Synthesis that do not overlap, and do not work against each other, the effects are additive. X-factor increases MPS through a non-competitive, non-overlapping pathway, which means you will attain fast results.
    Thats cool, when this comes out nutra better have a stack for sale

  23. Quote Originally Posted by Jackedjack View Post
    Thats cool, when this comes out nutra better have a stack for sale
    Don't worry, I've already spoken to Molecular and we're going to make it happen.
    Evolutionary Muse - Inspire to Evolve
    Flawless Skin Couture - We give you the tools to make you Flawless

  24. Quote Originally Posted by dsade View Post
    Don't worry, I've already spoken to Molecular and we're going to make it happen.
    This shall be epic. My wallet will need time to recover after this.

  25. Quote Originally Posted by Jackedjack View Post
    This shall be epic. My wallet will need time to recover after this.
    You're gonna appreciate the thinner wallet anyway....those thicker quads and glutes need room.
    Evolutionary Muse - Inspire to Evolve
    Flawless Skin Couture - We give you the tools to make you Flawless

  26. Quote Originally Posted by dsade View Post
    You're gonna appreciate the thinner wallet anyway....those thicker quads and glutes need room.
    Well then why don't we just have an evomuse sale so that wallet of mine is empty for my new founded thunder thighs

  27. Subbed. In many years of following your products, I do not think I have ever been let down.

  28. so glad i decided to stash my xgels away for a while, saving them for this :P and that xfactor deal with them sounds great.

  29. Quote Originally Posted by dsade View Post
    This goes way beyond the Leptin pathways.
    Oh lord, i could never grasp those write ups...I'm gonna bust out the lokaine to focus on the one you are working on.

    Excited to see what this is...i now have something to google if work gets slow tomorrow.

    Edit: meant leptigen write ups, not leptin...i need to pay more attention
    "I am on a drug, it's called Charlie Sheen. It's not available, 'cause if you try it once, you will die. Your face will melt off and your children will weep over your exploded body." - Charlie Sheen

  30. I applaud your integrity and dedication to relentless innovation. This one and Seethe are the ones I really got my fingers crossed for now!
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