• Obese Dads Have Obese Kids

      From Science Daily

      If you are obese and hope to be a father, here's another reason to lose weight: your children and grandchildren may inherit your waistline or metabolic disorders. That's because scientists have discovered in mice that obese fathers, even those who did not show any signs of diabetes, passed this negative trait on most frequently to their daughters. Sons don't entirely dodge this genetic bullet either -- both sons and daughters of obese fathers have increased risks of developing metabolic diseases, such as diabetes.

      "If these findings hold true in humans, then a father's diet and body composition at the time of conception is likely to affect his future child's health and risk of lifelong disease," said Tod Fullston, Ph.D., a researcher involved in the work from the Department of Obstetrics & Gynaecology at the Robinson Institute, Research Centre for Reproductive Health at the University of Adelaide in South Australia. "Fathers should aim to be as healthy as possible at the time of conception to give future generations the best possible chance of good health."

      To make this discovery, Fullston and colleagues used two groups of male mice. One was fed a high-fat diet that resembled a "fast food" diet and the other was fed a nutritious control diet. When compared to the control group, the group fed the "fast food" diet gained weight and had an increase in fat (obesity) without any indications of diabetes. The two groups of male mice were then mated to normal weight control diet-fed females to produce first generation mice, which were also mated to normal weight control diet-fed mice to produce the second generation. Both generations of mouse offspring had metabolic disorders and obesity, with the only difference being their father's/grandfather's diet, although male/female offspring had different health problems. By comparing small RNA molecules (microRNAs) in sperm from the obese mice as compared to the control mice, researchers deduced that changes in these molecules might be partly responsible for the transmission of these conditions from father to offspring. This suggests that diet changes the molecular makeup of sperm, which in turn, program embryos and their risk of metabolic and reproductive health problems. The research also suggests that these adverse health outcomes may be transmitted into the second generation as well.

      "We've known for quite some time that obesity is a serious problem for children of expectant mothers," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal, "and now we see that obesity is likely a serious problem for children of obese fathers as well. Hopefully as more research emerges to support these findings, future fathers will find ways to slim down, if not for themselves, then for their children and grandchildren."

      Story Source:
      The above story is reprinted from materials provided by Federation of American Societies for Experimental Biology, via EurekAlert!, a service of AAAS.
      Note: Materials may be edited for content and length. For further information, please contact the source cited above.

      Journal Reference:
      Tod Fullston, E. Maria C. Ohlsson Teague, Nicole O. Palmer, Miles J. Deblasio, Megan Mitchell, Mark Corbett, Cristin G. Print, Julie A. Owens, And Michelle Lane. Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA. FASEB Journal, 2013 DOI: 10.1096/fj.12-224048

      Source: http://www.sciencedaily.com/releases...Weight+Loss%29
      Comments 4 Comments
      1. fueledpassion's Avatar
        fueledpassion -
        Hey!! There is a thought of the day, lol.

        It's not all hereditary though. It's probably just as much influence to the child by simply being around a fat dad or fat parents who dont eat right and don't necessarily encourage or force activity on the child. Even if they did force healthy activity and diet, when the child hits teen years, they'll just view their parents as hypocritical and wont likely take heed to their request in being healthy. In my opinion, parental influence is the largest factor in anything about a person/child.

        "Like father, like son"

        "The apple doesn't fall far from the tree"
      1. mikeg313's Avatar
        mikeg313 -
        Them some tetays!
      1. etnukekav's Avatar
        etnukekav -
        nice tits
      1. Bobert's Avatar
        Bobert -
        Originally Posted by mikeg313 View Post
        Them some tetays!
        For real!
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