E-Pharm Test Force 2: Formula Write Up and ETA

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  1. E-Pharm Test Force 2: Formula Write Up and ETA


    Introducing E-Pharm Test Force 2



    TestForce2 contains the most soluble form of d-aspartic acid combined with another remarkable amino acid known as sarcosine. This combination provides results clearly superior to other d-aspartic acid product formulations.




    In case you arenít aware, d-aspartic acid is the hottest supplement ingredient on the market right now. It has more scientific literature supporting its ability to act as a natural regulator of anabolic hormone (i.e. testosterone, growth hormone) release in the body than any supplement ingredient EVER. And E-Pharm was the company to bring you the premium form of d-aspartic acid Ė d-aspartate calcium chelate. This form is more than 75 times as water soluble as regular d-aspartic acid and soluble over a wide pH range. This ensures the most rapid and complete absorption possible.


    And now E-Pharm has taken the lead in d-aspartic acid technology again with the patent pending addition of the amino acid sarcosine.

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    Please allow me to explain why the inclusion of sarcosine is so vital to getting the most out of d-aspartic acid.

    Why Sarcosine?

    Let me start with some background. When d-aspartic acid (DAA) is ingested it is absorbed into the body and taken up preferentially by endocrine tissues such as the hypothalamus, pituitary, and testicles. There it stimulates the activity of what are known as NMDA receptors. NMDA receptors are located on neurons and they regulate neuronal activity. DAA binds to a specific docking site (receptor) located on the NMDA receptor known as NMDA binding site.



    In the hypothalamus the stimulation of NMDA receptors leads to the production of gonadotropin releasing hormone (GnRH). GnRH then stimulates the pituitary gland to release luteinizing hormone (LH) and follicle stimulating hormone (FSH). LH and FSH then in turn travel to the testicles to initiate the process of steroidogenesis, which leads eventually to the release of testosterone into the blood stream. Stimulation of NMDA receptors in the hypothalamus also leads to the release of growth hormone releasing hormone (GHRH) which in turn promotes the release of growth hormone from the pituitary gland.


    So the key here is the NMDA receptor. The more you activate this receptor in the hypothalamus the greater the release of GnRH and GHRH, and ultimately testosterone and growth hormone.



    The NMDA receptor is somewhat unique in that it requires activaton by two ligands (a ligand is like a ďkeyĒ to a receptor). In the hypothalamus the main ligand for the NMDA receptor is d-aspartic acid. The secondary ligand (or co-activator) is the amino acid glycine. Both DAA and glycine have specific binding sites on the NMDA receptor. These sites are known as the NMDA binding site and the glycine binding site respectively. Think of it this way - just like how firing a nuclear missile requires two soldiers to turn two separate keys, so the NMDA receptor requires binding by two ligands to initiate its influence on the firing of a neuronal signal.


    So to review, administration of DAA leads to itís uptake into the hypothalamus and binding to the NMDA receptors there. And to activate the NMDA receptor you also require adequate levels of ligands that bind to the glycine site of the NMDA receptor. Now common sense would lead one to assume that by ingesting supplemental amounts of glycine would ensure that glycine site co-activation is ensured. However the scientific literature has shown that this method has limited efficacy.


    The reason that glycine administration is not very effective at stimulating NMDA activity is not completely straight forward, but one reason is because it is efficiently removed from the synapses by the reuptake regulator Glycine Transporter 1 (GT1).



    Interestingly, much of the science published on the subject of stimulaton of NMDA receptor activity revolves around the theory that NMDA receptor hypo-activity is a causative factor in schizophrenia. For years scientists have been investigating ways to stimulate NMDA activity as a means for treating schizophrenic patients. One of the most effective strategies has been through targeting the GT1 protein. And one of the most efficient means to do this is actually through supplementation with sarcosine.


    Of course we arenít concerned about treating schizophrenia here, what we are concerned with is maximally stimulating natural production of testosterone (or growth hormone) But the mechanism in question is exactly the same for both purposes. By blocking the re-uptake of glycine you increase the concentration of glycine in neuronal synapses, and therefore increase the influence of NMDA upon nerve transmission. In essence this is the exact way some anti-depressants (such as SSRIs) work, except the goal there is to increase binding and activating of serotonin or dopamine receptors, not NMDA receptors.



    Blocking glycine reuptake is not the only mechanism through which sarcosine stimulates DAA activity. Sarcosine actually can itself bind to the glycine binding site of NMDA receptors. In fact, it binds with a higher affinity than even glycine. So basically it replaces glycine as well as serves as its own reuptake inhibitor. It totally solves the glycine co-activation issue in one shot.


    Knowing all these facts you can see why sarcosine produces a rather dramatic effect on NMDA neuronal transmission compared to glycine itself, or other endogenous ligands for the glycine receptor such as d-serine.

    Conclusion

    To summarize, for d-aspartic acid to work to its maximum potential it must be taken with an efficient stimulator of the glycine binding site on the NMDA receptor. The most efficient non-drug stimulator we know of is the natural amino acid sarcosine.
    TestForce2 contains 3 grams of d-aspartic acid (as d-aspartate calcium chelate) and 3 grams of sarcosine per serving. It also is flavored with a light fruit punch flavor and slightly sweetened to provide a very pleasurable taste experience. It dissolves almost instantly.


