New E-pharm product: URSOBOLIC !

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  1. Quote Originally Posted by truthornothin View Post
    I don't think he intentionally loaded it. He was using raw powder at the start not capped, in another post I read that his early dosing was haphazard and he settled into the suggested dose.
    Thanks man! Figured it was something like that!

    Hey man, never knew you were a E-pharm rep. congratz!
    RecoverBro ELITE


  2. Quote Originally Posted by mattrag View Post
    Thanks man! Figured it was something like that!

    Hey man, never knew you were a E-pharm rep. congratz!
    As of this afternoon, thanks
    E-PHARM Nutrition Representative
    Better one ugly truth than a million pretty lies
    Check Out Ur-Spray and D-Serine at Prototype Nutrition



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  3. Quote Originally Posted by truthornothin View Post
    As of this afternoon, thanks
    Hehe nice, hope the Ursobolic run goes well. I ordered from Amazon but I got no shipping confirmation... been like a week. Thinking of cancelling and ordering through SP.... then I can get it shipped to me in Japan... Amazon wouldn't let me...had it shipped to my Hawaii address...
    RecoverBro ELITE

  4. Quote Originally Posted by ax1 View Post
    No not facetious at all. Sometimes people post studies they run into here in these related threads to continue the dialogue.

    Im using Ursobolic as we speak, so my intent isnt to discredit the product either.
    Most of the studies I have found are positive especially regarding cancer prevention this one on prostate cancer got my attention, my dad had prostate cancer. This caught my interest
    Ursolic Acid Suppresses Interleukin-17 (IL-17) Production by Selectively Antagonizing the Function of RORγt Protein*
    Tao Xu‡,1, Xiaohu Wang§,1,2, Bo Zhong§, Roza I. Nurieva§,3, Sheng Ding‡,4 and Chen Dong§,5
    + Author Affiliations

    From the ‡Gladstone Institute of Cardiovascular Disease, Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158 and
    the §Department of Immunology and Center for Inflammation and Cancer, M.D. Anderson Cancer Center, Houston, Texas 77030
    ↵4 Supported by funding from the National Institutes of Health through NICHD, NHLBI, and the National Institute of Mental Health, the California Institute for Regenerative Medicine, the Prostate Cancer Foundation, Fate Therapeutics, the Esther B. O'Keeffe Foundation, and the Scripps Research Institute. To whom correspondence may be addressed. E-mail: [email protected].
    ↵5 Supported by grants from the National Institutes of Health through NIAMS, the Leukemia and Lymphoma, Society, and the M.D. Anderson Cancer Center. To whom correspondence may be addressed. E-mail: [email protected].
    ↵1 Both authors contributed equally to this work.

    Abstract

    Th17 cells have recently emerged as a major player in inflammatory and autoimmune diseases via the production of pro-inflammatory cytokines IL-17, IL-17F, and IL-22. The differentiation of Th17 cells and the associated cytokine production is directly controlled by RORγt. Here we show that ursolic acid (UA), a small molecule present in herbal medicine, selectively and effectively inhibits the function of RORγt, resulting in greatly decreased IL-17 expression in both developing and differentiated Th17 cells. In addition, treatment with UA ameliorated experimental autoimmune encephalomyelitis. The results thus suggest UA as a valuable drug candidate or leading compound for developing treatments of Th17-mediated inflammatory diseases and cancer.

    Cytokine Immunology Inflammation Nuclear Receptors Transcription Regulation RORg Th17
    Footnotes

    ↵2 Recipient of a National Multiple Sclerosis Society (NMSS) postdoctoral fellowship.
    ↵3 Supported by NIH through NIAID.
    ↵* A patent disclosure has been filed by M.D. Anderson Cancer Center based on the results of this paper.
    ↵ The on-line version of this article (available at http://www.jbc.org) contains supplemental Figs. S1 and S2.
    Received April 12, 2011.
    Revision received May 4, 2011.
    © 2011 by The American Society for Biochemistry and Molecular Biology, Inc.
    CiteULike Connotea Delicious Digg Facebook Google+ LinkedIn Mendeley Twitter
    What's this?
    E-PHARM Nutrition Representative
    Better one ugly truth than a million pretty lies
    Check Out Ur-Spray and D-Serine at Prototype Nutrition




