[Ninjo]

Is Designer Supplements still making Rebound XT? I can't seem to find it anywhere; all the online retail stores seem to be sold out. I understand that Rebound Reloaded was intended as an alternative for those who experienced significant loss of libido on ATD but can RR really match ATD when it comes to estrogen control (i.e. via aromatase inhibition) and testosterone increase?

[wrkn4bigrmusles]

think its Rebound Reloaded now... but dont quote me

[bigpetefox]

Reloaded is a totally new AI, and according to my latest bloodwork I'd say alot better than ATD..

[Sldgehmr]

According to the main studies and research done on a handful of AI's it was far better then most, especially because it seems to have a much longer halflife then ATD. Let me try to find the study and ill post it, its a great read and really changes the way I thought about ki values and their potency.

[wastedwhiteboy2]

do you have an estimate of the halflives?
good you see you post again.

[Sldge]

It was a huge difference, like ATD was in minutes, whereas 6-bromo was in hours. Ill pull the study and get the real figures but it was an eye opener. It completely changed how I view AI's.
I was always under the assumption that the KI value was everything, it isnt. Its really a combo of being potent enough to inhibit the enzyme but it also needs to be in the blood long enough to actually work. That seems to be the problems with most. They arent around long enough to have a full effect. We fixed that in Reloaded.

[xcendo]

I'm just curious - how long does it take for 6-bromo to start effectively inhibiting aromatase action? Does it work at the first dose?

[Sldge]

IIRC at 36 hours it had a 50% inhibition and continued to climb from there with continued dosing.If I can access my old computer (bad virus problem) Ill check my notes for it.