• Published Study DMAA Is Safe

      By Shane Starling Nutra Ingredients USA

      A study of 25 healthy men has found DMAA-containing, pre-workout sports supplement, Jack3D, does not change resting heart rate, blood pressure or affect liver and kidney function when used at recommended dosage levels.

      The 10-week study, published in the Journal of Nutrition and Metabolic Insights, compared Jack3D users with those consuming a placebo. Both control and intervention groups were told to consume the supplements 30 minutes before exercise work outs on selected days.

      “Our data indicate that a dietary supplement containing 1,3-dimethylamylamine (DMAA) does not significantly increase resting heart rate or blood pressure (although systolic blood pressure increased ∼6 mmHg with the supplement),” wrote the researchers from the University of Memphis.

      “Moreover, the supplement does not adversely impact bloodborne biomarkers of health,but rather, results in a decrease in LDL-C [cholesterol].”

      The randomised, double blind study was sponsored by USP Labs, the manufacturer of Jack3D, which in addition to DMAA, contains caffeine, creatine monohydrate, alanine, schinzandrol A, and arginine alpha-ketoglutarate.

      The authors noted that the rise in systolic blood pressure meant, “those with elevated blood pressure to avoid use of dietary supplements containing 1,3-dimethylamylamine.”

      They also called for further study with bigger study groups.

      Of the cholesterol reduction, they noted: “The supplement results in a small decrease in LDL-C, which may suggest a potential cardioprotective role. While this may have clinical relevance, additional studies inclusive of larger samples are needed to replicate these findings, as well as to extend and expand upon other findings associated with this work.”

      USP Labs’ joined the researchers in observing that the studies were, “consistent with previous 2-week and 8-week studies which found no significant increase in blood pressure or liver and kidney function following chronic use of DMAA & DMAA-containing supplements.”

      Jack3D and other pre-workout supplements have been deemed an unauthorised drug in the UK and Canada due to the presence of DMAA, but they are sold widely in other countries and the internet.

      DMAA has been linked to deaths in the US military, is the subject of at least two class actions in the US and is under investigation by authorities in several European countries.

      Source: Journal of Nutrition and Metabolic Insights

      February 2012. doi: 10.4137/NMI.S8885

      ‘Impact of a Dietary Supplement Containing 1,3-Dimethylamylamine on Blood Pressure and Bloodborne Markers of Health: a 10-Week Intervention Study’

      Authors : Paul N. Whitehead, Brian K. Schilling, Tyler M. Farney and Richard J. Bloomer

      Source: http://mobile.nutraingredients-usa.c...%2BText%2BNews
      Comments 4 Comments
      1. jonesBones40's Avatar
        jonesBones40 -
        Sponsored by USP Labs huh?
      1. Mmyamahar6's Avatar
        Mmyamahar6 -
        I dont want to see 1,3 dmaa leave I love it thumbs up to corporations protecting their own products
      1. USPlabsRep's Avatar
        USPlabsRep -
        Originally Posted by jonesBones40 View Post
        Sponsored by USP Labs huh?

        Yes sir, 5 University Studies...This is just one of them
      1. jonesBones40's Avatar
        jonesBones40 -
        Originally Posted by USProduct-Edu View Post
        Yes sir, 5 University Studies...This is just one of them
        Have never trusted studies about a product sponsored by the same company, how do you think MuscleTech gets such ridiculous claims that they beat to death to sell their products. Not saying USP is anything like Muscletech, USPs products are much better. But I will not trust an independant study more.
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