  5. Quote Originally Posted by mattrag View Post
    Hehe nice, hope the Ursobolic run goes well. I ordered from Amazon but I got no shipping confirmation... been like a week. Thinking of cancelling and ordering through SP.... then I can get it shipped to me in Japan... Amazon wouldn't let me...had it shipped to my Hawaii address...
    I bought mine from amazon, 2 bottles for $45 had it in three days. Oh well the price you pay for being in first. I am eating more carbs and just more recklessly in general thus far to know ill effect, been starving myself to stay cut through the summer months. Eating is good,eating what I want even better, within reason
    E-PHARM Nutrition Representative
    Better one ugly truth than a million pretty lies
    Check Out Ur-Spray and D-Serine at Prototype Nutrition



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  6. Quote Originally Posted by MAxximal View Post
    is from Sage Extract (75% ursolic acid)

    ANALYTE SPEC. RESULT
    Ursolic Acid 75% 80.2%
    Oleanolic Acid ... 9.67%

    ASSAY: URSOLIC ACID AND OLEANOLIC ACID BY HPLC Total ... 89.9%


    and is ULTRA EXPENSIVE
    9 to 18 caps ED...if it has the benefits it says I can pretty much toss off a lot of other stuff, run it with C-Bolic and my staples to stay lean.

    Might also run the other later to see if it has merit. 6-oxo and 11-oxo worked well for me so I figure PA is onto something with this one as well. Still wish he'd sell it in a powder as well. I could just pop out a scoop and go.

  7. Yeah a powder would be much better for dosing too, and maybe the price would be more economical?.

  8. Would this be worth running on an actual PH cycle or would it be overkill?

  9. Quote Originally Posted by houstontexas View Post
    Would this be worth running on an actual PH cycle or would it be overkill?
    Unless its a cycle u are familiar with I would save your money.
    RecoverBro ELITE

  10. Quote Originally Posted by houstontexas View Post
    Would this be worth running on an actual PH cycle or would it be overkill?
    This compound has many protective properties and can definitely be stacked with anything. If you don't want to run it on cycle it would be an excellent addition to pct
    E-PHARM Nutrition Representative
    Better one ugly truth than a million pretty lies
    Check Out Ur-Spray and D-Serine at Prototype Nutrition




  11. Quote Originally Posted by truthornothin
    This compound has many protective properties and can definitely be stacked with anything. If you don't want to run it on cycle it would be an excellent addition to pct
    Only thing I worry about is the dosing protocol for liver protection. Aside from that the appetite suppression you reported on your log could be detrimental in pct if one were to use this on a mass gain cycle.

    IMO a recomp on hdrol or epi on a second or third run would be a good gauge. Mainly so you know how you react on the oral and because patrick arnold said it's more for leaning out.
    With more research this could be the ultimate addition to the whole cycle (pct included) but no one has exp on it yet.
    I'm thinking of running a epi recomp on ursobolic later this year.
    RecoverBro ELITE

  12. As a lifelong natty i am all for supps that are all natural and actually work, if i was to take only 2 products one being a natty test booster (as test is borderline) would testforce 2 stacked with ursobolic be a good stack (of which i have tried neither)

    Aimed at PA and truth-
    i wish to loose approx 4-5lbs to be reasonably ripped at close approximation it would make me 7-9%bfat
    from your experience could ursobolic make fat loss possible with me continuing to eat at maintenence cals (approx 2500-2600cals, without decreasing cals or the addition of cardio
    ?