    So if you like d-aspartic acid you will love TestForce2. And if you were one of the few ďnon-respondersĒ to d-aspartic acid then you will also love TestForce2 because you will no longer be a non-responder. You would be a fool to settle for any other d-aspartic acid supplement.



    ETA: 3 weeks


  2. cant wait to pick this up!
    •   
       


  3. me too!
    Quote Originally Posted by bdcc View Post
    If you are not on the PES Insider list you are not cool. Uncool people don't deserve free Alphamine.
    PES product educator, PM me with any questions!

  4. ...can't wait...

    CEL Rep

  5. IN for the Presale!!!
    Evolutionary Muse - Inspire to Evolve
    Flawless Skin Couture - We give you the tools to make you Flawless

  6. Sweet!!!!
    SNS Online Representative
    Maxximal @ seriousnutritionsolutions.com

    Got Glycophase ...?



  7. The good got even better!!
    Always open light. Itís not what you open with, itís what you finish with. Louie Simmons

  8. very curious how sarcosine was found as the final piece to the puzzle.this is a very interesting combo.

  9. bring on pre sale!

  10. I think Pat really did his home work here, I was looking into other things a few months ago to increase NMDA activity while taking DAA. I think the key to DAA is the NMDA activity, I cant wait to try this.

  11. product sounds interesting, time for me to do some reading
    Athletic Xtreme Marketing Manager
    Athletic Xtreme at The Planet!
    Email Inquiries: Brandon@AthleticX.net

  12. Price??

  13. Definitely interested in seeing how this pans out

  14. First time I have heard of this product, but sounds worth trying after I do a bit more research.

  15. Quote Originally Posted by 2buff View Post
    First time I have heard of this product, but sounds worth trying after I do a bit more research.
    Pretty much better soluble DAA lol..
    It is proven to work.
    Backed by studies and blood work.

  16. Quote Originally Posted by gamer2be08 View Post
    Price??
    i read same price as testforce is now... we could see a 29.99 price though.

  17. Quote Originally Posted by Primal2 View Post
    i read same price as testforce is now... we could see a 29.99 price though.

    we have not changed the price from the original
    Anabolicminds.com Featured Author

  18. wow price is good..

  19. Great article in this month's MD! I WILL be using this product as my bridge between PCT and next cycle(s) into the future.

  20. Bravo.
    Gause institute member

    Need2slin designer.Product designer/ **** admin.

  21. Really looking forward to this. Will it contain as much (90 grams) DAA as V1 per tub?

  22. If sarcosine has been used to ameliorate schizophrenia, it seems it could have psychological affects on normal people. Off hand, and knowing little, it seems it could make a person feel slow-minded (the opposite of schizophrenia). Any thoughts?

  23. Quote Originally Posted by Cogrick2 View Post
    If sarcosine has been used to ameliorate schizophrenia, it seems it could have psychological affects on normal people. Off hand, and knowing little, it seems it could make a person feel slow-minded (the opposite of schizophrenia). Any thoughts?
    Neither the science nor the user reports support your supposition.
    Antśus Labs rep

  24. Quote Originally Posted by Cogrick2 View Post
    If sarcosine has been used to ameliorate schizophrenia, it seems it could have psychological affects on normal people. Off hand, and knowing little, it seems it could make a person feel slow-minded (the opposite of schizophrenia). Any thoughts?
    http://www.ncbi.nlm.nih.gov/pubmed/20397623
    http://www.ncbi.nlm.nih.gov/pubmed/18842900
    http://www.ncbi.nlm.nih.gov/pubmed/17981050
    http://www.jneurosci.org/cgi/content/short/28/41/10404
    http://www.ncbi.nlm.nih.gov/pubmed/20097447
    Antśus Labs rep

  25. So we know a release date yet? halfway through the month already...

  26. Quote Originally Posted by MasterMind View Post
    Really looking forward to this. Will it contain as much (90 grams) DAA as V1 per tub?
    each jar will contain 90 grams of DAA (as Ca Chelate) and 90 grams sarcosine

    Quote Originally Posted by Cogrick2 View Post
    If sarcosine has been used to ameliorate schizophrenia, it seems it could have psychological affects on normal people. Off hand, and knowing little, it seems it could make a person feel slow-minded (the opposite of schizophrenia). Any thoughts?
    uhhhh...whuh???


    Quote Originally Posted by Primal2 View Post
    So we know a release date yet? halfway through the month already...
    September 22nd is our target date for shipping
    Anabolicminds.com Featured Author

  27. Quote Originally Posted by Cogrick2 View Post
    If sarcosine has been used to ameliorate schizophrenia, it seems it could have psychological affects on normal people. Off hand, and knowing little, it seems it could make a person feel slow-minded (the opposite of schizophrenia). Any thoughts?
    Sarcosine is said to alleviate both positive and negative symptoms of schizophrenia. The definition of positive and negative symptoms as presented in wikipedia is the following



    Positive and negative symptoms

    Schizophrenia is often described in terms of positive and negative (or deficit) symptoms.[17] The term positive symptoms refers to symptoms that most individuals do not normally experience but are present in schizophrenia. They include delusions, auditory hallucinations, and thought disorder, and are typically regarded as manifestations of psychosis. Negative symptoms are things that are not present in schizophrenic persons but are normally found in healthy persons, that is, symptoms that reflect the loss or absence of normal traits or abilities. Common negative symptoms include flat or blunted affect and emotion, poverty of speech (alogia), inability to experience pleasure (anhedonia), lack of desire to form relationships (asociality), and lack of motivation (avolition). Research suggests that negative symptoms contribute more to poor quality of life, functional disability, and the burden on others than do positive symptoms.[
    Anabolicminds.com Featured Author

  28. Quote Originally Posted by henryv View Post
    Order is in. I can't wait

  29. The only issue I have is with the number of containers you would need to follow the dosing protocol recommended.
    Always open light. Itís not what you open with, itís what you finish with. Louie Simmons

  30. Quote Originally Posted by AZMIDLYF View Post
    The only issue I have is with the number of containers you would need to follow the dosing protocol recommended.
    Ever try one scoop a day? It will last a month. Thats all I use now.

  31. PA, how many containers would you recommend for a decent cycle of this stuff? Big difference in results of a 4 week run compared to say a 6-8 week run?

  32. I've read of no advantage of taking more than one scoop a day.

  33. It looks like they want you to load for the first 3 weeks then go maintenance. I haven't run DAA solo but I just started taking it in another supplement with additional compounds.
    Always open light. Itís not what you open with, itís what you finish with. Louie Simmons

  34. Quote Originally Posted by Primal2 View Post
    Ever try one scoop a day? It will last a month. Thats all I use now.
    Quote Originally Posted by AZMIDLYF View Post
    The only issue I have is with the number of containers you would need to follow the dosing protocol recommended.
    Don't forget TF2 has twice as much in, due to the added Sarcosine. So where with TF1 you'd take 1 scoop, with TF2 you take two scoops per serving, and there's 26 servings in the tub, not 26 scoops.
    Antśus Labs rep

  35. Supplement Facts
    Serving Size: 1 scoop (3.45g)
    Servings per Container: 26

    Amount Per Serving % Daily Value
    D-Aspartic acid
    (as D-Aspartate Calcium Chelate) 3000 mg **
    Sarcosine 3000 mg **
    Calcium
    (as D-Aspartate Calcium Chelate) 451 mg 45%

    * Percent Daily Values are based on a 2000 calorie diet.
    ** Percent Daily Values not established.

    Other Ingredients: Citric Acid, Malic Acid, Natural & Artificial Flavors, Aspartame, Acesulfame K


    Directions:
    Consume 2 scoops twice a day for three weeks. Afterwards consume 1 scoop a day. Cycles can last from three weeks to three months Preferably consume with food

    Dosing directions above^^^. It also says serving size is 1 scoop and there are 26 servings per tub for TF2.
    Always open light. Itís not what you open with, itís what you finish with. Louie Simmons

  36. Quote Originally Posted by henryv View Post
    Don't forget TF2 has twice as much in, due to the added Sarcosine. So where with TF1 you'd take 1 scoop, with TF2 you take two scoops per serving, and there's 26 servings in the tub, not 26 scoops.
    Alright, maybe its the lack of current blood sugar, but now I'm confused. SO with TF2, one scoop does not contain 3g of DAA? I would need two scoops? too get that equivalent?

  37. Quote Originally Posted by AZMIDLYF View Post
    Supplement Facts
    Serving Size: 1 scoop (3.45g)
    Servings per Container: 26

    Amount Per Serving % Daily Value
    D-Aspartic acid
    (as D-Aspartate Calcium Chelate) 3000 mg **
    Sarcosine 3000 mg **
    Calcium
    (as D-Aspartate Calcium Chelate) 451 mg 45%

    * Percent Daily Values are based on a 2000 calorie diet.
    ** Percent Daily Values not established.

    Other Ingredients: Citric Acid, Malic Acid, Natural & Artificial Flavors, Aspartame, Acesulfame K


    Directions:
    Consume 2 scoops twice a day for three weeks. Afterwards consume 1 scoop a day. Cycles can last from three weeks to three months Preferably consume with food

    Dosing directions above^^^. It also says serving size is 1 scoop and there are 26 servings per tub for TF2.
    I expect NP used the info from the TF1 profile. It's inaccurate.

    Quote Originally Posted by lonewolf0420 View Post
    Alright, maybe its the lack of current blood sugar, but now I'm confused. SO with TF2, one scoop does not contain 3g of DAA? I would need two scoops? too get that equivalent?
    Yeah. One 3g scoop will be half sarcosine and half DAA, so you'll need two scoops for one serving.
    Antśus Labs rep

  38. Yeah, you should really have NP update that info. IF I knew the corrected info, I wouldn't have placed my order. I respond just fine to the original.
  

  
 

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