    If UA is as good as it appears it could be for fat loss specifically without much effort, i would prob buy and use more than anyone lol

  13. Quote Originally Posted by miniarnold View Post
    As a lifelong natty i am all for supps that are all natural and actually work, if i was to take only 2 products one being a natty test booster (as test is borderline) would testforce 2 stacked with ursobolic be a good stack (of which i have tried neither)

    Aimed at PA and truth-
    i wish to loose approx 4-5lbs to be reasonably ripped at close approximation it would make me 7-9%bfat
    from your experience could ursobolic make fat loss possible with me continuing to eat at maintenence cals (approx 2500-2600cals, without decreasing cals or the addition of cardio
    ?

    If UA is as good as it appears it could be for fat loss specifically without much effort, i would prob buy and use more than anyone lol
    I am on day 11 of Ursobolic, check out my log post of today with progress pics. I do not do cardio, its boring and I hate it. I am putting Ursobolic to the test I am eating above maintenance and have really freed myself up on the carbs. I am consuming a lot more of them with no apparent ill effect. I am currently using TF2 and Ursobolic as my primary stack. It is working quite well. I am actually 2 lbs lighter than when I started Ursobolic that and eating above maintenance. I think that is a realistic expectation as I've lost two pounds in 10 days eating above maintenance, but everyone's metabolism is different. Truthornothin's Ursobolic Log The Whole Truth and Nothing But the Truth!
    E-PHARM Nutrition Representative
    Better one ugly truth than a million pretty lies
    Check Out Ur-Spray and D-Serine at Prototype Nutrition




  14. Quote Originally Posted by houstontexas View Post
    Lockout!
    Lockout?
    E-PHARM Nutrition Representative
    Better one ugly truth than a million pretty lies
    Check Out Ur-Spray and D-Serine at Prototype Nutrition




  15. Quote Originally Posted by houstontexas View Post
    Lockout!
    not sure what that blurtout is aimed at....BUT if it's what i think....then it's the same reason im here reading thru this thread. the D.O.T.D. is hard to turn down.
    -It's not about what you're doing, it's about how you're doing it.

  16. Quote Originally Posted by 808rebel View Post
    not sure what that blurtout is aimed at....BUT if it's what i think....then it's the same reason im here reading thru this thread. the D.O.T.D. is hard to turn down.
    Thanks for the reps, not I gotcha. That just kinda came out of nowhere lol
    E-PHARM Nutrition Representative
    Better one ugly truth than a million pretty lies
    Check Out Ur-Spray and D-Serine at Prototype Nutrition




  17. Quote Originally Posted by truthornothin View Post
    Thanks for the reps, not I gotcha. That just kinda came out of nowhere lol
    reps FTW...but yeah i know, i thought it was hilarious that lockout brought me here, and the first thing i read was someone blurting it out. I saw someone get banned for mentioning them, better watch out bro!
    -It's not about what you're doing, it's about how you're doing it.

  18. Quote Originally Posted by truthornothin View Post
    Place to purchase items?
    I googled it. It is a store. They have stuff on sale. Personally I'm gonna wait for Nutraplanet, no matter how long it takes them to get stuff in stock. I don't have the money right now anyway.

  19. Quote Originally Posted by 808rebel View Post
    reps FTW...but yeah i know, i thought it was hilarious that lockout brought me here, and the first thing i read was someone blurting it out. I saw someone get banned for mentioning them, better watch out bro!
    Ha ha. I edited my post....

  20. lookout maybe?

  21. Quote Originally Posted by truthornothin View Post
    Lockout?
    L*ck*ut Suppl*m*nts and have the best price on Ursobolic

  22. Quote Originally Posted by Orangatang

    L*ck*ut Suppl*m*nts and have the best price on Ursobolic
    Lockout is the best, always by my supps from them.

  23. Edited for fear of dictator rule...

  24. How'd I miss this thread. D'OH!

    Interesting to say the least
    A-Minds HYPE-SLAYER! All posts & feedback are guaranteed to be unsolicited and legit
    "The fear of the LORD is the beginning of knowledge. Fools despise wisdom & instruction"
    Proverbs 1:7
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